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Scientists have created the most detailed maps yet of how genes control one another inside the brains of people with Alzheimer’s disease. Using a powerful new AI-based system called SIGNET, the team uncovered cause-and-effect relationships between genes across six major brain cell types, revealing which genes are truly driving harmful changes. The most dramatic disruptions were found in excitatory neurons, where thousands of genetic interactions appear to be extensively rewired as the disease progresses.
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ScienceDaily
An East Bay apartment complex has been bought at a price that's well below its prior value. Read more ›
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A PG&E Corp. unit has bought a San Jose building in a move to bolster the utility's South Bay operations. Read more ›
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YouTube TV is reportedly still ironing out ESPN Unlimited issues ahead of WrestleMania 42. Read more ›
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Meta is preparing a new round of layoffs, setting May 20 as the starting point for cuts that will affect roughly 8,000 employees, or about 10% of its global workforce, according to an exclusive report from Reuters. The move marks ... Read more ›
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An anonymous reader quotes a report from Wired: Sam Altman's iris-scanning, humanity-verifying World project announced at an event in San Francisco on Friday that Tinder users around the globe can now put a digital badge on their profiles signaling to potential suitors that they're a real human, provided they've already stared into one of World's glossy white Orbs and allowed their eyes to be scanned. The announcement follows a pilot... Read more ›
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NJ Transit hikes train fares to $150 per round-trip for the FIFA World Cup at MetLife Stadium, and only 40,000 tickets per game will be available. Read more ›
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Powerful six-bay AI enhanced NAS featuring specifications that you’d usually see in a PC. Read more ›
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Southwest may have long had a reputation for being budget-friendly and simplified, but it looks like they're eager to drop that with these new changes. Read more ›
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Last month, OpenAI gave up on its Sora video generation tool, and on Friday, the Sora team's leader, Bill Peebles, announced that he is leaving the company. OpenAI has been shifting its priorities as part of an effort to avoid "side quests," and Peebles' departure is just one of many recent changes as the company […] Read more ›
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Celebrities like Matthew McConaughey, Sylvester Stallone, and Chris Hemsworth left Los Angeles for other places that offer privacy and lower taxes. Read more ›
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Group founded by former engineers at DeepMind and OpenAI secures $4bn valuation in deal with Google’s venture arm and Nvidia Read more ›
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В прошлой статье я разобрал почему Claude Code ломает проекты (context drift, отсутствие CLAUDE.md, нет хуков на тесты) и как выстроить защиту от регрессий. Статья попала в топ-5 Хабра за сутки — видимо, проблема задела нерв.Но в комментариях и в личных сообщениях всплыл вопрос, который я тогда обошёл стороной: а что с самими токенами? Контекстное окно стало миллион, но агент всё равно жрёт его как не в себя. Куда уходят... Read more ›
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В предыдущей статье "Облако своими руками для расчета пространственных стержней методом конечных элементов на Node js, React js и Three js" представлен краткий обзор облачного SPA приложения ammonit3d по моделированию пространственных стержневых систем (ферм, балок, рамных и связевых конструкций, опор ЛЭП) методом конечных элементов с численно-аналитическим решением для каждого конечного элемента, в основе которого математическая модель Эйлера-Бернулли - механическая модель упругой балки или стержня длиной. Read more ›
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The crew of NASA's Artemis II mission have safely returned to Earth, but if your Moon fever has yet to break, or you're curious to get a big picture view of how the second of a planned five Moon missions was pulled off, PBS has a new documentary you'll want to watch. The hour-long Return to the Moon was produced for PBS' NOVA and aired on TV on April 15,... Read more ›
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Paramount's failure to clog up the leaks of the new 'Last Airbender' movie is just the latest in a long line of unfortunate events for the franchise. Read more ›
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If you do your own yard work, an Ego rechargeable combo kit available at Lowe's might be a good option if you want well-reviewed yard tools. Read more ›
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The Galaxy Z TriFold proved Samsung could build the future. It also proved that the future sells out embarrassingly fast when you only make 30,000 of them. Read more ›
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ScienceDaily
Researchers have uncovered why a rare blood clotting disorder can occur after certain COVID-19 vaccines or adenovirus infections. The immune system can mistakenly target a normal blood protein (PF4) after confusing it with a viral protein. This triggers clotting in extremely rare cases. The breakthrough means vaccines can now be redesigned to avoid this reaction while staying effective. Read more ›
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Losing your sense of smell might signal Alzheimer’s far earlier than expected. Scientists found that immune cells in the brain actively destroy smell-related nerve fibers after detecting abnormal signals on their surfaces. This damage begins in early stages of the disease, well before cognitive decline. The discovery could help identify at-risk patients sooner and improve treatment timing. Read more ›
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Scientists have achieved the unthinkable by stabilizing a highly reactive molecule in water, confirming a decades-old theory about vitamin B1’s role in the body. The breakthrough not only solves a scientific mystery but could revolutionize greener chemical manufacturing. Read more ›
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Scientists searching for air pollution clues stumbled onto something unexpected: toxic MCCPs drifting through the air for the first time in the Western Hemisphere. The likely source—fertilizer made from sewage sludge—points to a hidden route for contamination. Read more ›
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A major study suggests that when you eat could play a key role in staying lean. People who fast longer overnight and start their day with an early breakfast were more likely to have a lower BMI years later. Scientists think this is because eating earlier aligns better with the body’s internal clock. But skipping breakfast as part of intermittent fasting didn’t offer the same advantage—and may even be tied... Read more ›
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Putting on weight earlier in life may be more dangerous than previously thought. Researchers found that early adulthood obesity significantly raises the risk of premature death, especially from major diseases like heart disease and diabetes. The longer the body carries excess weight, the greater the damage appears to be. Interestingly, cancer risk in women didn’t follow this pattern, suggesting other biological factors are at play. Read more ›
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A major international effort has produced an ultra-precise measurement of the Universe’s expansion rate, confirming it’s faster than early-Universe models predict. By linking multiple distance-measuring techniques, scientists ruled out simple errors as the cause of the discrepancy. The persistent “Hubble tension” now looks more real than ever. It could mean our current model of the cosmos is incomplete. Read more ›
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Mars may be hostile, but it might not be entirely unlivable. In lab experiments, yeast cells survived simulated Martian shock waves and toxic perchlorate salts—two major environmental threats on the Red Planet. Their secret weapon was forming protective molecular clusters that shield critical cellular functions under stress. Without these defenses, survival plummeted, pointing to a potential universal strategy life could use beyond Earth. Read more ›
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A new nanodisc-based platform lets scientists study viral proteins in a form that closely mimics real viruses, revealing how antibodies truly recognize them. This approach uncovered hidden interactions in viruses like HIV and Ebola that traditional methods missed. By recreating the virus’s membrane environment, researchers can better understand how immune defenses work. The technique could speed up the development of more effective vaccines. Read more ›
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Researchers are launching a new project to crack the mystery of aggressive breast cancer, where predicting disease progression remains a major hurdle. By studying how tumors interact with and suppress the immune system, scientists aim to identify new biomarkers that reveal how the cancer evolves. Using real patient samples, the team hopes to turn earlier discoveries into practical clinical tools. The goal: more precise, personalized treatments that can outsmart even... Read more ›
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17.04.2026 17:46
Last update: 17:40 EDT.
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