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379 Zebrafish protein unlocks dormant genes for heart repair

ScienceDaily
ScienceDaily 3 place · 01/02/2025 16:26 EDT

Zebrafish protein unlocks dormant genes for heart repair

Researchers have successfully repaired damaged mouse hearts using a protein from zebrafish. They discovered that the protein Hmga1 plays a key role in heart regeneration in zebrafish. In mice, this protein was able to restore the heart by activating dormant repair genes without causing side effects, such as heart enlargement. This study marks an important step toward regenerative therapies to prevent heart failure.

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