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Researchers have discovered that GPR31, found in certain immune cells in the human gut, plays a key role in responding to bacterial metabolites and activating immune responses. Specifically, in the presence of metabolite pyruvate, these cells extend dendrites to sample the gut environment, detect pathogens, and activate T cells through GPR31. This discovery could inform the development of new drugs, vaccines, and probiotics that enhance gut immunity by targeting this pathway.
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ScienceDaily
Hitman developer IO Interactive has cut ties with MMA fighter Conor McGregor, following last week's Irish High Court ruling that found he had assaulted and raped a woman in December 2018. Read more Read more ›
2,203 fresh
Photo by Mario Tama/Getty Images California Governor Gavin Newsom vowed to bring back the state’s rebate for new electric vehicle purchases if President-elect Donald Trump follow through on his threat to kill the federal tax credit. During the campaign, Trump vowed to eliminate President Joe Biden’s “EV mandate” on “day one” of his presidency. And now with this transition underway, his advisors have already discussed including a measure to kill... Read more ›
1,951 fresh
An ongoing furnace issue at Tesla's Texas factory raised the temperature and created a "constant haze," The Wall Street Journal reported. Read more ›
1,927 fresh
Notable Silicon Valley figures like Joe Lonsdale and Marc Andreessen are involved in DOGE's planning, The Wall Street Journal reported. Read more ›
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Researchers at the International Energy Research Centre (IERC), based at Tyndall National Institute, are leading research into the use of artificial intelligence (AI) to develop a deeper understanding of the complex factors impacting energy poverty. The project, entitled the Irish Energy Poverty Observatory (IREPO), aims to provide a unique platform that will enable research, development, […] Read more ›
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Susan Wojcicki, a non-smoker and CEO of YouTube, was diagnosed with non-small cell lung cancer in 2022 at the age of 56. She died in 2024. Read more ›
848 fresh
Save over $100 on the Sony's noise-cancelling over-the-ears headphones for Black Friday. Read more ›
804 fresh
Apple today revealed its 2024 App Store Awards finalists, including pro video camera app Kino, which is in the running for iPhone App of the Year. There are 45 finalists across 12 categories, including a first-ever Apple Vision Pro category. Apple said the awards recognize developers who delivered the "highest levels of user experience, design, and innovation" on the App Store this year. Kino was released earlier this year by... Read more ›
751 fresh
The Verge Roku is making it easier to find and watch its programming on Google TV without jumping between apps. Users can soon search for content from The Roku Channel — Roku’s free streaming app — directly on Google TV, providing quick access to Roku’s library of over 80,000 movies and TV shows. New category tabs are coming to the Google TV home screen that will suggest recommended Roku content,... Read more ›
738 fresh
Since launch, Tesla's polarizing electric pickup has been beset by quality issues, and is now heading to be one of the most unreliable EVs made yet. Strangely, Cybertruck owners may not care one bit. Read more ›
692 fresh
An array of Ubisoft games including Star Wars Outlaws, Assassin's Creed Valhalla and Avatar: Frontiers of Pandora are broken on some devices running Windows 11 with version update 24H2 installed. Read more Read more ›
684 fresh
Sony is developing a portable version of the PlayStation 5, according to a new report. Read more Read more ›
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Judges and legal scholars worry that AI-generated evidence, or false claims about AI-generated evidence, will derail and prolong cases. Read more ›
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Apple CEO Tim Cook on Monday made his third visit to China this year, ahead of a five-day supply chain conference with Chinese Premier Li Qiang and other corporate leaders (via Bloomberg). The Apple chief joined more than 20 global business leaders in meetings with Premier Li Qiang, including executives from Rio Tinto, Corning, and Charoen Pokphand Group. Chinese corporate leaders from Lenovo Group and ICBC were also present at... Read more ›
625 fresh
President-elect Donald Trump and Elon Musk have become an inseparable duo. Since Trump’s reelection, the richest man in the world — and one of Trump’s top campaign donors — has been a shadow trailing him at his Florida residence. The tech billionaire has taken center stage in the incoming administration, promising to slash $2 trillion […] Read more ›
600 fresh
Netflix and Riot Games' utterly brilliant Arcane will be followed by three further series exploring other parts of the League of Legends world. Read more Read more ›
577 fresh
Kurt Campbell, the US deputy secretary of state, said China is being kept in the dark about the friendship between Kim Jong Un and Vladimir Putin Read more ›
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Vice President Sara Duterte said she had talked to a hitman to kill her boss if she herself were to be killed, saying she was making "no joke." Read more ›
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ScienceDaily
In an era of dwindling glaciers, Southern Patagonia has managed to hold on to a surprising amount of its ice. But, a new study suggests that this protective effect might be pushed up against its limits soon. Read more ›
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As we age, our muscles atrophy. Earlier this year, researchers found that hepatocyte growth factor (HGF), a protein critical in skeletal muscle development loses its functionality due to nitration as we age. Now, the same team has developed a monoclonal antibody that blocks the nitration sites of HGF, effectively preventing the protein's age induced loss of function. Their findings were validated utilizing rat muscles cell culture. Read more ›
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Dairy cows typically rest for 10 or more hours a day, so a dry, clean, and comfortable place -- such as a freestall -- to lie down and rest is essential for their health, well-being, and production performance. One key factor in whether stalls are comfortable for cows is the ease with which they can get up and down, so it is common on farms for staff to watch for... Read more ›
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Resembling a seahorse, as its name implies from the Greek words 'hippos' (horse) and 'kampus' (sea monster), the hippocampus is a brain region crucial for memory formation. But until recently, scientists have not been able to link memory formation to distinct molecular signals. Now, a team of scientists likely opened this black box. Read more ›
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Weight-loss and diabetes drug tirzepatide can reduce the risk of death or worsening heart failure for patients with obesity and heart failure with preserved pump function, new research reveals. Read more ›
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Archaeologists have collected data which indicates the presence of a large-scale pre-Columbian fish-trapping facility. Discovered in the Crooked Tree Wildlife Sanctuary (CTWS), the largest inland wetland in Belize, the team dated the construction of these fisheries to the Late Archaic period (cal. 2000-1900 BCE), pre-dating Amazonian examples by a thousand years or more. Read more ›
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The Wistar Institute and the University of Buea in Cameroon has uncovered the mechanisms for a medicinal plant with anti-HIV potential in Croton oligandrus Pierre & Hutch, a species of African tree that has been used in traditional healing in Cameroon to treat a variety of diseases and conditions including cancers and diabetes. Read more ›
51
Defining cerebral palsy only as a childhood condition fails to acknowledge the many adults living with the disease. Read more ›
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Hepatitis E viruses (HEV) typically cause liver infections. They can, however, also infect other organs and cause neurological disorders. Little is yet known about how this process works. A research team has now developed a cell model to study the interaction of the virus with nerve cells. Using this model, the researchers proved that the virus can infect the cells directly and that the cells can't protect themselves against it... Read more ›
43
Researchers used the Dark Energy Spectroscopic Instrument to map how nearly 6 million galaxies cluster across 11 billion years of cosmic history. Their observations line up with what Einstein's theory of general relativity predicts. Read more ›
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Most popular sources
Business Insider
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34% 0 |
Eurogamer.net
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9% 4 |
Gizmodo
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7% 1 |
Android Authority
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6% 4 |
CNET
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6% 2 |
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25.11.2024 10:42
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