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A new type of degenerative brain disease, limbic-predominant age-related TDP-43 encephalopathy (LATE), was recognized just a decade or so ago, and remains relatively unknown. In the disease, the TDP-43 protein accumulates particularly in the limbic brain regions, which are also affected in the early stages of Alzheimer's disease. Accordingly, symptoms of LATE are similar to those of early Alzheimer's, but typically progress more slowly and are milder.
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ScienceDaily
Netflix's new limited series dives into the personal life of Ayrton Senna, who had a wife and many girlfriends. Read more ›
675 fresh
Putin called Trump "a smart and experienced person," who can find "a solution" to the Ukraine war. Trump previously vowed to end the war in 24 hours. Read more ›
606 fresh
After building real-estate wealth from high housing prices, boomers are facing a shortage of suitable retirement housing. Read more ›
573 fresh
Chinese firms are on edge and so are some of their US partners. Markets are relatively muted, though the yuan is down. Read more ›
562 fresh
The US blocked Turkey from buying F-35 fighters because of security concerns over its Russian S-400 air defenses. Trump may help Turkey undo the ban. Read more ›
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In this article, we discuss how the key to brand success lies in not ‘chasing trends,’ but embracing an agile, data-driven approach that prioritises real-time insights and responsiveness. Connecting with consumers in a meaningful way Today’s brands, in and outside of Southeast Asia, face a constant challenge: Cutting through the noise and connecting with consumers... Read more » Read more ›
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We rounded up more than 20 great Lego deals live ahead of Black Friday, including the Lego Orchid for $39.99 or the Lego Infinity Gauntlet for $45. Read more ›
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Here's another look at the not so sparkly Galaxy S25 and S25 Plus color options. Read more ›
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Buy 2 Months, Get 1 Month FREE on Mint Mobile's best-selling 3-month 5GB plan Read more ›
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Joe Biden said Donald Trump's plan to impose a 25% tariff on Mexican and Canadian imports is "counterproductive." Read more ›
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"You know how people go for smoke breaks? I need a squishy break," the "APT" singer said. Read more ›
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Brussels-based AnyKrowd, a company specialised in the event and crowd management with an all-in-one solution, announced on Friday that it has secured €4M in a Series A funding round. Out of the total, finance&invest.brussels invested €1M. Other investors, including Michael Verschueren, Tony Mary, David Mary, Gio Canini, and Frank Van Raemdonck, also participated. “This funding ... Read more Read more ›
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"I was not really fully emotionally baked until shortly before I met Mary," Ted Danson, who married Mary Steenburgen in 1995, said. Read more ›
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Intel must maintain majority control of its foundries as a condition of receiving $7.86 billion in U.S. CHIPS Act funding, according to terms disclosed in a regulatory filing [PDF]. The semiconductor giant will need to keep at least 50.1% ownership if the foundry unit is spun off privately, while no single shareholder can hold more than 35% of shares if it goes public unless Intel remains the largest stakeholder. The... Read more ›
127 fresh
A second batch of cream top whole raw milk from Raw Farm in California just tested positive for bird flu. Read more ›
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We’ve probably got enough foodies on the Engadget staff to start our own restaurant. While we’re not all home chefs (some of us just microwave), we all love food. So we’ve used, tested and reviewed plenty of kitchen gadgets for the site. Right now for Black Friday, a lot of the gear we’ve tried is currently on sale. We found deals on air fryers, sous vide machines, pizza ovens and... Read more ›
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Whether you stay at home or brave the Black Friday crowds, you can find some of the lowest prices of the year. Read more ›
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Here are some hints — and the answers — for Connections No. 537 for Black Friday, Nov. 29. Read more ›
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ScienceDaily
In an era of dwindling glaciers, Southern Patagonia has managed to hold on to a surprising amount of its ice. But, a new study suggests that this protective effect might be pushed up against its limits soon. Read more ›
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Researchers recently collaborated on a novel, highly specific strategy to treat type 1 diabetes (T1D) using a tagged beta cell transplant in tandem with localized immune protection provided by specialized immune cells also tagged with a complementary but inert targeting molecule. Read more ›
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Physical reservoir computing (PRC) utilizing synaptic devices shows significant promise for edge AI. Researchers from the Tokyo University of Science have introduced a novel self-powered dye-sensitized solar cell-based device that mimics human synaptic behavior for efficient edge AI processing, inspired by the eye's afterimage phenomenon. The device has light intensity-controllable time constants, helping it achieve high performance during time-series data processing and motion recognition tasks. This work. Read more ›
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Archaeologists have collected data which indicates the presence of a large-scale pre-Columbian fish-trapping facility. Discovered in the Crooked Tree Wildlife Sanctuary (CTWS), the largest inland wetland in Belize, the team dated the construction of these fisheries to the Late Archaic period (cal. 2000-1900 BCE), pre-dating Amazonian examples by a thousand years or more. Read more ›
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A new study warns that current plans to achieve zero emissions on the grid by 2050 vastly underestimate the required investments in generation and transmission infrastructure. The reason: these plans do not account for climate change's impacts on water resources. Specifically, changes in water availability caused by climate change could decrease hydropower generation by up to 23% by the year 2050, while electricity demand could increase by 2%. Read more ›
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Infants whose mothers regularly use language to describe what their child is thinking or feeling, have higher levels of the hormone oxytocin, finds a new study. Read more ›
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An international team of researchers has made new observations of an unusual supernova, finding the most metal-poor stellar explosion ever observed. Read more ›
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Researchers found a reduction in cervical cancer mortality in women under the age of 25, which is likely due to the introduction of the HPV vaccine. Read more ›
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Scientists have recently identified electrons and positrons with the highest energies ever recorded on Earth. They provide evidence of cosmic processes emitting colossal amounts of energy, the origins of which are as yet unknown. Read more ›
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You may have heard sleep described as something of a magic pill for the body. With the right amount, timing, and quality, it can work wonders -- strengthen the immune system, improve blood sugar, even decrease the risk of heart attacks and strokes. Sleep differences have been reported for some time in men and women, but it is not well known whether the characteristics of sleep serve different functions in... Read more ›
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29.11.2024 05:37
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