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505 New small molecule could treat sickle cell disease in adults that don't respond to hydroxyurea, alone

ScienceDaily
ScienceDaily · 07/31/2024 17:09 EDT

New small molecule could treat sickle cell disease in adults that don't respond to hydroxyurea, alone

Researchers found a small molecule that increases fetal hemoglobin production in human blood stem cells and leads to fewer sickled red blood cells in mice, providing proof of principle for developing more effective therapeutics for sickle cell disease.

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