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932 Knockout of CD5 on CAR T cells boosts anti-tumor efficacy

ScienceDaily
ScienceDaily · 07/22/2024 15:50 EDT

Knockout of CD5 on CAR T cells boosts anti-tumor efficacy

The effectiveness of CAR T cell therapy against a variety of cancers, including solid tumors, could be boosted greatly by using CRISPR-Cas9 technology to knock out the gene for CD5, a protein found on the surface of T cells, according to a preclinical study.

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