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925 Shedding light on the origin of a genetic variant underlying fungal infections

ScienceDaily
ScienceDaily · 06/11/2024 13:04 EDT

Shedding light on the origin of a genetic variant underlying fungal infections

Variants in the CARD9 gene increase susceptibility to severe fungal infections. However, individuals in different parts of the world tend to carry specific CARD9 variants, making it complex to track the origin of these mutations. In a recent study, a research team conducted genetic analyses on Japanese, Korean, and Chinese patients, revealing that they all shared a variant of CARD9 stemming from a common ancestor from less than 4,000 years ago.

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