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Scientists have uncovered a hidden reason why cancer treatments don’t work equally well for everyone. Certain drugs can become trapped inside lysosomes within tumor cells, forming slow-release reservoirs that create uneven drug distribution. This means some cancer cells are heavily exposed while others are barely affected. Understanding this process could help doctors better tailor treatments and improve outcomes.
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ScienceDaily
An East Bay apartment complex has been bought at a price that's well below its prior value. Read more ›
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A PG&E Corp. unit has bought a San Jose building in a move to bolster the utility's South Bay operations. Read more ›
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I was unsure if my parents would notice that the voice on the other end wasn't mine - or that it was mine, sort of, but it wasn't me. The voice said hello, asked my dad how he was doing, and asked again when he didn't respond quickly enough. "What is that, Gaby?" He realized […] Read more ›
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Casely first recalled over 429,000 of its 5,000mAh Power Pods wireless power banks in April 2025 following 51 reports of their lithium-ion batteries "overheating, expanding or catching fire," resulting in six minor burn injuries. Both the company and the US Consumer Product Safety Commission (USCPSC) are reannouncing the same recall today following 28 additional reports […] Read more ›
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Standing in my childhood kitchen, I watched my father check my tire pressure for the third time this visit while the words "I love you" sat unspoken between us like a family heirloom nobody knows how to use. Read more ›
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Данный таск был частью 5 сезона CTF, который проходил на площадке ACLabs. Машина необычная с увлекательным сюжетом и интересными уязвимостями.Условие задачи:Борис — старый почтовый голубь. Катя, его голубка, улетела к наглому Воробью. Три дня Борис пил дешёвое пойло и строчил план мести. Теперь этот план у тебя. Помоги Борису пробраться в цифровое гнездо Воробья, украсть его аккаунт и стать рутом. Следуй за пьяными записками — там всё сказано и даже... Read more ›
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AMD's Ryzen 9 9950X3D2 has started appearing at retailers, with Amazon currently offering the CPU at $1,000 — $100 above the suggest retail pricing. Read more ›
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Last year, Apple achieved its goal of removing all plastic from the packaging of its products – now every Apple gadget you buy comes in 100% fiber-based packaging that you can recycle at home. The gadgets themselves feature a lot of recycled materials. The company used 30% recycled materials across the products that it shipped last year. And in three specific areas, the recycled content is 100%: all Apple-designed batteries... Read more ›
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After six weeks of fighting, Israel and Lebanon appear to be on the verge of a ceasefire. President Donald Trump announced the 10-day pause, which he said would help “achieve PEACE” between the countries, in a social media post on Thursday. The ceasefire is set to take effect at 5 pm ET. The agreement came […] Read more ›
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Chinese fantasy novels reimagine the past with modern tech and ideology. A new book argues they also help reinforce authoritarian politics. Read more ›
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He taught me to fix everything in a house except the crushing weight of inherited silence, and now I'm learning the language of feelings at forty like a child learning to speak. Read more ›
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Sherbrooke firm secures first private capital after deploying its tech in space. Read more ›
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Playdate is getting a third season of curated, surprise games, Panic announced today. We don't know much beyond the fact that Season Three is officially happening, but Panic's Head of Playdate Greg Maletic said in an announcement video that it will be here "in time for the holidays" this year. Considering we had to wait a whole three years for Season Two to come out following Season One's release with... Read more ›
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'Dungeon Masters' will feature both current and unreleased material from the legendary TTRPG in its first in-house actual play series. Read more ›
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Anna’s Archive avoided the $13 trillion sought in the lawsuit, but the final bill is still eye-watering. Read more ›
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ScienceDaily
A breakthrough in microbiome research could change how colorectal cancer is detected—no colonoscopy required. Scientists used AI to map gut bacteria at an unprecedented level of detail, revealing subtle microbial patterns linked to cancer. By analyzing simple stool samples, their method identified 90% of cases, rivaling one of medicine’s most trusted diagnostic tools. Read more ›
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Cancer drugs known as BET inhibitors once looked like a breakthrough, but in real patients they’ve often fallen short. New research reveals a key reason why: two closely related proteins, BRD2 and BRD4, don’t actually do the same job. Instead, BRD2 acts like a “stage manager,” preparing genes for activation, while BRD4 triggers the final step that turns them on. By blocking both at once, current drugs may be disrupting... Read more ›
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A mysterious glow of gamma rays at the center of the Milky Way has long hinted at dark matter, but the lack of similar signals in smaller dwarf galaxies has cast doubt on that idea. Now, researchers propose a bold twist: dark matter might not be a single particle at all, but a mix of two different types that must interact with each other to produce detectable signals. Read more ›
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A new chip design from UC San Diego could make data centers far more energy-efficient by rethinking how power is converted for GPUs. By combining vibrating piezoelectric components with a clever circuit layout, the system overcomes limitations of traditional designs. The prototype achieved impressive efficiency and delivered much more power than previous attempts. Though not ready for widespread use yet, it points to a promising future for high-performance computing. Read more ›
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Perovskite solar cells shouldn’t work as well as they do—but they do. Scientists have now discovered that defects inside the material actually help, creating networks that separate and guide electric charges efficiently. Using a novel imaging method, they revealed hidden structures acting like charge “highways.” This insight could unlock even more powerful, low-cost solar cells. Read more ›
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A strange new kind of superconductivity has been uncovered in uranium ditelluride (UTe2), where electricity flows with zero resistance—but only under extremely strong magnetic fields that should normally destroy it. Even more surprising, the superconductivity disappears at first and then dramatically reappears at even higher fields, earning it the nickname the “Lazarus phase.” Read more ›
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Scientists have proposed a surprising new way to detect gravitational waves—by observing how they change the light emitted by atoms. These waves can subtly shift photon frequencies in different directions, leaving behind a detectable signature. The effect doesn’t change how much light atoms emit, which is why it’s gone unnoticed until now. If confirmed, this approach could lead to ultra-compact detectors using cold-atom systems. Read more ›
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A common eye-health nutrient, zeaxanthin, may also help the body fight cancer more effectively. Scientists discovered it strengthens T cells and enhances the impact of immunotherapy treatments. Found in everyday vegetables and supplements, it’s safe, accessible, and shows strong potential as a cancer therapy booster. Human trials are the next step. Read more ›
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Alzheimer’s isn’t just one problem—it’s a tangled mix of biology, aging, and overall health. That’s why drugs targeting a single factor have fallen short, even as new treatments show modest benefits. Scientists are now pushing toward multi-pronged strategies, from gene editing to brain-cell rejuvenation and gut health interventions. The goal: stop treating Alzheimer’s as one disease and start tackling it as a complex system. Read more ›
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Researchers have uncovered why a rare blood clotting disorder can occur after certain COVID-19 vaccines or adenovirus infections. The immune system can mistakenly target a normal blood protein (PF4) after confusing it with a viral protein. This triggers clotting in extremely rare cases. The breakthrough means vaccines can now be redesigned to avoid this reaction while staying effective. Read more ›
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16.04.2026 14:59
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