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Researchers discovered that leucine, a nutrient found in protein-rich foods, can supercharge mitochondria by protecting crucial energy-producing proteins inside cells. The breakthrough uncovers a powerful new link between diet and cellular energy — with possible implications for cancer and metabolic disease treatments.
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ScienceDaily
An East Bay apartment complex has been bought at a price that's well below its prior value. Read more ›
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A PG&E Corp. unit has bought a San Jose building in a move to bolster the utility's South Bay operations. Read more ›
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San Francisco startup Fearn wants to help companies and inventors do more patent work before they ever call a lawyer. Read more ›
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Researchers found a trojanized X-VPN installer used to deploy STX RAT malware. X-VPN itself was not breached, and only attacker-hosted downloads are affected. Read more ›
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The deal is available for offline purchases only, but there are some good online alternatives too. Read more ›
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Guest post by Edward Rowe is the author of The Standard Model for Business and a governance, assurance, and risk executive with more than twenty-one years of experience advising boards, investment leaders, and executive teams globally. Growth is one of the most misunderstood stages in business. Most organisations focus heavily on revenue growth, customer acquisition, and market expansion. Yet many […] Read more ›
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MIT's 3D-printed triaxial electrospray nozzles could revolutionize drug and self-healing material manufacturing. By using a relatively inexpensive resin printing approach, the new nozzle fabrication technique removes the need for a semiconductor-class cleanroom facility. Read more ›
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Kalshi is rolling out a new set of compliance measures designed to curb insider trading and market manipulation across its… Continue reading Kalshi adds compliance safeguards amid ongoing insider trading concerns Read more ›
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Andy Kofoid, president of global field operations at Databricks, advises against blindly following the common advice to follow your passion. Read more ›
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Many were surprised to learn that Gears of War: E-Day would be an Xbox console exclusive on its release and skip PlayStation 5, but the series' original creator believes this is a wise move by the platform holder. Read more Read more ›
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![[Перевод] Опасности первичных ключей UUID в SQLite и оптимизация данных](https://times42.com/media/8/3/5/12558835_640x200.jpg "[Перевод] Опасности первичных ключей UUID в SQLite и оптимизация данных")
В базах данных в качестве первичных ключей часто используют случайные UUID. Один из известных недостатков случайных UUID заключается в том, что их неупорядоченность (UUID4) может вызывать большое количество дополнительных обращений к страницам кластеризованных индексов (clustered index), потому что строки вставляются в случайные места B-дерева, и его приходится постоянно перебалансировать. В этой статье я попытаюсь помочь вам выработать более интуитивное понимание того, как влияют на производительность все. Read more ›
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Если вы пишете код, или так или иначе задействованы в разработке ПО, или просто следите за тем, как ИИ меняет разработку, то наверняка слышали тревожный тезис: «Скоро ИИ будет писать код лучше людей, и разработчики станут не нужны». На интуитивном уровне кажется, что если машина делает ту же работу в 8 раз быстрее, то бизнесу нужно в 8 раз меньше людей. Но экономика и история индустрии говорят об обратном —... Read more ›
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Penn State researchers have developed a light-adaptive sensor inspired by the human eye that could help self-driving cars and robots maintain visual accuracy in changing lighting conditions. Read more ›
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Как правило, автоматизация складского учета идет по похожим сценариям. Внедряется адресное хранение, сотрудники получают терминалы сбора данных, в учетной системе появляются ордера и ячейки. Некоторое время этого достаточно: склад работает, остатки контролируются, заказы отгружаются.Но через несколько лет после внедрения компания начинает сталкиваться с проблемами. Ассортимент увеличивается с сотен до тысяч позиций. Появляются разные схемы комплектации. Растет количество сотрудников и техники. Склад начинае Read more ›
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Pricing changes after a boom in AI coding left companies with sticker shock. Now, executives are grappling with a new era. Read more ›
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Get all-round coverage with one camera. Read more ›
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New York health officials accused alloClae's manufacturer, Tiger Aesthetics, of smuggling the product into the state and seized one doctor's supply. Read more ›
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Microsoft's Office 2019 apps for Mac will stop working next month, because the company isn't renewing a certificate that validates Office licenses. Owners of Office 2019 for Mac are being warned they'll have to purchase Office 2024 or a Microsoft 365 subscription if they want to continue editing documents. Microsoft previously promised that "all your […] Read more ›
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ScienceDaily
An ancient mountain cave in the Pyrenees may have served as one of the earliest high-altitude mining camps ever discovered, with evidence of repeated visits spanning thousands of years. The find becomes even more intriguing with the discovery of a child’s remains and clues that deeper excavations could uncover prehistoric burials. Read more ›
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One of the most powerful typhoons ever recorded this early in the Pacific season did more than unleash flooding and extreme winds—it sent enormous ripples all the way into the upper atmosphere. As Super Typhoon Sinlaku rapidly exploded into a category 5-equivalent storm, satellites captured rare gravity waves spreading outward like rings on a pond, visible high above Earth through a faint glow in the atmosphere. Read more ›
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Typhoon Jangmi powered toward southern Japan with heavy rain, strong winds, and a striking appearance from space. Nighttime satellite images revealed a large eye and intricate swirling structures within the storm. As Jangmi intensified, its outer bands spread over land, raising concerns about flooding and prolonged downpours across parts of Japan. Read more ›
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Researchers discovered a way to reverse the direction of energy flow in turbulence, challenging a theory that has stood for more than 80 years. The finding could open new possibilities for controlling ocean currents, improving medical technologies, and enhancing climate forecasting. Read more ›
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A newly identified group of amygdala neurons appears to play a central role in anxiety and social behavior. Restoring normal activity in this tiny brain circuit reversed anxiety and social deficits in mice, revealing a promising new target for future treatments. Read more ›
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Scientists have developed an experimental diabetes and obesity pill that works in a completely different way from drugs like Ozempic. Rather than reducing hunger, it activates metabolism in skeletal muscle, helping lower blood sugar and increase fat burning while preserving muscle mass. Early clinical results suggest the treatment is safe and well tolerated. Read more ›
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A massive study of more than 600,000 U.S. veterans suggests that popular GLP-1 drugs such as semaglutide may do far more than help with diabetes and weight loss—they could also fight addiction itself. Researchers found that people taking these medications were less likely to develop substance use disorders involving alcohol, nicotine, cannabis, cocaine, opioids, and other drugs, while those already struggling with addiction experienced fewer overdoses, hospitalizations, emergency visits, and... Read more ›
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Scientists at Lawrence Livermore National Laboratory recreated part of the intense chaos inside a nuclear fireball to better understand how radioactive fallout forms. Their experiments revealed that the way vaporized materials cool can dramatically change the particles that eventually form, especially for volatile elements like cesium. Read more ›
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June's night sky delivers several must-see events, starting with a close encounter between Venus and Jupiter after sunset. Mercury joins the pair to form a rare three-planet lineup, while the Moon puts on a special show by passing in front of Venus for viewers in parts of the Americas. The month also marks the start of astronomical summer and the return of spectacular deep-sky targets like the Ring Nebula and... Read more ›
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NASA's James Webb Space Telescope has uncovered unusual chemistry in interstellar comet 3I/ATLAS, including the first direct detection of methane on a visitor from another star system. The comet also contains exceptionally high levels of carbon dioxide, making it unlike most comets born in our solar system. Scientists believe the methane was hidden beneath the surface and only emerged after solar heating reached deeper icy layers. Read more ›
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10.06.2026 05:47
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