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A protein tied to ALS and dementia may have a much bigger role in disease than scientists realized. Researchers found that TDP43 controls a key DNA repair process, but when the protein becomes imbalanced, the repair system can spiral out of control, harming neurons and destabilizing DNA. The team also discovered that high levels of the protein are linked to increased mutation rates in cancer. The discovery places TDP43 at the center of both neurodegeneration and cancer biology.
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An East Bay apartment complex has been bought at a price that's well below its prior value. Read more âș
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A PG&E Corp. unit has bought a San Jose building in a move to bolster the utility's South Bay operations. Read more âș
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Đа ŃŃĐŸĐč ĐœĐ”ĐŽĐ”Đ»Đ”, 2 апŃДлŃ, ĐžŃĐżĐŸĐ»ĐœĐžĐ»ĐŸŃŃ 234 ĐłĐŸĐŽĐ° ĐĐŸĐœĐ”ŃĐœĐŸĐŒŃ ĐŽĐČĐŸŃŃ ĐĄĐšĐ. ĐĄĐ”ĐłĐŸĐŽĐœŃ ŃŃĐŸ ĐČŃŃĐŸĐșĐŸŃĐ”Ń ĐœĐŸĐ»ĐŸĐłĐžŃĐœŃĐč ĐșĐŸĐœĐČĐ”ĐčĐ”Ń, ĐČŃЎаŃŃĐžĐč ĐŽĐŸ 28 ĐŒĐ»ŃĐŽ ŃĐœĐžŃĐŸĐČ ĐČ ĐłĐŸĐŽ. ĐĐŸ Đ”ŃлО ĐŒŃ Đ·Đ°ĐłĐ»ŃĐœĐ”ĐŒ ĐżĐŸĐŽ ĐșĐ°ĐżĐŸŃ ŃŃĐŸĐč ĐžĐœĐŽŃŃŃŃОО, ŃĐŸ ĐŸĐ±ĐœĐ°ŃŃĐ¶ĐžĐŒ, ŃŃĐŸ ĐŒĐŸĐœĐ”ŃĐœŃĐč ĐŽĐČĐŸŃ â ŃŃĐŸ ŃŃаŃĐ”ĐčŃĐžĐč ĐČ ĐŒĐžŃĐ” ĐżŃĐžĐŒĐ”Ń ŃŃĐ°ĐœĐŽĐ°ŃŃОзаŃОО, Đ±ĐŸŃŃĐ±Ń Ń Â«ĐČĐ·Đ»ĐŸĐŒĐŸĐŒÂ» (ĐżĐŸĐŽĐŽĐ”Đ»ĐșĐ°ĐŒĐž) Đž ĐżŃĐŸĐŒŃŃĐ»Đ”ĐœĐœĐŸĐč аĐČŃĐŸĐŒĐ°ŃОзаŃОО.РазбОŃĐ°Đ”ĐŒŃŃ, ĐșаĐș ŃĐ”ĐșĐ°ĐœĐșа ĐŒĐŸĐœĐ”Ń ĐżŃĐ”ĐČŃаŃОлаŃŃ ĐžĐ· ĐșŃŃŃаŃĐœĐŸĐłĐŸ ŃĐ”ĐŒĐ”Ńла ĐČ ĐČŃŃĐŸĐșĐŸŃĐŸŃĐœŃĐč ŃĐ”Ń ĐżŃĐŸŃĐ”ŃŃ. ЧОŃаŃŃ ĐŽĐ°Đ»Đ”Đ” Read more âș
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Đ Đ°ĐœĐłĐ»ĐŸŃĐ·ŃŃĐœĐŸĐŒ ĐżŃĐŸŃŃŃĐ°ĐœŃŃĐČĐ” ŃŃŃĐ”ŃŃĐČŃĐ”Ń ŃŃŃаŃДгОŃ: INCUP (Interest â Novelty â Challenge â Urgency â Passion). ĐŃĐŸ ĐżŃаĐșŃĐžŃĐ”ŃĐșĐ°Ń ŃŃŃаŃĐ”ĐłĐžŃ ĐŒĐŸŃĐžĐČаŃОО ĐŽĐ»Ń Đ»ŃĐŽĐ”Đč Ń ĐĄĐĐĐ, ŃазŃĐ°Đ±ĐŸŃĐ°ĐœĐœĐ°Ń Đ°ĐŒĐ”ŃĐžĐșĐ°ĐœŃĐșĐžĐŒ ĐżŃĐžŃ ĐžĐ°ŃŃĐŸĐŒ УОлŃŃĐŒĐŸĐŒ ĐĐŸĐŽŃĐŸĐœĐŸĐŒ.ĐŻ ŃĐŸĐ·ĐŽĐ°Đ» ŃŃŃŃĐșĐŸŃĐ·ŃŃĐœŃŃ Đ°ĐŽĐ°ĐżŃаŃĐžŃ ŃŃĐŸĐč ŃŃŃаŃДгОО: ĐĐĐĐŁĐĄ (ĐŃĐ·ĐŸĐČ â ĐĐœŃĐ”ŃĐ”Ń â ĐĐŸĐČĐžĐ·ĐœĐ° â ĐŁĐČлДŃŃĐœĐœĐŸŃŃŃ â ĐĄŃĐŸŃĐœĐŸŃŃŃ). Đ ĐŸŃлОŃОД ĐŸŃ ĐŸŃĐžĐłĐžĐœĐ°Đ»Đ°, ĐŒĐŸŃ ĐČĐ”ŃŃĐžŃ ĐŽĐŸĐżĐŸĐ»ĐœĐ”ĐœĐ°: ĐŽĐ»Ń ĐșĐ°Đ¶ĐŽĐŸĐłĐŸ ĐżŃĐœĐșŃа Ń ŃаĐșжД ŃĐ°Đ·ĐŸĐ±Ńал, ĐșаĐș ĐŸĐœ ŃĐ°Đ±ĐŸŃĐ°Đ”Ń ĐŽĐ»Ń ĐŃĐĄĐĐĐ-ĐŒĐŸĐ·ĐłĐ°. ЧОŃаŃŃ ĐŽĐ°Đ»Đ”Đ” Read more âș
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A former president of Microsoftâs Windows Division has been reminiscing about the lean and efficient coding regime at Microsoft in the 1980s. Read more âș
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In this Saturday edition of Business Insider Today, deputy editor Paige DiFiore recounts how she won her war with the annoyance economy. Read more âș
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Dottie Turnbull left her one-bedroom cottage and bought a narrowboat for about $40,000. Five years later, she says it saves her money every month. Read more âș
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For decades, astronomers have been puzzled by strange âzebra stripeâ patterns in radio waves from the Crab Pulsar â bright bands separated by complete darkness. Now, new research suggests the answer lies in a cosmic tug-of-war between gravity and plasma. The pulsarâs plasma spreads light apart, while gravity bends it back together, creating interference patterns that form the striking stripes. Read more âș
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Scientists have created a new kind of carbon material that could make carbon capture much cheaper and more efficient. By carefully controlling how nitrogen atoms are arranged, they found certain structures capture CO2 better and release it using far less heat. One version works at temperatures below 60 °C, meaning it could run on waste heat instead of costly energy. The discovery offers a powerful new blueprint for next-generation climate... Read more âș
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A new solar breakthrough may overcome a long-standing efficiency barrier. Researchers used a âspin-flipâ metal complex to capture and multiply energy from sunlight through singlet fission. The result reached about 130% efficiency, meaning more energy carriers were produced than photons absorbed. This could lead to much more powerful solar panels in the future. Read more âș
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Scientists have developed a new gene therapy that quiets pain at its source in the brainâwithout the addictive risks of opioids. Using AI to map how pain is processed, they created a targeted âoff switchâ that mimics morphineâs benefits but skips its dangerous side effects. In early tests, it delivered lasting relief without affecting normal sensations. The discovery could mark a major step toward safer, non-addictive pain treatments. Read more âș
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A new holographic storage technique uses light in three dimensions to dramatically increase how much data can be stored. It encodes information throughout a material using amplitude, phase, and polarization, rather than just on a surface. An AI model then reconstructs the data from light patterns, simplifying the process. This could pave the way for faster, denser, and more efficient data storage systems. Read more âș
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Scientists have created a microscopic QR code so tiny it can only be seen with an electron microscopeâsmaller than most bacteria and now officially a world record. But this isnât just about size; itâs about durability. By engraving data into ultra-stable ceramic materials, the team has opened the door to storing information that could last for centuries or even millennia without needing power or maintenance. Read more âș
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Nicotine e-cigarettes may be one of the most effective tools yet for quitting smoking, according to a sweeping review of global research. By analyzing findings from 14 major reviews spanning nearly a decade, researchers found consistent, high-quality evidence showing that nicotine vapes outperform traditional methods like patches, gum, and even behavioral support. While some lower-quality studies produced mixed results, the strongest data clearly favored nicotine e-cigarettes. Read more âș
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What teens eat might matter more for their mental health than previously thought. A sweeping review of nearly 20 studies found that healthier diets are often linked to fewer depressive symptoms, while poor eating habits may go hand in hand with greater psychological distress. Interestingly, focusing on whole dietary patternsânot just individual nutrientsâshowed more consistent benefits, suggesting that overall eating habits could play a meaningful role during this critical stage... Read more âș
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A major new U.S. cholesterol guideline is shifting the focus toward earlier, more personalized prevention of heart disease. It urges people to start screening soonerâsometimes even in childhoodâand highlights the importance of tracking not just LDL (âbadâ) cholesterol but also genetic risk factors like lipoprotein(a). A new, more advanced risk calculator now uses broader health data to better predict heart attack and stroke risk over decades. Read more âș
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After a stroke, the brain may do something surprisingly hopefulâit can ârefreshâ parts of itself. Researchers analyzing brain scans from over 500 stroke survivors found that while the damaged side of the brain appears to age faster, the opposite, unaffected side can actually look younger. This unexpected shift seems to reflect the brainâs effort to rewire itself, strengthening healthy regions to compensate for lost function. Read more âș
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04.04.2026 07:15
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News rating updated: 14:12.
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