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Statins are a cornerstone of heart health, but muscle pain and weakness cause many patients to quit taking them. Scientists have now identified the precise molecular trigger behind these side effects. They found that statins jam open a critical muscle protein, causing a toxic calcium leak. The discovery could lead to safer statins that keep their life-saving benefits without the muscle damage.
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ScienceDaily
Gary Cohn, a former chief economic adviser to Trump, said Americans at the top are seeing "massive wealth" while those at the bottom are "suffering." Read more âș
1,124 fresh
Reports of Bill Gates' connections with Jeffrey Epstein grow more lurid with each dump of documents from the Department of Justice. The latest includes somewhat confusing emails that Epstein may have been drafting on behalf of someone named Boris, who worked at the Bill & Melinda Gates Foundation. The messages claim that Bill contracted an [âŠ] Read more âș
1,119 fresh
Just like buying a new iPhone through Apple's online store, you now select each spec of your new Mac device when purchasing through the website. As first spotted by MacWorld, Apple updated its online configuration tool for purchasing a Mac. Compared to the previous design that allowed you to pick between several prebuilt options, the new configurator lets you choose one spec after another instead. It's not a major difference... Read more âș
815 fresh
The director and creator of Ashes of Creation, the MMORPG brought to life via the $3.2 million donated by almost 20,000 backers in 2017, has quit "in protest" against decisions his board was making that he could "not ethically agree with or carry out". Read more Read more âș
712 fresh
After protests broke out in early January, the Iranian regime shut down the internet, starting the longest blackout in Iranian history. Despite this attempt to stop the protests from spreading, they did not stop. Still, the internet shutdown slowed down the spread of information both inside and outside Iran. Behind the heavily policed borders and [âŠ] Read more âș
436 fresh
A computing enthusiast has assembled one of the most bizarre low-capacity USB drives we have ever seen. Read more âș
340 fresh
Today, in 1982, Intel introduced its âshowstoppingâ 80286 processor. This 16-bit fully x86 software compatible CPU delivered some major performance and architectural advancements over the 8086 and 8088, and would continue to be produced and feature in PC systems well into the 1990s. Read more âș
297
Last year, Apple launched CarPlay Ultra, the long-awaited next-generation version of its CarPlay software system for vehicles. Nearly nine months later, CarPlay Ultra is still limited to Aston Martin's latest luxury vehicles, but that should change fairly soon. In May 2025, Apple said many other vehicle brands planned to offer CarPlay Ultra, including Hyundai, Kia, and Genesis. At the time, it said CarPlay Ultra would begin expanding to more vehicles... Read more âș
294 fresh
Long-time Slashdot reader destinyland writes: Just months after his 20th birthday, Bill Gates had already angered the programmer community," remembers this 50th-anniversary commemoration of Gates' Open Letter to Hobbyists. "As the first home computers began appearing in the 1970s, the world faced a question: Would its software be free?" Gates railed in 1976 that "Most of you steal your software." Gates had coded the operating system for Altair's first home... Read more âș
222 fresh
Xiaomi launched the Pad 8 Pro in China last September, and if you've been wondering whether it will get a global release ever since, we have some great news. The global version of the tablet has been spotted in the Geekbench database with the model number 25091RP04G. That "G" at the end confirms that this is in fact the model meant for markets outside of China. As you can see... Read more âș
202 fresh
A mom shares what it's like raising kids with deeply involved great-grandparents and why she now realizes how rare that bond is. Read more âș
200 fresh
Highguard's launch this week would've probably passed by largely unremarked if it wasn't for its appearance at last year's The Game Awards. Unusually for a game with no prior hype or obvious pedigree, it featured as the show's big "and finally" reveal, immediately subjecting it to intense, and slightly bewildered, scrutiny. After that, even as hard facts on the game remained scarce, it continued to draw scorn, purely for the... Read more âș
181
Charlie Kirk started Turning Point USA to reach college-aged kids he believed were being indoctrinated by liberal universities. His efforts were thoroughly embraced by conservative luminaries, all the way up to President Donald Trump and Vice President JD Vance. But since Kirk was assassinated in September, TPUSAâs popularity has exploded on college campuses with membership [âŠ] Read more âș
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The Ukrainian government has successfully blocked unauthorized Starlink terminals from operating within its borders, stopping Russian drones from using the internet service to strike targets deep within the country. Read more âș
180 fresh
Bitcoinâs sharp weekend drop triggered fresh liquidations, with analyst Eric Crown warning the market may face months of further downside. Read more âș
179 fresh
You drop your microfiber towel midâcar wash. No big deal, right? Think again. Picking it up and using it on your car could be a big mistake. We explain why. Read more âș
179 fresh
PicoIDE is touted as 'an open source IDE/ATAPI drive emulator for vintage computers.' Read more âș
154 fresh
As US-Canada relations grow rocky, Canada is rethinking its economy, its alliances, and its place on the world stage under Mark Carney. Read more âș
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Apple is "exploring" the idea of a foldable iPhone with a "square, clamshell-style" design, according to Bloomberg's Mark Gurman. A so-called "iPhone Flip" â unlikely to be the real name â would compete with devices such as Samsung's Galaxy Z Flip 7 and the modern-day Motorola Razr. The clamshell iPhone would be released at some point after Apple's first foldable iPhone, which is expected to launch in September this year.... Read more âș
133 fresh
An online experiment has Elon Musk believing that we are reaching the âsingularityâ. Is that really true? Read more âș
125 fresh
ScienceDaily
A sweeping scientific review highlights wild blueberries as a standout food for cardiometabolic health. The strongest evidence shows improvements in blood vessel function, with encouraging signs for blood pressure, cholesterol, blood sugar, gut health, and cognition. Researchers suggest these benefits may kick in within hoursâor build over weeksâthanks to the berriesâ unique mix of polyphenols and fiber. Read more âș
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Where your body stores fat may matter just as much as how much you carryâespecially for your brain. Using advanced MRI scans and data from nearly 26,000 people, researchers identified two surprising fat patterns tied to faster brain aging, cognitive decline, and higher neurological disease risk. One involves unusually high fat buildup in the pancreas, even without much liver fat, while the otherâoften called âskinny fatââaffects people who donât appear... Read more âș
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Drinking tea, particularly green tea, is linked to better heart health, improved metabolism, and lower risks of chronic diseases like diabetes and cancer. It may also help protect the brain and preserve muscle strength as people age. However, processed teasâsuch as bottled and bubble varietiesâoften contain sugars and additives that may cancel out these benefits. Moderation and choosing freshly brewed tea appear key. Read more âș
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Scientists studying ancient ocean fossils found that the Arabian Sea was better oxygenated 16 million years ago, even though the planet was warmer than today. Oxygen levels only plunged millions of years later, after the climate cooled, defying expectations. Powerful monsoons and ocean circulation appear to have delayed oxygen loss in this region compared to the Pacific. The discovery suggests future ocean oxygen levels may not follow a simple warming-equals-deoxygenation... Read more âș
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A common parasite long thought to lie dormant is actually much more active and complex. Researchers found that Toxoplasma gondii cysts contain multiple parasite subtypes, not just one sleeping form. Some are primed to reactivate and cause disease, which helps explain why infections are so hard to treat. The discovery could reshape efforts to develop drugs that finally eliminate the parasite for good. Read more âș
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Two decades after a breast cancer vaccine trial, every participant is still aliveâan astonishing result for metastatic disease. Scientists found their immune systems retained long-lasting memory cells primed to recognize cancer. By enhancing a key immune signal called CD27, researchers dramatically improved tumor elimination in lab studies. The findings suggest cancer vaccines may have been missing a crucial ingredient all along. Read more âș
36
Researchers have demonstrated that quantum entanglement can link atoms across space to improve measurement accuracy. By splitting an entangled group of atoms into separate clouds, they were able to measure electromagnetic fields more precisely than before. The technique takes advantage of quantum connections acting at a distance. It could enhance tools such as atomic clocks and gravity sensors. Read more âș
35
Cancer doesnât evolve by pure chaos. Scientists have developed a powerful new method that reveals the hidden rules guiding how cancer cells gain and lose whole chromosomesâmassive genetic shifts that help tumors grow, adapt, and survive treatment. By tracking thousands of individual cells over time, the approach shows which chromosome combinations give cancer an edge and why some tumors become especially resilient. Read more âș
35
Statins are a cornerstone of heart health, but muscle pain and weakness cause many patients to quit taking them. Scientists have now identified the precise molecular trigger behind these side effects. They found that statins jam open a critical muscle protein, causing a toxic calcium leak. The discovery could lead to safer statins that keep their life-saving benefits without the muscle damage. Read more âș
33
Scientists at Mount Sinai have unveiled a bold new way to fight metastatic cancer by turning the tumorâs own defenses against it. Instead of attacking cancer cells head-on, the experimental immunotherapy targets macrophagesâimmune cells that tumors hijack to shield themselves from attack. By eliminating or reprogramming these âbodyguards,â the treatment cracks open the tumorâs protective barrier and allows the immune system to flood in and destroy the cancer. Read more âș
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Most popular sources
Business Insider
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23% 8 |
Tom's Hardware
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22% 8 |
Eurogamer.net
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6% 5 |
The Verge
|
6% 3 |
Vox
|
5% 1 |
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01.02.2026 16:20
Last update: 16:15 EDT.
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