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MIT scientists have achieved the first-ever lab synthesis of verticillin A, a complex fungal compound discovered in 1970. Its delicate structure stalled chemists for decades, despite differing from related molecules by only two atoms. With the synthesis finally complete, researchers created new variants that showed strong activity against a rare pediatric brain cancer. The breakthrough could unlock an entire class of previously unreachable cancer-fighting molecules.
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ScienceDaily
"Life is finite. There is no fighting that — as much as people like to put themselves into ice, hoping that they might wake up in 50 years," Helen Mirren said. Read more ›
881 fresh
If employers want AI to transform work, they should pay attention to history’s technological flops Read more ›
429 fresh
DIY DDR5 is no longer just a concept, but a reality, as modder VIK-on has built his first 32GB stick from scavenged parts. The memory chips came from laptop SODIMMs, while a new PCB and cooler were acquired from China. After flashing custom firmware enabling 6400 MT/s XMP, the entire build put together cost $218. Read more ›
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Bloomberg reports on Amazon listings "automatically generated by an experimental AI tool" for stores that don't sell on Amazon. Bloomberg notes that the listings "didn't always correspond to the correct product", leaving the stores to handle the complaints from angry customers: Between the Christmas and New Year holidays, small shop owners and artisans who had found their products listed on Amazon took to social media to compare notes and warn... Read more ›
258 fresh
"This is about whether the Fed will be able to continue to set interest rates based on evidence and economic conditions," Powell said on Sunday. Read more ›
255 fresh
There was no shortage of high-fashion looks at the 2026 Golden Globes, but some stars, such as Jennifer Lopez, missed the mark with their outfits. Read more ›
157 fresh
An anonymous reader shared this report from CNET: Finland-based IXI Eyewear has raised more than $40 million from investors, including Amazon, to build glasses with adaptive lenses that could dynamically autofocus based on where the person wearing them is looking. In late 2025, the company said it had developed a glasses prototype that weighs just 22 grams. It includes embedded sensors aimed at the wearer's eyes and liquid crystal lenses... Read more ›
149 fresh
President Donald Trump said in a post on Truth Social that Cuba would no longer receive oil or money from Venezuela. Read more ›
146
Julius Bruch spent seven years at McKinsey before founding an AI dementia startup. He shares what made the leap hard — and why consulting helped. Read more ›
106 fresh
An anonymous reader shared this report from It's FOSS: Jenny Guanni Qu, a researcher at [VC fund] Pebblebed, analyzed 125,183 bugs from 20 years of Linux kernel development history (on Git). The findings show that the average bug takes 2.1 years to find. [Though the median is 0.7 years, with the average possibly skewed by "outliers" discovered after years of hiding.] The longest-lived bug, a buffer overflow in networking code,... Read more ›
102 fresh
See the Moon phase expected for January 12, 2025 as well as when the next Full Moon is expected. Read more ›
86 fresh
Trump administration's global influence strategy runs through the AI supply chain. Read more ›
86 fresh
Sgt. Dimko Zhluktenko, a commander of a drone team, told Business Insider what it was like flying in the heavy fog that Russia used to its advantage. Read more ›
74 fresh
Sonia Holland and Erin O'Brien, both 26, pay about $570 a month for their spacious two-bedroom apartment in Guangzhou, China. Read more ›
66 fresh
I married into a family of 10 and learned that forcing a "blended family" made things worse. Living side by side saved us. Read more ›
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Celebrities attended the 2026 Golden Globes on Sunday. Selena Gomez and Colman Domingo were among the best-dressed stars of the night. Read more ›
61 fresh
In October, Walmart partnered with OpenAI to launch a new partnership with ChatGPT. Now, its doing the same with Google's Gemini. Read more ›
59 fresh
A tattoo artist skipped store-bought gifts and gave her family tattoos, creating a meaningful tradition rooted in creativity and trust. Read more ›
55 fresh
Stephen Hutyra was inspired by a Facebook post to build a pub in his backyard. He spent $61,000 and created the space of his dreams. Read more ›
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Gentoo Linux posted its 2025 project retrospective this week. Some interesting details: Mostly because of the continuous attempts to force Copilot usage for our repositories, Gentoo currently considers and plans the migration of our repository mirrors and pull request contributions to Codeberg. Codeberg is a site based on Forgejo, maintained by a non-profit organization, and located in Berlin, Germany. Gentoo continues to host its own primary git, bugs, etc infrastructure... Read more ›
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ScienceDaily
A large review of studies suggests that exercise can ease depression about as effectively as psychological therapy. Compared with antidepressants, exercise showed similar benefits, though the evidence was less certain. Researchers found that light to moderate activity over multiple sessions worked best, with few side effects. While it’s not a cure-all, exercise may be a powerful and accessible tool for many people. Read more ›
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Scientists are uncovering why Brazil may be one of the most important yet underused resources for studying extreme longevity. Its highly diverse population harbors millions of genetic variants missing from standard datasets, including rare changes linked to immune strength and cellular maintenance. Brazilian supercentenarians often remain mentally sharp, survive serious infections, and come from families where multiple members live past 100. Together, they reveal aging not as inevitable decline, but... Read more ›
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Sleep isn’t just about feeling rested—it may be one of the strongest predictors of how long you live. Researchers analyzing nationwide data found that insufficient sleep was more closely tied to shorter life expectancy than diet, exercise, or loneliness. The connection was consistent year after year and across most U.S. states. The takeaway is simple but powerful: getting seven to nine hours of sleep may be one of the best... Read more ›
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Exercise doesn’t just challenge the body; it challenges how the brain interprets effort. Scientists discovered that vibrating tendons before cycling allowed people to push harder without feeling like they were working more. Their muscles and hearts worked overtime, but their sense of strain stayed the same. This brain-body mismatch could one day help make exercise feel less intimidating, especially for people who struggle to stay active. Read more ›
63
A long-running debate over Tamiflu’s safety in children may finally be settled. Researchers found that influenza, not the antiviral medication, was linked to serious neuropsychiatric events like seizures and hallucinations. Even more striking, kids treated with Tamiflu had about half the risk of these events compared to untreated children with the flu. The results suggest the drug may be protective rather than harmful. Read more ›
44
When a huge earthquake struck near Kamchatka, the SWOT satellite captured an unprecedented, high-resolution view of the resulting tsunami as it crossed the Pacific. The data revealed the waves were far more complex and scattered than scientists expected, overturning the idea that large tsunamis travel as a single, stable wave. Ocean sensors confirmed the quake’s rupture was longer than earlier models suggested. Together, the findings could reshape how tsunamis are... Read more ›
42
Scientists have discovered an enormous stream of super-hot gas erupting from a nearby galaxy, driven by a powerful black hole at its center. The jets stretch farther than the galaxy itself and spiral outward in a rare, never-before-seen pattern. NASA’s James Webb Space Telescope pierced through thick dust to reveal this violent outflow. The process is so intense it’s robbing the galaxy of star-forming gas at a staggering rate. Read more ›
37
New research shows gut bacteria can directly influence how the brain develops and functions. When scientists transferred microbes from different primates into mice, the animals’ brains began to resemble those of the original host species. Microbes from large-brained primates boosted brain energy and learning pathways, while others triggered very different patterns. The results suggest gut microbes may have played a hidden role in shaping the human brain—and could influence mental... Read more ›
36
Einstein’s claim that the speed of light is constant has survived more than a century of scrutiny—but scientists are still daring to test it. Some theories of quantum gravity suggest light might behave slightly differently at extreme energies. By tracking ultra-powerful gamma rays from distant cosmic sources, researchers searched for tiny timing differences that could reveal new physics. They found none, but their results tighten the limits by a huge... Read more ›
36
Researchers have built a new platform that produces ultrashort UV-C laser pulses and detects them at room temperature using atom-thin materials. The light flashes last just femtoseconds and can be used to send encoded messages through open space. The system relies on efficient laser generation and highly responsive sensors that scale well for manufacturing. Together, these advances could accelerate the development of next-generation photonic technologies. Read more ›
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Business Insider
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29% 4 |
Tom's Hardware
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24% 4 |
Slashdot
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9% 4 |
The Verge
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5% 1 |
Eurogamer.net
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3% 1 |
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12.01.2026 01:35
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