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Researchers have uncovered the enzyme behind chromothripsis, a chaotic chromosome-shattering event seen in about one in four cancers. The enzyme, N4BP2, breaks apart DNA trapped in tiny cellular structures, unleashing a burst of genetic changes that can help tumors rapidly adapt and resist therapy. Blocking the enzyme dramatically reduced this genomic destruction in cancer cells.
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ScienceDaily
An East Bay apartment complex has been bought at a price that's well below its prior value. Read more ›
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A PG&E Corp. unit has bought a San Jose building in a move to bolster the utility's South Bay operations. Read more ›
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The laugh that arrives before the painful part of a story isn't a sign of healing. It's a social contract, written in real time, that releases the listener from having to respond seriously — a skill learned from people who cou Read more ›
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The best movies on Amazon Prime Video this month include Pretty Lethal, The Bluff, Super 8, The Great Escape, Sinners, and more. Read more ›
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Fully electric vehicles are the new hotness, but hybrids still have their place in the market. Here are some common hybrid battery issues drivers run into. Read more ›
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After Artemis II's astronauts returned to earth, "NASA has Artemis III in its sights," reports the Associated Press: In a mission recently added to the docket for next year, Artemis III's yet-to-be -named astronauts will practice docking their Orion capsule with a lunar lander or two in orbit around Earth. Elon Musk's SpaceX and Jeff Bezos' Blue Origin are racing to have their company's lander ready first. Musk's Starship and... Read more ›
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With the weather starting to warm, you may be feeling the itch to start a new project. One of these tools from Lowe's could be helpful additions for that. Read more ›
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Есть такая штука, как "дисплей покупателя" - это тот самый экран на кассе, где пишут сколько денег вы должны заплатить. И есть такое народное развлечение - делать из этих экранов всякое разное - ну например, "часы или метеостанцию" (с)Фишка тут в том, что можно приобрести их б/у за копейки, и получить при этом винтажный газоразрядный экран, приятного зеленого или синего цвета. Пусть алфавитно-цифровой - для часов этого более чем достаточно.... Read more ›
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Every day, valuables are mislaid at airport security, but their journey doesn't end there. Discover the fate of items that travelers leave behind. Read more ›
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With Google releasing the first Android 17 beta version in February, it's now smartphone manufacturers' turn to kickstart their beta programs. Motorola was one of the first to jump on the bandwagon and is doing so with a longer list of devices compared to last year. In addition to the Motorola Edge (2025), Moto G57 and Moto G57 Power, the list of all Motorola devices has been updated with several... Read more ›
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Tinder now lets you prove you are human by scanning your irises at a physical orb device made by Sam Altman's World. Read more ›
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AI growth could add up to 5 million metric tons of e-waste by 2030, as rapid hardware upgrades and data center expansion increase environmental impact. Read more ›
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I grew up in Australia and now live in Saigon, which means I’ve spent most of my adult life watching people with very different amounts of money move through the same social rooms. Expats who made a fortune in tech sitting at the same restaurant as a Vietnamese grandmother who raised five children on almost ... Read more Read more ›
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A growing wave of “AI doom influencers” is shaping public perception as real-world developments amplify concerns about advanced AI systems. Read more ›
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Luxury appliance brands might not have the same name recognition as more mainstream ones, but they boast high-end finishes (and even higher prices). Read more ›
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Введение: Звучащие кувалдыПредставьте, что вы часто ходите мимо кузницы. Кузнецы бьют молотами по наковальне, и вдруг вы замечаете странную вещь: одни молоты звучат вместе красиво, слитно, а другие — противно, вразнобой. Так, согласно легенде, Пифагор пришёл к открытию, которое положило начало теории музыки . Он принёс молоты в лабораторию и взвесил их. Оказалось, что веса молотов, дающих красивое сочетание (консонанс), соотносятся как простые числа 2:1, 3:2 и 4:3 . Так... Read more ›
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Dalal Street emerged as a founder’s paradise in 2025, with 18 Indian startups listing on the bourses and collectively mopping… Read more ›
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iPhone 18 Pro leak reveals a new Dark Cherry color, offering a premium, muted look similar to Kindle devices, alongside other subtle color options. Read more ›
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Looking for NYT Connections answers and hints? Here's all you need to know to solve today's game, plus my commentary on the puzzles. Read more ›
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ScienceDaily
A major international effort has produced an ultra-precise measurement of the Universe’s expansion rate, confirming it’s faster than early-Universe models predict. By linking multiple distance-measuring techniques, scientists ruled out simple errors as the cause of the discrepancy. The persistent “Hubble tension” now looks more real than ever. It could mean our current model of the cosmos is incomplete. Read more ›
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Mars may be hostile, but it might not be entirely unlivable. In lab experiments, yeast cells survived simulated Martian shock waves and toxic perchlorate salts—two major environmental threats on the Red Planet. Their secret weapon was forming protective molecular clusters that shield critical cellular functions under stress. Without these defenses, survival plummeted, pointing to a potential universal strategy life could use beyond Earth. Read more ›
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A new nanodisc-based platform lets scientists study viral proteins in a form that closely mimics real viruses, revealing how antibodies truly recognize them. This approach uncovered hidden interactions in viruses like HIV and Ebola that traditional methods missed. By recreating the virus’s membrane environment, researchers can better understand how immune defenses work. The technique could speed up the development of more effective vaccines. Read more ›
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Researchers are launching a new project to crack the mystery of aggressive breast cancer, where predicting disease progression remains a major hurdle. By studying how tumors interact with and suppress the immune system, scientists aim to identify new biomarkers that reveal how the cancer evolves. Using real patient samples, the team hopes to turn earlier discoveries into practical clinical tools. The goal: more precise, personalized treatments that can outsmart even... Read more ›
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The first-ever published research on Tinshemet Cave reveals that Neanderthals and Homo sapiens in the mid-Middle Paleolithic Levant not only coexisted but actively interacted, sharing technology, lifestyles, and burial customs. These interactions fostered cultural exchange, social complexity, and behavioral innovations, such as formal burial practices and the symbolic use of ochre for decoration. The findings suggest that human connections, rather than isolation, were key drivers of technological and cultur Read more ›
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A cave in Belgium has revealed unsettling evidence that Neandertals selectively cannibalized outsiders, focusing on women and children. The victims weren’t from the local group and appear to have been treated like prey, with bones butchered for meat and marrow. This suggests the behavior wasn’t ritual, but practical—or possibly linked to intergroup conflict. The discovery paints a darker, more complex picture of Neandertal life during their final millennia. Read more ›
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A new study reveals that popular diabetes and weight-loss drugs like Ozempic and Wegovy may not work as effectively for about 10% of people due to specific genetic variants. These individuals appear to have a puzzling condition called “GLP-1 resistance,” where their bodies produce higher levels of the hormone targeted by these drugs—but don’t respond to it properly. Read more ›
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A newly discovered molecule could reshape the future of weight loss treatments by mimicking the powerful appetite-suppressing effects of drugs like Ozempic — but without many of the unpleasant side effects. Identified using artificial intelligence, this tiny peptide, called BRP, appears to act directly on the brain’s appetite-control center, helping animals eat less and lose fat without nausea or muscle loss. Read more ›
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A twice-yearly injection may soon change how high blood pressure is treated. In a global trial, patients receiving the experimental drug zilebesiran alongside standard therapy saw greater blood pressure reductions than those on standard treatment alone. The drug works by blocking a key liver protein, helping blood vessels relax. Researchers say this long-lasting approach could make it much easier for patients to keep their condition under control. Read more ›
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A colossal “cosmic volcano” has erupted in deep space, as a supermassive black hole in galaxy J1007+3540 roars back to life after nearly 100 million years of silence. Astronomers captured stunning radio images showing fresh jets blasting outward while crashing into the intense pressure of a surrounding galaxy cluster, creating a chaotic, distorted structure stretching nearly a million light-years. Read more ›
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18.04.2026 22:39
Last update: 22:15 EDT.
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