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New research suggests Alzheimer’s may start far earlier than previously thought, driven by a hidden toxic protein in the brain. Scientists found that an experimental drug, NU-9, blocks this early damage in mice and reduces inflammation linked to disease progression. The treatment was given before symptoms appeared, targeting the disease at its earliest stage. Researchers say this approach could reshape how Alzheimer’s is prevented and treated.
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ScienceDaily
The Indie Game Awards has stripped Clair Obscur: Expedition 33 of two major awards, including Game of the Year and Debut Game. This is due to developer Sandfall Interactive's use of generative AI, as reported by Mashable. This looks to be fairly cut and dry. The awards ceremony clearly states in its FAQ that any game that uses generative AI in the development process would be "strictly ineligible" for nominations.... Read more ›
2,439 fresh
An acoustically-optimized power supply that prioritizes silence and efficiency over premium components, delivering impressive thermal performance and modern connectivity at a competitive price point. Read more ›
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Instacart is ending its AI-powered pricing tests, which led some users to see higher prices on certain products than others. "Now, if two families are shopping for the same items, at the same time, from the same store location on Instacart, they see the same prices - period," Instacart writes in a blog post on […] Read more ›
1,357 fresh
The company made 80 times as many reports to the National Center for Missing & Exploited Children during the first six months of 2025 as it did in the same period a year prior. Read more ›
1,297 fresh
In the name of music preservation, pirate group Anna's Archive has scraped 300 TB of data from Spotify's library, representing around 37% of all songs but 99.9% of all listens. It's essentially everything on Spotify packaged into torrents to be distributed illegally, analogous to how the group has made books available for free. Read more ›
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YouTube TV cancellations spiked to the highest level in a year during the Disney blackout. Its rivals also saw surges, however. Read more ›
887 fresh
A group of activists has scraped Spotify's entire library, accessing 256 million rows of track metadata and 86 million audio files totaling roughly 300TB of data. The metadata has been released via Anna's Archive, a search engine for "shadow libraries" that previously focused on books. Spotify described the activists as "anti-copyright extremists who've previously pirated content from YouTube and other platforms" and confirmed it is actively investigating the incident. The... Read more ›
857 fresh
Time-travelling psychological horror game Cronos: The New Dawn is finally getting an additional, easier difficulty mode for people who want less of a gameplay challenge. Read more Read more ›
853 fresh
The latest Powerball jackpot is now at $1.6 billion, marking the end of a big year for lottery prizes. Here's the biggest lottery win in every state. Read more ›
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Before we tell you know what we think, and before we get to what you think, we thought we'd do something a little bit different this as part of our usual end-of-year celebrations. What, we wondered, do the people who actually make the games think? As so we've chatted with the developers behind some of our favourite 2025 releases to find out which new games have resonated most with them... Read more ›
635 fresh
The world's largest asset manager is promoting its underperforming bitcoin fund over higher-fee winners, signaling long-term commitment. Read more ›
613 fresh
Mustafa Suleyman, Microsoft AI's CEO, has described using AI for guidance on life decisions as "something that the world needs." Read more ›
593 fresh
Kate Winslet became"very famous very quickly," after starring in "Titanic" in 1997, and the press was quick to body shame her. Read more ›
574 fresh
Nick Woolsey spent his 20s living in Japan. He figured it would be easier to raise his children back in the States, but now he's returning to Japan. Read more ›
567 fresh
The AI data center build-out, as it currently stands, is dependent on two things: Nvidia chips and borrowed money. Perhaps it was inevitable that people would begin using Nvidia chips to borrow money. As the craze has gone on, I have begun to worry about the weaknesses of the AI data center boom; looking deeper […] Read more ›
551 fresh
New House proposal would exempt some stablecoin payments from capital gains taxes and allow stakers to defer income recognition for up to five years. Read more ›
446 fresh
Italy's Competition Authority (AGCM) has imposed a €98.6 million ($116 million) fine on Apple over its App Tracking Transparency feature. Since the release of iOS 14.5 in April 2021, Apple has required apps to ask for permission before tracking a user's activity across other apps and websites for personalized advertising, as part of a feature named App Tracking Transparency. If a user selects the "Ask App Not to Track" option,... Read more ›
441 fresh
Michael Burry of "The Big Short" fame said the US needs to shift away from "power-hungry" chips, but Nvidia has a "death grip" on the sector. Read more ›
438 fresh
Trump is touting tariff revenues and a shrinking trade deficit as his economic accomplishments ahead or midterms, but economists say it's complicated. Read more ›
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ScienceDaily
A major international review has upended long-held ideas about how top performers are made. By analyzing nearly 35,000 elite achievers across science, music, chess, and sports, researchers found that early stars rarely become adult superstars. Most world-class performers developed slowly and explored multiple fields before specializing. The message is clear: talent grows through variety, not narrow focus. Read more ›
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For years, scientists thought Saturn’s moon Titan hid a global ocean beneath its frozen surface. A new look at Cassini data now suggests something very different: a thick, slushy interior with pockets of liquid water rather than an open sea. A subtle delay in how Titan deforms under Saturn’s gravity revealed this stickier structure. These slushy environments could still be promising places to search for life. Read more ›
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A small tweak to mitochondrial energy production led to big gains in health and longevity. Mice engineered to boost a protein that helps mitochondria work more efficiently lived longer and showed better metabolism, stronger muscles, and healthier fat tissue. Their cells produced more energy while dialing down oxidative stress and inflammation tied to aging. The results hint that improving cellular power output could help slow the aging process itself. Read more ›
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A long-standing physics mystery has been solved with the discovery of emergent photon-like behavior inside a strange quantum material. The finding confirms a true 3D quantum spin liquid and unlocks a new way to study deeply entangled matter. Read more ›
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Researchers have revealed that so-called “junk DNA” contains powerful switches that help control brain cells linked to Alzheimer’s disease. By experimentally testing nearly 1,000 DNA switches in human astrocytes, scientists identified around 150 that truly influence gene activity—many tied to known Alzheimer’s risk genes. The findings help explain why many disease-linked genetic changes sit outside genes themselves. The resulting dataset is now being used to train AI systems to predict... Read more ›
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Long before whales and sharks, enormous marine reptiles dominated the oceans with unmatched power. Scientists have reconstructed a 130-million-year-old marine ecosystem from Colombia and found predators operating at a food-chain level higher than any seen today. The ancient seas were bursting with life, from giant reptiles to rich invertebrate communities. This extreme complexity reveals how intense competition helped drive the evolution of modern marine ecosystems. Read more ›
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A rare tick-borne allergy linked to red meat has now been confirmed as deadly for the first time. A healthy New Jersey man collapsed and died hours after eating beef, with later testing revealing a severe allergic reaction tied to alpha-gal, a sugar spread by Lone Star tick bites. Symptoms often appear hours later, making the condition easy to miss. Researchers warn that growing tick populations could put more people... Read more ›
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Astronomers have detected spacetime itself being dragged and twisted by a spinning black hole for the first time. The discovery, seen during a star’s violent destruction, confirms a prediction made over 100 years ago and reveals new clues about how black holes spin and launch jets. Read more ›
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Researchers have found that fossilized dinosaur eggshells contain a natural clock that can reveal when dinosaurs lived. The technique delivers surprisingly precise ages and could revolutionize how fossil sites around the world are dated. Read more ›
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Giant mosasaurs, once thought to be strictly ocean-dwelling predators, may have spent their final chapter prowling freshwater rivers alongside dinosaurs and crocodiles. A massive tooth found in North Dakota, analyzed using chemical isotope techniques, reveals that some mosasaurs adapted to river systems as seas gradually freshened near the end of the age of dinosaurs. These enormous reptiles, possibly as long as a bus, appear to have hunted near the surface,... Read more ›
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Most popular sources
Business Insider
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27% 3 |
Tom's Hardware
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10% 2 |
TechRadar
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7% 6 |
Slashdot
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7% 3 |
Android Authority
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7% 5 |
| View sources » | |
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22.12.2025 12:10
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