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337 AI finds a surprising monkeypox weak spot that could rewrite vaccines

ScienceDaily
ScienceDaily · 12/12/2025 21:09 EDT

Researchers used AI to pinpoint a little-known monkeypox protein that provokes strong protective antibodies. When the team tested this protein as a vaccine ingredient in mice, it produced a potent immune response. The discovery could lead to simpler, more effective mpox vaccines and therapies. It may also help guide future efforts against smallpox.

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