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Researchers have sequenced the oldest RNA ever recovered, taken from a woolly mammoth frozen for nearly 40,000 years. The RNA reveals which genes were active in its tissues, offering a rare glimpse into its biology and final moments. Surprisingly, the team also identified ancient microRNAs and rare mutations that confirm their mammoth origin. The finding shows that RNA can endure millennia—reshaping how scientists study extinct species.
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Gen Z, driven by a desire for social connection, is bringing back a divisive dining trend: shared tables and communal dining. Read more ›
2,080 fresh
Studies show that people who commit mass shootings aren't more likely to be taking antidepressants. But is RFK Jr. paying any attention? Read more ›
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The publisher of Wolfenstein 3D has recalled the struggle to distribute copies of this seminal FPS game in Germany back in the early 1990s. Read more ›
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CEO Noura Sakkijha said the couple sees eye-to-eye about 95% of the time, and they approach disagreements with a Jeff Bezos philosophy. Read more ›
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Usually, I'd start one of these retrospective things with a wiggly line transition to the past for a bit of the old nostalgia-tickling scene-setting. The trouble is, my one overriding memory of Skies of Arcadia is so powerful I can barely remember anything else about the game at all. I can't, for instance, recall where I was when I played it, or even when; and I'm certainly not going to... Read more ›
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"He thought it was a scam, but he still came," Powell, 37, said in his opening monologue. Read more ›
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Universal childcare in New York City is one of Zohran Mamdani's affordability promises. New Mexico's new policy shows that is it possible. Read more ›
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A human AI agent manager may be the future of middle management. Read more ›
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To keep your eyes in the best shape possible, you may want to consider these eye health-boosting supplements. Read more ›
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The White House told America to 'suck it up' on high prices. After Mamdani's win, where affordability was a key issue, Trump is scrambling to reverse. Read more ›
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Six former Amazon employees explain exactly how the layoffs happened, what they did next, and their career plans amid a challenging job market. Read more ›
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I tested the computer maker's rebranded XPS laptop. It's still a good fit for creators as long as you aren't turned off by its peculiar design, hefty weight and high price. Read more ›
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In this Sunday edition of Business Insider Today, we're talking about how the sudden Marriott-Sonder breakup affected employees and customers. Read more ›
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Quiet displays of support for striking Starbucks baristas have begun appearing at the coffee giant's Seattle headquarters. Read more ›
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It's been trying to measure the popularity of programming languages since 2000 using metrics like the number of engineers, courses, and third-party vendors. And "The November 2025 TIOBE Index brings another twist below Python's familiar lead," writes TechRepublic. "C solidifies its position as runner-up, C++ and Java lose some ground, and C# moves sharply upward, narrowing the gap with Java to less than a percentage point..." TIO CEO Paul Jansen... Read more ›
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The same pulling force that causes “tears” in a glass of wine also shapes embryos. It’s another example of how genes exploit mechanical forces for growth and development. Read more ›
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Mamdani's call to boycott Starbucks amid the strike represents an early indication of how he may use the bully pulpit as NYC mayor. Read more ›
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It feels like everyone’s mad at billionaires right now. Maybe it’s the disconnect between Americans struggling with grocery prices and health care premiums and the ultrarich sailing on their super yachts and flying on their private jets. Maybe it’s that Elon Musk is on course to become the world’s first trillionaire. Maybe it’s that billionaires […] Read more ›
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"There's no reason at all to reach inside your pocket and start an eBay business when we can turn these items that we have inside our house into cash." Read more ›
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GLP-1 drugs such as Ozempic and Wegovy may extend the lives of colon cancer patients, according to a major UC San Diego study. Patients on the medications had less than half the mortality rate of non-users. Researchers suspect the drugs’ anti-inflammatory and metabolic effects contribute to improved outcomes. They’re now calling for clinical trials to test whether these findings reflect a true anti-cancer mechanism. Read more ›
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Researchers in Osaka have found that stem cells from fat tissue can repair spinal fractures similar to those caused by osteoporosis. By turning these cells into bone-forming clusters and pairing them with a bone-rebuilding material, rats regained stronger, healthier spines. The approach could offer a safe, minimally invasive alternative for treating bone diseases in humans. Read more ›
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Intermountain Health researchers discovered that customizing vitamin D3 doses for heart attack survivors slashed their risk of another heart attack by 50%. The strategy involved frequent monitoring and dose adjustments to reach ideal vitamin D levels. Traditional studies didn’t track blood levels, missing this critical link. Read more ›
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Researchers uncovered how fatty molecules called ceramides trigger acute kidney injury by damaging the mitochondria that power kidney cells. By altering ceramide metabolism or using a new drug candidate, the team was able to protect mitochondrial function and completely prevent kidney injury in mice. Read more ›
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Exercise appears to spark a whole-body anti-aging cascade, and scientists have now mapped out how it happens—and how a simple oral compound can mimic it. By following volunteers through rest, intense workouts, and endurance training, researchers found that the kidneys act as the hidden command center, flooding the body with a metabolite called betaine that restores balance, rejuvenates immune cells, and cools inflammation. Even more striking, giving betaine on its... Read more ›
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In a first-of-its-kind study, scientists found that bumblebees can tell the difference between short and long light flashes, much like recognizing Morse code. The insects learned which signal led to a sweet reward, demonstrating an unexpected sense of timing. This ability may stem from a fundamental neural process, suggesting that even tiny brains have complex time-tracking mechanisms relevant to evolution and AI. Read more ›
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Researchers have designed a smart drug that hunts down and breaks a little-known RNA that cancer cells depend on. The drug recognizes a unique fold in the RNA and triggers the cell to destroy it. Tests showed that removing this RNA slows cancer growth. The approach could lead to new treatments that attack cancer at its most fundamental level. Read more ›
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New research finds that daily coffee drinking may cut AFib risk by nearly 40%, defying decades of medical caution. Scientists discovered that caffeine’s effects on activity, blood pressure, and inflammation could all contribute to a healthier heart rhythm. The DECAF clinical trial’s findings suggest coffee could be not only safe but beneficial for people with A-Fib. Read more ›
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Researchers discovered that continents don’t just split at the surface—they also peel from below, feeding volcanic activity in the oceans. Simulations reveal that slow mantle waves strip continental roots and push them deep into the oceanic mantle. Data from the Indian Ocean confirms this hidden recycling process, which can last tens of millions of years. Read more ›
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Researchers have discovered that prostate cancer depends on two key enzymes, PDIA1 and PDIA5, to survive and resist therapy. When blocked, these enzymes cause the androgen receptor to collapse, killing cancer cells and enhancing the effects of drugs like enzalutamide. They also disrupt the cancer’s energy system, striking it on multiple fronts. This breakthrough could open a new path to overcoming drug resistance in advanced prostate cancer. Read more ›
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16.11.2025 07:54
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