25 place 14 fresh

92 Stanford makes stem cell transplants safer without chemo

ScienceDaily
ScienceDaily 3 place · 11/07/2025 22:28 EDT

A Stanford-led team has replaced toxic pre-transplant chemotherapy with a targeted antibody, allowing children with Fanconi anemia to receive stem cell transplants safely. The antibody, briquilimab, removes diseased stem cells without radiation, enabling nearly complete donor cell replacement. The approach also widens donor eligibility and could soon be applied to other bone marrow failure diseases.

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