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Generalized anxiety disorder affects millions, often trapping sufferers in cycles of fear and isolation that conventional medications barely relieve. At UCSF, neuroscientist Jennifer Mitchell is testing a pharmaceutical form of LSD called MM120, which has shown striking results in reducing symptoms by promoting neuroplasticity and easing rigid thought patterns. In clinical trials, a single dose significantly outperformed standard treatments, offering hope to those who have found little relief elsewhere.
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A widespread Cloudflare outage disrupted major parts of the internet on Tuesday, knocking many crypto platforms offline. Read more ›
5,003 fresh
If you're experiencing internet issues this morning, you're far from alone. Infrastructure company Cloudflare has been hit with what it calls "widespread 500 errors, [with] Dashboard and API also failing." The company said that services are starting recover, but customers may continue to see "higher-than-normal errors rates" is it continues to work on the problem. Cloudflare is a key internet hub, as it provides network and security products for internet... Read more ›
3,734 fresh
As an American living in Italy but still working with US clients, I wish someone warned me how much exchange rates could impact my life and budget. Read more ›
3,617 fresh
San Francisco-based company blames incident on ‘spike in unusual traffic’ to one of its services Read more ›
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Cloudflare confirmed that an "internal service degradation" was causing issues for users across the internet. Read more ›
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Phelan said it's hard to entice workers for hard jobs like welding when the pay is comparable to a job at a Buc-ees truck stop or a job at Amazon. Read more ›
1,456 fresh
Microsoft's Azure cloud has mitigated the largest DDoS attack in history at close to 16 Tbps from the Aisuru botnet. At its peak, the attack used over 500,000 connected devices to hit the Azure servers with over 3.6 million packets per second to target a single cloud endpoint in Australia. Read more ›
1,092 fresh
Elon Musk claims Tesla may need 100 – 200 billion AI chips per year, a volume far beyond what TSMC and Samsung can supply, which is why he is considering building Tesla's own fab, as he believes existing foundries cannot scale fast enough for him. Read more ›
1,064 fresh
Logitech has confirmed it was breached internally, likely by the Clop gang, who stole terabytes worth of data, not including any sensitive information. Logitech was targeted for extortion through a zero-day security flaw suspected to be found in Oracle's E-Business Suite, which has since been patched. Read more ›
1,031 fresh
Software group behind TurboTax and Credit Karma will pay AI start-up to use its technology Read more ›
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Sony is cutting the price of its PS5 consoles by $100 for Black Friday. Deals include a PS5 Digital Edition 825GB Fortnite bundle for $399.99 and a 1TB PS5 Fortnite bundle for $449.99 — both ship with exclusive Fortnite in-game content and 1,000 V-Bucks. While the Fortnite bundles shave $100 off the regular price of […] Read more ›
953 fresh
For months, the Social Security Administration was quietly sharing sensitive data about immigrants with DHS. Now it’s official. Read more ›
930 fresh
As part of the latest Windows Insider Build, a new experimental feature called "agentic features" has been added, allowing AI agents to create Agent Workspaces that perform tasks and read files. Microsoft says it's secure because these spaces have their own runtime, desktop and permissions. Read more ›
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Thanksgiving is next week. If you're hosting, here's how AI could help you plan the menu. Read more ›
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Tehran is running out of water. Rationing has begun in Iran’s capital city, with some of the approximately 10 million residents experiencing “nightly pressure cuts” between midnight and 5 am. The entire country is in an unprecedented drought, facing its driest — and hottest — autumn in nearly 60 years. Tehran has received no rain […] Read more ›
602 fresh
Sitting at a desk for hours? Upgrade your WFH setup and work in style with these comfy WIRED-tested seats. Read more ›
510 fresh
Apple today shared its annual Apple Podcasts Top Charts of 2025, highlighting the most popular shows, episodes, and listening trends of the year. The 2025 charts are now available in the New tab of the Apple Podcasts app and will remain accessible through the end of the year. Listeners in more than 15 countries will also see a curated Best Shows of 2025 selection chosen by its editorial team. Apple... Read more ›
508 fresh
GLP-1 drugs such as Ozempic and Wegovy may extend the lives of colon cancer patients, according to a major UC San Diego study. Patients on the medications had less than half the mortality rate of non-users. Researchers suspect the drugs’ anti-inflammatory and metabolic effects contribute to improved outcomes. They’re now calling for clinical trials to test whether these findings reflect a true anti-cancer mechanism. Read more ›
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Researchers found that tau proteins don’t jump straight into forming Alzheimer’s-associated fibrils—first they assemble into soft, reversible clusters. When the clusters were dissolved, fibril growth was almost entirely suppressed. This reveals a promising new strategy: stop the precursors, stop the disease. Read more ›
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Researchers uncovered how fatty molecules called ceramides trigger acute kidney injury by damaging the mitochondria that power kidney cells. By altering ceramide metabolism or using a new drug candidate, the team was able to protect mitochondrial function and completely prevent kidney injury in mice. Read more ›
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Exercise appears to spark a whole-body anti-aging cascade, and scientists have now mapped out how it happens—and how a simple oral compound can mimic it. By following volunteers through rest, intense workouts, and endurance training, researchers found that the kidneys act as the hidden command center, flooding the body with a metabolite called betaine that restores balance, rejuvenates immune cells, and cools inflammation. Even more striking, giving betaine on its... Read more ›
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In a first-of-its-kind study, scientists found that bumblebees can tell the difference between short and long light flashes, much like recognizing Morse code. The insects learned which signal led to a sweet reward, demonstrating an unexpected sense of timing. This ability may stem from a fundamental neural process, suggesting that even tiny brains have complex time-tracking mechanisms relevant to evolution and AI. Read more ›
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Researchers have designed a smart drug that hunts down and breaks a little-known RNA that cancer cells depend on. The drug recognizes a unique fold in the RNA and triggers the cell to destroy it. Tests showed that removing this RNA slows cancer growth. The approach could lead to new treatments that attack cancer at its most fundamental level. Read more ›
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Researchers discovered that continents don’t just split at the surface—they also peel from below, feeding volcanic activity in the oceans. Simulations reveal that slow mantle waves strip continental roots and push them deep into the oceanic mantle. Data from the Indian Ocean confirms this hidden recycling process, which can last tens of millions of years. Read more ›
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Electrons can freeze into strange geometric crystals and then melt back into liquid-like motion under the right quantum conditions. Researchers identified how to tune these transitions and even discovered a bizarre “pinball” state where some electrons stay locked in place while others dart around freely. Their simulations help explain how these phases form and how they might be harnessed for advanced quantum technologies. Read more ›
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Scientists in Seoul have uncovered 15 gut bacterial species linked to coronary artery disease, showing that microbes can influence heart health far beyond digestion. Their findings reveal how shifts in gut microbial function — including inflammation, loss of protective species, and overactive metabolic pathways — may drive disease progression. Intriguingly, even “good” bacteria like Faecalibacterium prausnitzii and Akkermansia muciniphila can become harmful under certain conditions. Read more ›
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Historians have traced myths about the Black Death’s rapid journey across Asia to one 14th-century poem by Ibn al-Wardi. His imaginative maqāma, never meant as fact, became the foundation for centuries of misinformation about how the plague spread. The new study exposes how fiction blurred with history and highlights how creative writing helped medieval societies process catastrophe. Read more ›
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18.11.2025 09:25
Last update: 09:20 EDT.
News rating updated: 16:22.
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