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UMass Amherst researchers have developed a groundbreaking nanoparticle-based cancer vaccine that prevented melanoma, pancreatic, and triple-negative breast cancers in mice—with up to 88% remaining tumor-free. The vaccine triggers a multi-pathway immune response, producing powerful T-cell activation and long-term immune memory that stops both tumor growth and metastasis. By combining cancer-specific antigens with a lipid nanoparticle “super adjuvant,” it overcomes key challenges in cancer immunotherapy.
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ScienceDaily
An intern in Shanghai who won an RTX 5060 while attending an Nvidia Roadshow event unexpectedly found himself at a crossroads with his own company. Since it was won on a business trip paid for by the company, the firm demanded the 5060 be handed in. Eventually, the employee resigned after HR subtly told him to find a new job, refusing to give up the GPU in the process. Read more ›
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Trump says that $2,000 tariff checks are coming mid-2026. His GOP allies on Capitol Hill aren't so sure. Read more ›
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For two years, Cook County residents who participated in its basic income piot received $500 no-strings-attached monthly payments. Read more ›
127 fresh
George R.R. Martin teases the 'Game of Thrones' universe will finally get to the world after the OG show's divisive finale. Read more ›
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Microsoft will not release a diversity and inclusion report for 2025 like it has been doing every year since 2019, Stephen Totilo from Game File has reported. Totilo asked the company if it was skipping this year after it failed to publish a report from October to early November like it had done so the previous years. “We are not doing a traditional report this year as we’ve evolved beyond... Read more ›
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The 'Hunger Games' movies have still got it, because the 'Sunrise on the Reaping' trailer was Lionsgate's second-biggest ever. Read more ›
103 fresh
Here's the answer for "Wordle" #1617 on November 23 as well as a few hints, tips, and clues to help you solve it yourself. Read more ›
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We rounded up every Miss Universe and figured out which countries have produced the most titleholders since 1952. Read more ›
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This Microsoft Office 2024 Home and Business license works on both Mac and PCs, and it's now on sale for just $169.97 (reg. $249.99). Read more ›
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An anonymous reader shared this report from CNN: The universe's expansion might not be accelerating but slowing down, a new study suggests. If confirmed, the finding would upend decades of established astronomical assumptions and rewrite our understanding of dark energy, the elusive force that counters the inward pull of gravity in our universe... Last year, a consortium of hundreds of researchers using data from the Dark Energy Spectroscopic Instrument (DESI)... Read more ›
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Meta "is testing a new product that would give Facebook users a personalized daily briefing powered by the company's generative AI technology" reports the Washington Post. They cite records they've reviwed showing that Meta "would analyze Facebook content and external sources to push custom updates to its users." The company plans to test the product with a small group of Facebook users in select cities such as New York and... Read more ›
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Large language models (LLMs) have astounded the world with their capabilities, yet they remain plagued by unpredictability and hallucinations – confidently outputting incorrect information. In high-stakes domains like finance, medicine or autonomous systems, such unreliability is unacceptable. Enter Lean4, an open-source programming language and interactive theorem prover becoming a key tool to inject rigor and certainty into AI systems. By leveraging formal verification, Lean4 promises to make AI safer, mo Read more ›
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In a triumphant election-night speech earlier this month, New York City Mayor-elect Zohran Mamdani addressed Donald Trump directly, telling the president to “Turn the volume up.” Trump has repeatedly called Mamdani a “Communist” and questioned his citizenship status. But when the two met in the Oval Office on Friday, it was all strikingly cordial — […] Read more ›
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The U.S. government is looking into Bitmain to see whether its products pose a risk to its national security. Read more ›
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The California DMV has approved Waymo’s request to conduct driverless testing and to deploy its robotaxis in more locations in the state. As CBS News reports, Waymo now has the permission to operate across the whole Bay Area, Sacramento and most of Southern California up to the border of Mexico. It’s a huge expansion, based on the maps the state DMV has provided. In the images below, you’ll see Waymo’s... Read more ›
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The grid hits Sin City, with Lando Norris looking to extend his lead at the top of the Drivers' Championship. Read more ›
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Consumers chose better value and superior performance over slim new design of Air model Read more ›
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ScienceDaily
Researchers discovered that the common amino acid arginine can block harmful Aβ aggregation and reduce its toxic effects in Alzheimer’s disease models. In flies and mice, oral arginine lowered plaque levels, reduced inflammation, and improved behavior. Its strong safety record and low cost make it a promising repurposing candidate. The findings hint at a surprisingly simple path toward more accessible AD therapies. Read more ›
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Rutgers scientists found that metformin can blunt many of the metabolic and cardiovascular improvements normally produced by exercise. Participants who took the drug saw reduced gains in fitness, blood vessel function, and glucose control. The interference may stem from how metformin affects mitochondrial activity. Read more ›
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Older adults who regularly listen to or play music appear to have significantly lower risks of dementia and cognitive decline. The data suggests that musical engagement could be a powerful, enjoyable tool for supporting cognitive resilience in aging. Read more ›
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Chronic kidney disease has surged to nearly 800 million cases and is now among the top causes of death worldwide. The condition is heavily linked to diabetes, hypertension, and obesity, and often goes unnoticed until late stages. Many countries lack access to dialysis and transplants, leaving millions without adequate care. Read more ›
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Electrons can freeze into strange geometric crystals and then melt back into liquid-like motion under the right quantum conditions. Researchers identified how to tune these transitions and even discovered a bizarre “pinball” state where some electrons stay locked in place while others dart around freely. Their simulations help explain how these phases form and how they might be harnessed for advanced quantum technologies. Read more ›
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Scientists discovered that alcohol activates a sugar-producing pathway in the body, creating fructose that may reinforce addictive drinking. The enzyme responsible, KHK, appears to drive both alcohol cravings and liver injury. When this enzyme was blocked in mice, their drinking decreased and their livers showed far less damage. Read more ›
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GLP-1 drugs like tirzepatide and semaglutide offer powerful weight-loss effects but come with unanswered questions about long-term safety, side effects, and global accessibility. Researchers stress the need for independent studies before these treatments can be fully embraced worldwide. Read more ›
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People are more likely to believe lies when there’s the possibility of a reward. Neuroimaging shows that the brain shifts into reward or risk mode depending on whether the context involves a gain or a loss. Friends show synchronized brain activity that can predict successful deception. Social bonds and incentives can subtly warp how we judge honesty. Read more ›
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Ultra-processed foods, already known for their links to health problems in adults, are now shown to harm young adults too, disrupting blood sugar regulation long before illness appears. A four-year USC study following 85 participants found that even modest increases in UPF consumption drove up the risk of prediabetes and insulin resistance, two early markers that pave the way for type 2 diabetes. Read more ›
31
Penn State scientists identified a striking rise in melanoma across several Pennsylvania counties dominated by cropland and herbicide use. The elevated risk persisted even after factoring in sunlight, suggesting an environmental influence beyond the usual expectations. Researchers warn that drifting chemicals may expose nearby residents, not just farm workers. Read more ›
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Business Insider
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27% 0 |
Tom's Hardware
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26% 21 |
Gizmodo
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7% 3 |
Engadget
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6% 1 |
Slashdot
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5% 1 |
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23.11.2025 00:24
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