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Scientists have uncovered how exercise suppresses appetite through a surprising molecular pathway. A compound called Lac-Phe, produced during intense workouts, directly quiets hunger neurons in the brain while boosting appetite-suppressing ones, causing mice to eat less without side effects. This discovery reveals a natural mechanism linking physical activity and reduced hunger, paving the way for new obesity treatments.
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ScienceDaily
Trump announced in an executive order on Friday a new $100,000 fee for H-1B visa holders. Here's who the new rules will impact. Read more ›
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The Trump administration said on Friday that it would raise application fees for the H-1B visa. Read more ›
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There is a deep human impulse to whittle reality down into familiar and self-flattering fairy tales. We all gravitate toward information that validates our preconceptions and vindicates our in-groups. It is cognitively taxing to revise one’s model of the world. And it is emotionally uncomfortable to recognize fault in our allies or merit in our […] Read more ›
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According to a report by The Washington Post, scientists with the Environmental Protection Agency's Office of Water were told by "political appointees" to stop work on studies that were headed for publication, as they'll now be "subject to a new review process." Staffers were reportedly given the instructions in a town hall meeting this week. The only papers exempt are those for which "scientific journals had already returned proofs —... Read more ›
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Amazon, Microsoft, JPMorgan, and Meta employees on H-1B visas were told to stay put, per employees and communications reviewed by Business Insider. Read more ›
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Stellar Blade developer Shift Up has dropped a mysterious image onto social media, leading some fans to speculate it could be teasing a horror event or even crossover promotion with the upcoming release of Konami's horror, Silent Hill f. Read more Read more ›
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Stan Lee has been dead for nearly a decade, but next week's comic convention will let you chat with his AI recreation, which is...a choice. Read more ›
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Mangione filed a 114-page legal attack on the death penalty and US Attorney General Pam Bondi. He is charged in the murder of UHC CEO Brian Thompson. Read more ›
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From a disastrous AMA on Monday to disappointing Legion Go 2 preorder customers on Friday, the Lenovo team is having a hell of a week. To kick things off, the Lenovo Legion team hosted an AMA on Reddit revolving around its gaming handheld launch. The Legion Go 2 generated a ton of hype, being Lenovo's next-gen gaming handheld with more powerful specs and a higher price tag, but the team... Read more ›
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Welcome, Weekenders! In this newsletter:• The Big Read: Musk’s Memphis supercomputer fixer • The Arena: The highlightification of sports. • The Top 5: Tech elites turn to luxury matchmakers to find love.• Plus, our Recommendations: “Home Cooking,” “The World’s Worst Best” and “Three Days of the Condor.” It definitely wasn’t the opening question Carlos Alcaraz was expecting.As I sat four feet from the world no. 1 tennis player—and full disclosure,... Read more ›
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Fast Company ran a contrarian take about AI from entrepreneur/thought leader Faisal Hoque, who argues there's three AI bubbles. The first is a classic speculative bubble, with asset prices soaring above their fundamental values (like the 17th century's Dutch "tulip mania"). "The chances of this not being a bubble are between slim and none..." Second, AI is also arguably in what we might call an infrastructure bubble, with huge amounts... Read more ›
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Starting Monday, the US government will get another crack at convincing a federal judge to break up Google, after a different judge decided to keep it intact despite finding it to be a monopolist. Lawyers for Google and the Justice Department will return to a federal courthouse in Alexandria, VA for a roughly two-week trial […] Read more ›
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It's not too early to shop for Advent calendars -- this year's latest and greatest are already selling fast. We've hand-picked our favorites, featuring beloved characters, super fun toys and yummy treats for kiddos. Read more ›
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Apple just launched the AirPods Pro 3, and today Amazon introduced the first discount on the earbuds at $10 off their original price. You can get the AirPods Pro 3 for $239.00 on Amazon, down from $249.00. Note: MacRumors is an affiliate partner with Amazon. When you click a link and make a purchase, we may receive a small payment, which helps us keep the site running. Although not a... Read more ›
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President Donald Trump signed an executive order that changed the annual H1-B visa fee. Read more ›
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Meta CEO Mark Zuckerberg claims anyone not wearing smart glasses will be at a “cognitive disadvantage” in the future. But you'll have to pay a hefty social price for those added smarts. Read more ›
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As an American, I'm used to high healthcare costs. When I moved to Colombia and had a C-section, it shockingly cost just $123 — with a private room. Read more ›
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President Donald Trump has signed a new executive order, which adds a $100,000 fee to H-1B visa applications. It's not a one-time fee either: Companies will have to pay $100,000 a year for any employee it brings over to the US on the visa for up to six years. The Secretary of Homeland Security will restrict approval for visa applications unless accompanied by the fee, though the rule "allows case-by-case... Read more ›
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ScienceDaily
Scientists in Zurich have shown that stem cell transplants can reverse stroke damage by regenerating neurons, restoring motor functions, and even repairing blood vessels. The breakthrough not only healed mice with stroke-related impairments but also suggested that treatments could soon be adapted for humans, marking a hopeful step toward tackling one of the world’s most devastating conditions. Read more ›
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New research from Denmark challenges long-held assumptions about body weight and health, revealing that being overweight—or even moderately obese—does not necessarily increase the risk of death compared to those at the upper end of the "normal" BMI range. In fact, those who are underweight or at the lower end of the so-called healthy spectrum faced higher risks. Read more ›
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A massive Danish study reveals that despite the remarkable weight-loss benefits of semaglutide, more than half of adults without diabetes stop using it within a year. High costs, unpleasant side effects, and underlying medical or psychiatric conditions play major roles in the dropouts. Younger users and men are especially prone to quitting, raising concerns since discontinuation often leads to weight regain. Read more ›
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Sweetpotato, a critical food crop for millions, has finally had its genetic code fully decoded after decades of mystery. Scientists unraveled its extraordinarily complex genome of six chromosome sets, revealing a hybrid origin stitched together from multiple wild ancestors. This achievement not only sheds light on sweetpotato’s remarkable adaptability and resilience but also provides powerful tools for breeders to create higher-yielding, more nutritious, and climate-resistant varieties. Read more ›
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Warming Arctic permafrost is unlocking toxic metals, turning Alaska’s once-clear rivers into orange, acid-laced streams. The shift, eerily similar to mine pollution but entirely natural, threatens fish, ecosystems, and communities that depend on them—with no way to stop the process once it starts. Read more ›
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Nitazenes, a powerful and largely hidden class of synthetic opioids, are quickly becoming a deadly factor in the overdose crisis. Over 20 times stronger than fentanyl, these drugs often go undetected on routine drug tests, making overdoses harder to diagnose and reverse. Cases from Tennessee reveal a disturbing pattern of fatalities, with nitazenes frequently mixed into counterfeit pills alongside fentanyl and methamphetamine. Read more ›
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Scientists at Harvard have discovered how salts like lithium bromide break down tough proteins such as keratin—not by attacking the proteins directly, but by altering the surrounding water structure. This breakthrough opens the door to a cleaner, more sustainable way to recycle wool, feathers, and hair into valuable materials, potentially replacing plastics and fueling new industries. Read more ›
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Chronic insomnia may do more than leave you groggy, it could speed up brain aging. A large Mayo Clinic study found that people with long-term sleep troubles were 40% more likely to develop dementia or cognitive impairment, with brain scans showing changes linked to Alzheimer’s. Those reporting reduced sleep showed declines comparable to being four years older, while certain genetic risk carriers saw even steeper drops. Read more ›
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Microplastics have been detected in human blood, brain tissue, and even bones, where they may weaken skeletal structure and accelerate cell aging. Recent studies suggest that these particles could worsen metabolic bone diseases like osteoporosis, a risk that’s especially concerning as fractures are projected to rise sharply in the coming decades. Read more ›
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A massive study of over 4 million adults has revealed that cannabis use may nearly quadruple the risk of developing diabetes. Despite some earlier suggestions that cannabis might have metabolic benefits, this large analysis found significantly higher diabetes rates among users, even after adjusting for other health factors. Read more ›
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Most popular sources
Business Insider
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40% 5 |
Gizmodo
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11% 2 |
Vox
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9% 5 |
Wired
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7% 0 |
Engadget
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5% 4 |
| View sources » | |
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20.09.2025 16:01
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News rating updated: 22:51.
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