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Scientists have uncovered how exercise suppresses appetite through a surprising molecular pathway. A compound called Lac-Phe, produced during intense workouts, directly quiets hunger neurons in the brain while boosting appetite-suppressing ones, causing mice to eat less without side effects. This discovery reveals a natural mechanism linking physical activity and reduced hunger, paving the way for new obesity treatments.
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ScienceDaily
Signs are continuing to point to some imminent Apple hardware updates, while the company is also making tweaks during beta testing for iOS 26.1, keeping us on our toes for the month of October. This week also saw a look at a likely shakeup of Apple's senior leadership in the coming years, as well as some more rumors about Apple's foldable iPhone expected next year, so read on for all... Read more ›
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The country’s grid operator says shifting from coal to clean power is not only possible but inevitable. The work there could provide a road map for other countries. Read more ›
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Salesforce CEO Marc Benioff, who was once seen as a leading voice for liberal politics in the Bay Area, voiced strong support for President Donald Trump in a new interview with the New York Times and advocated for Trump to send National Guard troops to San Francisco. “We don’t have enough cops, ... Read more ›
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A resident of Tulsa, Oklahoma is facing a potential 20 years in prison, for supplying another individual hundreds of 3D printed gun components. Read more ›
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I prefer using Linux, but upgrading from Windows 10 to Windows 11 was a smooth process. If you are being nagged to upgrade before October 14, then this how to will show just how easy it is. Read more ›
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Vivan Chu, cofounder of Diligent Robotics, told BI how her second child has brought up a "stupid gripe" around access to breast-pumping rooms. Read more ›
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Coros' Nomad is marketed as a "go-anywhere, do-anything" adventure watch. It's got GPS and offline maps and will track a lot of activities, from yoga to bouldering. There's an "Adventure Journal," which the marketing copy promises will help you record "every step, catch, and summit." While it doesn't have some of the bells and whistles […] Read more ›
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The US government shut down 10 days ago, and there's little indication that it will reopen anytime soon. At the center of it all is healthcare. Read more ›
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To enable theme pack support on Android, Google has created a Theme Manager service that builds off Material You. Read more ›
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When I had two babies in one year, I worried about my finances. But thanks to paid sponsorships, I got most products and family trips for free. Read more ›
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We could get new MacBook Pros, MacBook Airs, Mac minis, Mac Studios, and iMacs across the next few months. Read more ›
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These first-generation Americans moved back to the Asia their parents left behind — some seeking opportunity, others career growth, and one, to follow love. Read more ›
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theodp writes: GeekWire reports that Microsoft is bringing artificial intelligence to every public classroom in its home state -- and sparking new questions about its role in education. The Redmond tech giant on Thursday unveiled Microsoft Elevate Washington, a sweeping new initiative that will provide free access to AI-powered software and training for all 295 public school districts and 34 community and technical colleges across Washington state. The program is... Read more ›
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Wende Zomnir is the cofounder of Urban Decay and founder of Caliray. Her sons came to the office after school and are now entrepreneurs themselves. Read more ›
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College delivery robots were once known for being kicked and prodded at by students. Now, they're more common than ever. Read more ›
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Butterfly, The Girlfriend, and The Second Best Hospital in the Galaxy are just a few of the shows you should be watching on Amazon Prime Video this week. Read more ›
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I came late enough to the original Yooka-Laylee that, by the time I was acquainting myself with its titular lizard and bat protagonists, it felt like its more egregious launch issues - its much-criticised camera for one - had already been ironed out. I enjoyed it enough that I wasn't wholly convinced Yooka-Replaylee - a “remastered and enhanced” version of Playtonic's 2017 collectathon throwback - could do enough to warrant... Read more ›
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Bestselling romantasy author Carissa Broadbent says self-publishing can be more lucrative than traditional publishing and give authors more control. Read more ›
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President Trump imposed a 100% tariff on Chinese goods and announced export controls on undefined 'critical software,' a move that could cripple China’s tech and manufacturing sectors more than tariffs themselves. Read more ›
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ScienceDaily
Addiction often isn’t about chasing pleasure—it’s about escaping pain. Researchers at Scripps Research have discovered that a tiny brain region called the paraventricular nucleus of the thalamus (PVT) becomes hyperactive when animals learn that alcohol eases the agony of withdrawal. This circuit helps explain why people relapse: their brains learn that alcohol brings relief from stress and anxiety. Read more ›
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Scientists have pinpointed Y1 receptor neurons in the brain that can override chronic pain signals when survival instincts like hunger or fear take precedence. Acting like a neural switchboard, these cells balance pain with other biological needs. The research could pave the way for personalized treatments that target pain at its brain source—offering hope for millions living with long-term pain. Read more ›
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When cancer cells are physically squeezed, they mount an instant, high-energy defense by rushing mitochondria to the cell nucleus, unleashing a surge of ATP that fuels DNA repair and survival. This newly discovered mechanism, visualized in real time with advanced microscopy, shows mitochondria acting like emergency first responders rather than static power plants. The structures, called NAMs, were also identified in patient tumor biopsies, suggesting real-world relevance to cancer’s spread. Read more ›
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New research reveals that deep-sea mining could dramatically threaten 30 species of sharks, rays, and ghost sharks whose habitats overlap with proposed mining zones. Many of these species, already at risk of extinction, could face increased dangers from seafloor disruptions and sediment plumes caused by mining activity. Read more ›
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Researchers at Columbia have created a chip that turns a single laser into a “frequency comb,” producing dozens of powerful light channels at once. Using a special locking mechanism to clean messy laser light, the team achieved lab-grade precision on a small silicon device. This could drastically improve data center efficiency and fuel innovations in sensing, quantum tech, and LiDAR. Read more ›
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An international team has confirmed that large quantum systems really do obey quantum mechanics. Using Bell’s test across 73 qubits, they proved the presence of genuine quantum correlations that can’t be explained classically. Their results show quantum computers are not just bigger, but more authentically quantum. This opens the door to more secure communication and stronger quantum algorithms. Read more ›
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New research shows green tea may help the body burn fat and balance blood sugar. In a study with obese mice, it improved metabolism and muscle health without harming lean animals. Scientists say its powerful plant compounds work together to regulate fat and energy use. The findings hint that green tea could be a natural support for healthy weight management. Read more ›
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A Penn State research team found that streetlights could double as affordable EV charging stations. After installing 23 units in Kansas City, they discovered these chargers were faster, cheaper, and more eco-friendly than traditional stations. Their AI-based framework also prioritized equity and scalability, making it adaptable for cities across the country. Read more ›
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Researchers have designed a peptide that prevents the deadly misfolding of alpha-synuclein, the protein behind Parkinson’s and some dementias. In lab and animal tests, it stabilized the protein and improved motor function. The work demonstrates the power of rational drug design in tackling brain diseases that have long lacked effective treatments. Read more ›
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Scientists discovered that vitamin D2 supplements can lower levels of vitamin D3, the form the body uses most effectively. Unlike D2, vitamin D3 enhances the immune system’s first line of defense against infections. This raises questions about which type of supplement should be prioritized. Read more ›
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11.10.2025 09:21
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