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Virginia Tech researchers are investigating how overloaded mitochondria in the brain’s memory circuits may spark early Alzheimer’s damage. Their work focuses on calcium signaling and how it might trigger breakdowns in the entorhinal cortex.
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When liberals denounce Donald Trump’s authoritarianism, they often cast his immigration agenda as a case in point. Back in June, Democrats on the House Oversight Committee decried the president’s “mass deportation operations” as the “stepping stone” to his “radical attempts to seize absolute power.” In the same statement, they condemned the administration’s deportation of noncriminal […] Read more ›
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Do I like the ROG Xbox Ally X? Yes. Does it give me those sweet techdorphins you get from using a lovely bit of new kit? Will it replace my Steam Deck? Almost certainly. Is it an Xbox? Hmmm. While writing this I actually paused here to figure out the sound I made after asking myself the question. While I wrote "hmmm", it was more sort of a "tsk" but... Read more ›
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Pallets of RTX 5090 GPUs from MSI had been spotted on Reddit a few days ago, sparking concern and curiosity over export controls. The White House has barred China from receiving most high-end GPUs, so these cards arrived via illegal channels, as MSI clarifies and denies any involvement in a press release. Read more ›
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Tiffany Ng, a Gen Z writer in New York, chained her iPhone to a wall for a week. She said she felt liberated. Read more ›
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Ina Garten's "eggs in purgatory" recipe is deliciously comforting and features store-bought sauce, making it easy (and cheap) to whip up. Read more ›
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The beloved artist, who illustrated iconic posters for 'Star Wars', 'Indiana Jones', 'Back to the Future', and more, was 78. Read more ›
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A new Interbrand study syas tech companies lead the top 10 brands of 2025, with Nvidia and Instagram showing significant growth. Read more ›
426 fresh
The new Moto X70 Air is ultra-thin at 5.99mm, but manages to cram a 4,800mAh battery and Snapdragon 7 Gen 4. Read more ›
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OpenAI has spent roughly $6.4 billion in stock to buy three startups over the last 16 months, while its smaller rival Anthropic has done barely any deals. But Anthropic, recently valued at $170 billion in a funding round, told investment bankers in recent weeks that it is getting ready to move off the sidelines and do more acquisitions, according to people who have spoken to its executives. It is considering... Read more ›
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There’s no shortage of things that could end the world. But between climate change, risks from AI, and biological threats like pandemics, we seem to be forgetting about one human-made existential risk that has been with us for 80 years: the ever-present possibility of nuclear warfare. But nuclear war hasn’t forgotten about us. “Because of […] Read more ›
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Investors are keeping a close eye on potential signs of the AI industry reaching the point of bursting its inflated bubble, as it's revealed that almost half of all the largest companies on the S&P 500 have medium-to-high exposure to AI. The risks associated with the industry collapsing under its own weight are greater than ever. Read more ›
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Having used the Pixel 10 Pro, I can't forgive Google for what it did to the Pixel 9's camera. Read more ›
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YouTube's new video player isn't winning everyone over. What do you think about the redesign? Take our poll and let us know. Read more ›
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The DoJ has seized $15 billion in Bitcoin, thought to be proceeds from a 'pig butchering' scam run from forced-labor compounds in Cambodia. Read more ›
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The reminder experience in Google Keep is changing, and Google Tasks is involved – here's what to expect. Read more ›
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President Donald Trump’s ICE is newly flush with cash and straining to add more officers to its masked ranks. US Immigration and Customs Enforcement is papering social media with recruitment ads, flooding them onto local news stations in so-called sanctuary cities, talking up signing bonuses (up to $50,000 paid out over three years) and student […] Read more ›
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From raw milk to cod liver oil, few of Kennedy's professed alternatives to mainstream medicine pass scientific muster. Read more ›
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A record 2.1 million electric vehicles were sold globally last month, driven by strong demand in the US, Europe, and China. Read more ›
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These rising investment bankers aged 35 and under have had key roles in major mergers, acquisitions, and IPOs. Read more ›
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Scientists identified two types of brain cells, neurons and microglia, that are altered in people with depression. Through genomic mapping of post-mortem brain tissue, they found major differences in gene activity affecting mood and inflammation. The findings reinforce that depression has a clear biological foundation and open new doors for treatment development. Read more ›
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Scientists have pinpointed Y1 receptor neurons in the brain that can override chronic pain signals when survival instincts like hunger or fear take precedence. Acting like a neural switchboard, these cells balance pain with other biological needs. The research could pave the way for personalized treatments that target pain at its brain source—offering hope for millions living with long-term pain. Read more ›
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Researchers at the University of Barcelona found that combining pemafibrate and telmisartan significantly reduces liver fat and cardiovascular risks in MASLD models. The drug duo works better together than alone, likely due to complementary mechanisms. They also uncovered a new role for the PCK1 protein in fat metabolism. Read more ›
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Spanish researchers found that combining a calorie-reduced Mediterranean diet with exercise and professional support cut type 2 diabetes risk by 31%. Participants also lost weight and reduced waist size, proving that small, consistent lifestyle shifts can yield major health gains. Experts say this realistic approach could be integrated globally to tackle diabetes and obesity epidemics. Read more ›
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UMass Amherst researchers have developed a groundbreaking nanoparticle-based cancer vaccine that prevented melanoma, pancreatic, and triple-negative breast cancers in mice—with up to 88% remaining tumor-free. The vaccine triggers a multi-pathway immune response, producing powerful T-cell activation and long-term immune memory that stops both tumor growth and metastasis. By combining cancer-specific antigens with a lipid nanoparticle “super adjuvant,” it overcomes key challenges in cancer immunotherapy. Read more ›
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MIT and Harvard scientists have designed an advanced type of immune cell called a CAR-NK cell that can destroy cancer while avoiding attack from the body’s own immune defenses. This innovation could allow doctors to create “off-the-shelf” cancer treatments ready for use immediately after diagnosis, rather than waiting weeks for personalized cell therapies. Read more ›
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Complex, intelligent life in the galaxy appears vanishingly rare, with the nearest possible civilization perhaps 33,000 light-years distant. Yet despite the odds, scientists insist that continuing the search for extraterrestrial intelligence is essential — for either outcome reshapes our understanding of life itself. Read more ›
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Scientists at UC Irvine have found a way to potentially reverse age-related vision loss by targeting the ELOVL2 “aging gene” and restoring vital fatty acids in the retina. Their experiments in mice show that supplementing with specific polyunsaturated fatty acids, not just DHA, can restore visual function and even reverse cellular aging signs. Read more ›
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Overdose deaths from fentanyl mixed with stimulants have skyrocketed among seniors, increasing 9,000% in just eight years. Once thought to affect mainly the young, the opioid epidemic’s fourth wave now engulfs older adults too. Cocaine and methamphetamine are the leading culprits, and experts warn that multi-drug use makes these overdoses especially lethal. Doctors are urged to educate patients and caregivers on prevention and safer pain management. Read more ›
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New research shows green tea may help the body burn fat and balance blood sugar. In a study with obese mice, it improved metabolism and muscle health without harming lean animals. Scientists say its powerful plant compounds work together to regulate fat and energy use. The findings hint that green tea could be a natural support for healthy weight management. Read more ›
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15.10.2025 10:13
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