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Acetaminophen may be doing more than just dulling pain in your brain it could be stopping it before it even starts. Scientists at Hebrew University have discovered that a metabolite of the drug, AM404, blocks pain signals right at their source by shutting down specific sodium channels in pain-sensing nerves. This radically shifts our understanding of how this common medication works and opens a door to new, more targeted painkillers that might eliminate side effects like numbness or weakness.
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ScienceDaily
There is no evidence the footage was deceptively manipulated, but ambiguities around how the video was processed may further fuel conspiracy theories about Epstein's death. Read more ›
8,183 fresh
If you need to replace your [insert Apple product here], this Amazon Prime Day is a chance to snag it at a significant discount. Read more ›
660 fresh
An image from June shows a scorch mark where a geodesic dome used to be at Al Udeid Air Base in Qatar. Read more ›
642 fresh
The 'Foundation' fan favorite joins an expanding cast of faces familiar and new—including Stockard Channing and Dianne Wiest, who'll reprise their roles from the 1998 film. Read more ›
570 fresh
Season one ended on a poignant note that proved extra-emotional for the Apple TV+ series star. Read more ›
407 fresh
Senior staff at Erebor, a tech-focused banking startup, have worked at Palmer Luckey's family office, in tech startups, and at other banks. Read more ›
397 fresh
Bizarre query results have come up when researchers ask the new chatbot what it's thoughts on Israel are. Read more ›
372 fresh
Apple is working on a set of smart glasses that will rival Meta's popular AI-equipped Ray-Bans, offering many of the same features. Rumors about Apple's work on the glasses have been picking up, and we've gathered all of the information we've heard in the guide below. Overview There have been persistent rumors about Apple's work on augmented reality smart glasses, but true, lightweight augmented reality glasses are still years away.... Read more ›
357 fresh
Ivanka Trump's street style is consistently fashionable, but her looks for political events can be hit or miss. Read more ›
336 fresh
After an extended wait, 'Strange New Worlds' will boldly go once more next week—so here's a reminder of where everything left off. Read more ›
326 fresh
Elon Musk's xAI faced internal backlash after Grok's antisemitic posts. Workers demanded answers — and one said they would quit. Read more ›
322 fresh
The Dollar General is a great place to get items at a bargain, but are the USB cables and chargers worth it? Here's what you need to know before buying. Read more ›
308 fresh
Six Republican Congress members callously urged Canada to take “proper action” to mitigate smoke wafting into the U.S. Read more ›
283 fresh
From the beginning, Elon Musk has marketed Grok, the chatbot integrated into X, as the unwoke AI that would give it to you straight, unlike the competitors. But on X over the last year, Musk’s supporters have repeatedly complained of a problem: Grok is still left-leaning. Ask it if transgender women are women, and it […] Read more ›
271
The US International Trade Commission has determined that Chinese camera company Insta360 has infringed on at least some of GoPro's patents. Based on a press release from GoPro, the determination specifically found that "Insta360 violated federal law by importing and selling in the United States products that infringe GoPro intellectual property." GoPro was particularly "pleased" the ITC's judge found that Insta360 infringed on "a patent covering GoPro's iconic Hero camera... Read more ›
264 fresh
Children's Health Defense says it's illegal for news outlets to "censor" anti-vax garbage. Read more ›
259 fresh
The Social Security administration is moving some workers to do teleservice work and address their most pressing needs. Read more ›
224 fresh
Amazon has already slashed the pricing on several excellent robot vacuums for Prime Day, including high-end hybrid mopping models like the Dreame X40 Ultra and Narwal’s Freo Z Ultra. Thankfully, if a $700 or $800 robovac is out of the question, Tapo’s RV30 Max Plus is an impressive alternative that’s currently on sale at Amazon with […] Read more ›
222 fresh
The fear is that the USPSTF will go the same way as the CDC's vaccine advisory panel. Read more ›
213 fresh
ScienceDaily
Scientists at MIT have turbocharged one of nature’s most sluggish but essential enzymes—rubisco—by applying a cutting-edge evolution technique in living cells. Normally prone to wasteful reactions with oxygen, this revamped bacterial rubisco evolved to work more efficiently in oxygen-rich environments. This leap in enzyme performance could pave the way for improving photosynthesis in plants and, ultimately, increase crop yields. Read more ›
58
Ambroxol, long used for coughs in Europe, stabilized symptoms and brain-damage markers in Parkinson’s dementia patients over 12 months, whereas placebo patients worsened. Those with high-risk genes even saw cognitive gains, hinting at real disease-modifying power. Read more ›
36
Australian scientists have discovered a method to produce ammonia—an essential component in fertilizers—using only air and electricity. By mimicking lightning and channeling that energy through a small device, they’ve bypassed the traditional, fossil fuel-heavy method that’s been used for over a century. This breakthrough could lead to cleaner, cheaper fertilizer and even help power the future, offering a potential alternative fuel source for industries like shipping. Read more ›
27
Feeling jittery as the week kicks off isn’t just a mood—it leaves a biochemical footprint. Researchers tracked thousands of older adults and found those who dread Mondays carry elevated cortisol in their hair for months, a stress echo that may help explain the well-known Monday heart-attack spike. Even retirees aren’t spared, hinting that society’s calendar, not the workplace alone, wires Monday anxiety deep into the HPA axis and, ultimately, cardiovascular... Read more ›
27
A laser-equipped research platform has, for the first time, photographed airflow just millimeters above ocean waves, revealing two simultaneous wind–wave energy-transfer tricks—slow short waves steal power from the breeze, while long giants sculpt the air in reverse. These crisp observations promise to overhaul climate and weather models by clarifying how heat, momentum, and greenhouse gases slip between sea and sky. Read more ›
26
Scientists at UCSF combined advanced brain-network modeling, genetics, and imaging to reveal how tau protein travels through neural highways and how certain genes either accelerate its toxic journey or shield brain regions from damage. Their extended Network Diffusion Model pinpoints four gene categories that govern vulnerability or resilience, reshaping our view of Alzheimer’s progression and spotlighting fresh therapeutic targets. Read more ›
21
Researchers have developed an ultra-thin drumhead-like membrane that lets sound signals, or phonons, travel through it with astonishingly low loss, better than even electronic circuits. These near-lossless vibrations open the door to new ways of transferring information in systems like quantum computers or ultra-sensitive biological sensors. Read more ›
19
When you're mentally exhausted, your brain might be doing more behind the scenes than you think. In a new study using functional MRI, researchers uncovered two key brain regions that activate when people feel cognitively fatigued—regions that appear to weigh the cost of continuing mental effort versus giving up. Surprisingly, participants needed high financial incentives to push through challenging memory tasks, hinting that motivation can override mental fatigue. These insights... Read more ›
17
Scientists at the University of Sydney have uncovered a malfunctioning version of the SOD1 protein that clumps inside brain cells and fuels Parkinson’s disease. In mouse models, restoring the protein’s function with a targeted copper supplement dramatically rescued movement, hinting at a future therapy that could slow or halt the disease in people. Read more ›
15
Long-lost 1960s aerial photos let Copenhagen researchers watch Antarctica’s Wordie Ice Shelf crumble in slow motion. By fusing film with satellites, they discovered warm ocean water, not surface ponds, drives the destruction, and mapped “pinning points” that reveal how far a collapse has progressed. The work shows these break-ups unfold more gradually than feared, yet once the ice “brake” fails, land-based glaciers surge, setting up meters of future sea-level rise... Read more ›
15
Most popular sources
Wired
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32% 21 |
Business Insider
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18% 5 |
Gizmodo
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9% 0 |
Android Authority
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6% 0 |
The Verge
|
6% 3 |
| View sources » | |
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11.07.2025 20:47
Last update: 20:40 EDT.
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