Microbial communities are thought to contain keystone species, which can disproportionately affect the stability of the communities, even if only present in low abundances. Identifying these keystone species can be challenging, especially in the human gut, since it is not feasible to isolate them through systematic elimination. Researchers have designed a new data-driven keystone species identification (DKI) framework that uses machine learning to resolve this difficulty. Read more ›
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A scientists has sulfur on her mind. The yellow element is a vital macronutrient, and she's trying to understand how it cycles through the environment. Specifically, she's curious about the sulfur cycle in Earth's ancient ocean, some 3 billion years ago. Read more ›
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The boiling frog parable seems to have inspired new research, which identified a brain pathway responsible for rapid-threat detection. Read more ›
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Researchers have discovered a 'genomic tug of war' in animal studies that could influence how well certain patients -- or certain cancers -- respond to decitabine, a drug used to treat myelodysplastic syndromes that is plagued by drug resistance issues. For the first time, researchers show that decitabine causes coding and non-coding regions of DNA to engage in a tug of war for a gene activator, called H2A.Z. Typically, deticabine... Read more ›
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A new theoretical model helps explain how epigenetic memories, encoded in chemical modifications of chromatin, are passed from generation to generation.  Within each cell's nucleus, researchers suggest, the 3D folding patterns of its genome determines which parts of the genome will be marked by these chemical modifications. Read more ›
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Researchers take a look at data that has so far been mostly discarded as contamination, revealing the previously underestimated role of extracellular vesicles (EVs). These are important for the exchange of genetic information between cells and thus for the microbial community in the sea. Read more ›
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A team of pioneering researchers has made a significant leap forward in the complex world of molecular chemistry. Their focus? Azaarenes, unique molecular puzzle pieces crucial to many everyday products, from eco-friendly agrochemicals to essential medicines. The team developed an innovative way to modify these molecules using light-powered enzymes -- a groundbreaking discovery that holds promise for new industrially relevant chemical reactions and sustainable energy solutions. Read more ›
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Quiz shows, where contestants answer rapid-fire questions in a high-stress, high-stakes environment, are an integral part of TV programming -- and now they are demonstrating that they have research value, according to a new study. Read more ›
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A new tool, based on topology, makes finding the areas where neural networks are confused as simple as spotting mountaintops from an airplane. The ability to spot and address those areas of confusion should enable more confident application of neural networks in high-stakes decision scenarios or image prediction tasks like healthcare and research. Read more ›
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From heart beats to stomach gurgles, sounds hold important health information. New wireless devices sit on skin to continuously capture these sounds, then stream data to smartphones or tablets in real time. In pilot studies, devices accurately tracked sounds associated with cardiorespiratory function, gastrointestinal activity, swallowing and respiration. The devices are particularly valuable for premature babies, who can experience apneas and gastrointestinal complications, which are accompanied by sounds. Read more ›
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Scientists have grown small blood vessel-like models in the lab and used them to show how damage to the scaffolding that supports these vessels can cause them to leak, leading to conditions such as vascular dementia and stroke. Read more ›
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Researchers have discovered that 'cell competition' following gene therapy results in the accumulation of stem cells with genetic mutations which make them grow faster. Some of these genetic mutations have been previously seen at higher levels in elderly individuals and those with certain blood cancers, such as leukaemia. Read more ›
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Researchers reveal that vitamin B12 significantly boosts the efficiency of cellular reprogramming, thus holding promise for regenerative medicine. Vitamin B12 supplementation shows potential in speeding up tissue repair in a model of ulcerative colitis -- an observation that points to potential new treatments for inflammatory diseases. Read more ›
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Scientists have published new evidence that shows changes in brain network patterns that occur in early-stage Alzheimer's disease differ from those associated with normal aging. The findings also show that the impact of Alzheimer's on brain function is broader than previously believed. In addition to detecting characteristic changes in the brain circuits supporting memory and attention as expected, the researchers found distinct changes in circuits involved in sensory and motor... Read more ›
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Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that affects neurons in the brain and spinal cord causing loss of muscle control. Scientists have now suggested a potential therapeutic strategy to tackle this pathology that has no treatment to date. It is a molecular trap that prevents one of the most common genetic ALS-causing peptide compounds, the Poly-GR dipeptide, from causing its toxic effects in the body. The results show... Read more ›
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Immunotherapies that target the CD20 antigen have revolutionized how patients with a variety of blood cancers and hematologic disorders have been treated. However, many patients develop resistance to these treatments due to a loss of the antigen that's being targeted. Now, a new study has found that gene splicing occurring within these cells can cause significant changes in CD20 protein levels that render the therapies ineffective. Read more ›
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Children whose mothers are highly stressed, anxious or depressed during pregnancy may be at higher risk for mental health and behavior issues during their childhood and teen years, according to new research. Read more ›
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A new study finds that microglia with mutant TREM2 protein reduce brain circuit connections, promote inflammation and contribute to Alzheimer's pathology in other ways. Read more ›
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Common oral infections, periodontal diseases and caries, are associated with inflammatory metabolic profiles related to an increased risk of cardiometabolic diseases, a new study by an international team of researchers suggests. Oral infections also predicted future adverse changes in metabolic profiles. Read more ›
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Many songbirds are nesting earlier in spring because of warmer temperatures brought about by climate change. But the shift brings another danger that is especially deadly for nestlings: greater exposure to temperature variability in the form of cold snaps and heat waves. Read more ›
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25.07.2026 23:31
Last update: 23:05 EDT.
News rating updated: 06:20.
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