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ScienceDaily · 10/01/2024 11:50 EDT

NMR-guided optimization of lipid nanoparticles for enhanced siRNA delivery

siRNA therapies show promise for treating diseases like cancer and genetic disorders, but their effectiveness depends on proper delivery. A recent study found that the method of mixing siRNA with lipid nanoparticles (LNPs) is key to success. Read more ›

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ScienceDaily
ScienceDaily · 10/01/2024 11:50 EDT

Siloxane nanoparticles unlock precise organ targeting for mRNA therapy

Engineers have discovered a simple and inexpensive means of directing lipid nanoparticles (LNPs), the revolutionary molecules that delivered the COVID-19 vaccines, to target specific tissues, presaging a new era in personalized medicine and gene therapy. The key is making small changes to the chemical structure of LNPs, including the incorporation of siloxane, a chemical group that includes silicon, whose wider atomic radius increases membrane flexibility and improves mRNA uptake by... Read more ›

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ScienceDaily
ScienceDaily · 10/01/2024 11:49 EDT

Culprit that turns classical Klebsiella pneumoniae into a devastating, drug-resistant killer

New research has identified the genetic elements responsible for turning classical Klebsiella pneumoniae, which generally infects only sick and/or immunocompromised people in the health care setting, into hypervirulent Klebsiella pneumoniae, which can also infect otherwise healthy people in the community. Read more ›

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ScienceDaily
ScienceDaily · 10/01/2024 11:49 EDT

Stronger together: miniature robots in convoy for endoscopic surgery

Miniature robots on the millimeter scale often lack the strength to transport instruments for endoscopic microsurgery through the body. Scientists are now combining several millimeter-sized TrainBots into one unit and equipping them with improved 'feet'. For the first time, the team was able to perform an electric surgical procedure on a bile duct obstruction experimentally with a robotic convoy. Read more ›

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ScienceDaily
ScienceDaily · 10/01/2024 11:48 EDT

Scientists discover planet orbiting closest single star to our Sun

Astronomers have discovered an exoplanet orbiting Barnard's star, the closest single star to our Sun. On this newly discovered exoplanet, which has at least half the mass of Venus, a year lasts just over three Earth days. The team's observations also hint at the existence of three more exoplanet candidates, in various orbits around the star. Read more ›

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ScienceDaily
ScienceDaily · 10/01/2024 11:48 EDT

Feet first: AI reveals how infants connect with their world

Researchers explored how infants act purposefully by attaching a colorful mobile to their foot and tracking movements with a Vicon 3D motion capture system. The study tested AI's ability to detect changes in infant movement patterns. Findings showed that AI techniques, especially the deep learning model 2D-CapsNet, effectively classified different stages of behavior. Notably, foot movements varied significantly. Looking at how AI classification accuracy changes for each baby gives researchers... Read more ›

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ScienceDaily
ScienceDaily 2 place · 10/01/2024 11:48 EDT

Pervasiveness of inflammation-inducing foods in American diet

Almost six in 10 Americans have pro-inflammatory diets, increasing the risk of health problems including heart disease and cancer, according to a new study that used a tool designed to examine inflammation in the diet. The study also found that certain populations -- including Black Americans, men and people with lower incomes -- were more likely to eat a diet high in pro-inflammatory foods. Read more ›

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ScienceDaily
ScienceDaily · 10/01/2024 11:47 EDT

Carbon dioxide and hydrogen peroxide on Pluto's moon Charon

Astronomers have detected carbon dioxide and hydrogen peroxide on the frozen surface of Pluto's largest moon, Charon, using observations from the James Webb Space Telescope. These discoveries add to Charon's known chemical inventory, previously identified by ground- and space-based observations, that includes water ice, ammonia-bearing species and the organic materials responsible for Charon's gray and red coloration. Read more ›

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ScienceDaily
ScienceDaily · 10/01/2024 11:47 EDT

Squid-inspired fabric for temperature-controlled clothing

Inspired by the dynamic color-changing properties of squid skin, researchers have developed a method to manufacture a heat-adjusting material that is breathable and washable and can be integrated into flexible fabric. The composite material operates in the infrared spectrum and consists of a polymer covered with copper islands. Stretching the material separates the islands and changes how it transmits and reflects infrared light; this innovation creates the possibility of controlling... Read more ›

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ScienceDaily
ScienceDaily · 10/01/2024 11:47 EDT

More clarity on hereditary colorectal cancer

The genetic confirmation of a suspected diagnosis of 'hereditary colorectal cancer' is of great importance for the medical care of affected families. However, many of the variants identified in the known genes cannot yet be reliably classified in terms of their causal role in tumor formation. Scientists have reassessed the medical relevance of a significant number of unclear variants and thus significantly reduced their number. Read more ›

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ScienceDaily
ScienceDaily · 10/01/2024 11:47 EDT

Adapted -- study shows that wild animals also get accustomed to humans

Wild animals are less susceptible to human disturbance if they live in areas with a high human footprint. Researchers have highlighted this in their analysis of large-scale tracking data of more than 1,500 wild animals for an international research project. Individuals that are fitted with measuring devices such as GPS collars recover more quickly from the tagging event if they encounter humans or human tracks more frequently in their habitat.... Read more ›

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ScienceDaily
ScienceDaily · 09/30/2024 21:29 EDT

Traveling population wave in Canada lynx

A new study provides compelling evidence that Canada lynx populations in Interior Alaska experience a 'traveling population wave' affecting their reproduction, movement and survival. This discovery could help wildlife managers make better-informed decisions when managing one of the boreal forest's keystone predators. Read more ›

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ScienceDaily
ScienceDaily · 09/30/2024 21:29 EDT

Where flood policy helps most -- and where it could do more

A Federal Emergency Management Agency (FEMA) program provides important flood insurance relief, researchers say. But due to its design, it's used more in communities with greater means to protect themselves, while lower-resourced areas benefit less. Read more ›

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ScienceDaily
ScienceDaily · 09/30/2024 21:28 EDT

One in three Americans has a dysfunctional metabolism, but intermittent fasting could help

Metabolic syndrome increases many Americans' risk of heart disease, stroke, and type 2 diabetes. A new clinical trial finds that 3 months of time-restricted eating improved patients' blood sugar regulation and metabolic function, which could help ward off serious and chronic diseases. Read more ›

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ScienceDaily
ScienceDaily · 09/30/2024 21:28 EDT

Tongan volcanic eruption triggered by explosion as big as 'five underground nuclear bombs'

The Hunga Tonga underwater volcano was one of the largest volcanic eruptions in history, and now, two years later, new research has revealed its main trigger. Read more ›

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ScienceDaily
ScienceDaily · 09/30/2024 21:28 EDT

Coral reef destruction a threat to human rights

A human rights-based approach to coral reef protection could ensure governments are held to account for safeguarding marine ecosystems. Read more ›

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ScienceDaily
ScienceDaily · 09/30/2024 21:28 EDT

Radon, even at levels below EPA guideline for mitigation, is linked to childhood leukemia

A study of more than 700 counties across multiple U.S. states found a link between childhood leukemia and levels of decaying radon gas, including those lower than the federal guideline for mitigation. Read more ›

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26.11.2024 06:53
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