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976 A protein at the heart of heart disease

ScienceDaily
ScienceDaily · 02/03/2025 14:18 EDT

A protein at the heart of heart disease

Low-density lipoproteins (LDL) -- commonly known as bad cholesterol -- have long been on scientists' radar as a major contributor to heart disease. But these microscopic troublemakers have hidden their inner workings behind a maze of complexity. That is, until now. Researchers have now revealed the specific shape and structure of one of the body's most important yet complicated proteins: ApoB100. Acting as a kind of molecular exoskeleton, this protein wraps around LDL particles, allowing them to travel thro

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