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Depression continues to grapple a large proportion of the population. Given the side effects associated with the long-term use of conventional antidepressants, there is a need for novel rapid acting therapeutics with minimal side effects. Researchers have previously demonstrated antidepressant-like effects of delta opioid receptor agonists in rodents. In their latest study, they uncover the molecular and cellular mechanism underlying its action that can advance its therapeutic development.
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ScienceDaily
An East Bay apartment complex has been bought at a price that's well below its prior value. Read more ›
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A PG&E Corp. unit has bought a San Jose building in a move to bolster the utility's South Bay operations. Read more ›
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Undertaking a second stake sale within a week, Pine Labs’ early backer Actis has now sold 2.39 Cr shares in… Read more ›
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Ukraine says its strike campaigns have prompted Russia to bring out additional defenses. It's not the first time it's tried smoke. Read more ›
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If League of Legends and Valorant players have the right hardware and elect to opt into "pre-boot security mechanisms and Windows' own native protection features," then, starting today, they can switch the Vanguard anti-cheat software from always-on to one that's "on demand." With "Vanguard Pre-Check," the kernel-level driver won't launch when your system does, according […] Read more ›
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The latest Cartoon Network Studios series to hit HBO Max comes after the success of 'Adventure Time: Fionna and Cake' and 'Adventure Time: Distant Lands.' Read more ›
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A peer-reviewed Nature critique argues that Microsoft's 2025 Majorana quantum-computing breakthrough -- and its claim that it could enable "a truly meaningful quantum computer not in decades, as some have predicted, but in years" -- is fundamentally flawed. According to Dr Henry Legg, a lecturer at the University of St Andrews, the claims were undermined by omitted data, selective plotting, and basic Python errors that concealed alternative results. Microsoft, for... Read more ›
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What on Earth is Chuck Lorre up to this time? Stuart Fails to Save the Universe is the Big Bang Theory spinoff nobody expected — here's its release date, trailer, cast and more. Read more ›
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This is day 2 of 4 of Amazon’s annual Prime Day shopping event. Yesterday we looked at the best smartphone deals. Here we will focus on tablets, smartwatches, headphones and other interesting gadgets. Table of Contents: iPads Tablets Amazon tablets Apple Watches Wear OS watches Headphones microSD Apple iPads Amazon is clearing out its inventory of 2024 iPads, specifically the M4-powered iPad Pro 13 and the iPad mini. The mini... Read more ›
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Since the start of the year, cities, towns, counties and states across America have slammed the brakes on allowing new data centers in their backyards. By exhaustively combing through a combination of legal documents and local news reports, The Information has identified more than 300 temporary and permanent bans on data center development that state and local governments throughout the U.S. have passed since 2023, and over 75 more under... Read more ›
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Digital GTA 6 pre-orders come with a free month of GTA+, here's everything you need to know. Read more ›
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Here are the Amazon Prime Day deals you need to kickstart your first Dungeons and Dragons adventure. Read more ›
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How to watch World Cup 2026 in Portugal for free – from anywhere with our football streaming trick. Read more ›
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UK-based staff at the Wikimedia Foundation (WMF), the nonprofit that supports Wikipedia, are pushing forward with their unionization drive. On Wednesday, the staff sent a letter to WMF management requesting the organization voluntarily recognize the union. "The WMF has undergone a period of significant change in recent months, escalating workers' concerns over transparency, trust, and […] Read more ›
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Taylor Swift's soundtrack single for "Toy Story 5" has joined the ranks of No. 1 hits like "Blank Space," "Anti-Hero," and "The Fate of Ophelia." Read more ›
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Amazon's biggest rivals are offering some very, very competitive deals on laptops of all types today. Read more ›
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Cracking your garage door open on a hot day seems like a simple fix to beat the heat, but does it actually work as well as the internet says it does? Read more ›
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Samsung’s S Pen-equipped Galaxy Tab S10 FE is down to $334.99, beating its previous 2026 low by some distance. Read more ›
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ScienceDaily
A major study of more than 112,000 people found that eating foods containing common preservatives may be linked to a higher risk of high blood pressure and heart-related diseases. Researchers tracked participants for up to eight years and discovered that people consuming the highest amounts of certain preservatives had significantly greater risks of hypertension, heart attack, stroke, and other cardiovascular problems. Read more ›
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A major study of Australian native bees found that stem-nesting species may be the first to feel the impact of climate change. Unlike bees that nest underground, they have few ways to escape dangerous heat. Researchers also discovered that tropical bees are particularly vulnerable, even when they are already adapted to hot environments. The findings suggest bee behavior could be a key factor in determining which species survive a warming... Read more ›
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A new study from Northern Arizona University is raising red flags about a widely used global emissions database from Climate TRACE, a consortium co-founded by Al Gore. Researchers found that the database may be dramatically undercounting carbon dioxide emissions from cars and trucks in cities—by an average of 70% across 260 U.S. cities, with some cities showing gaps of more than 90%. Read more ›
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A new theory suggests the universe is constantly recording its own history in the fabric of spacetime. If correct, this cosmic memory could help solve some of the biggest puzzles in physics, from black holes to dark matter and the universe’s ultimate fate. Read more ›
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Plague was already a deadly killer 5,500 years ago, long before cities, farming, or the rat-infested conditions usually linked to historic outbreaks. By analyzing ancient DNA from hunter-gatherer cemeteries in Siberia, researchers discovered early plague strains in nearly 40% of the individuals studied and found evidence of rapid family-based outbreaks that wiped out many children and young teenagers. Read more ›
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A historic lack of snow in the Gila River watershed has left Arizona’s San Carlos Reservoir less than 1% full, triggering a massive fish kill and an indefinite closure. Despite the bleak conditions, heavy summer rains could help the reservoir rebound. Read more ›
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A new study suggests Southern California's major fault system is more stressed than at any point in the last 1,000 years. Researchers found that the Cajon Pass, where the San Andreas and San Jacinto faults meet, could act as an “earthquake gate” that determines whether a future rupture spreads across both faults. Current conditions resemble those that preceded some of the region’s largest historical earthquakes. Read more ›
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Scientists may have uncovered a hidden trigger behind Alzheimer’s disease. Instead of plaques being the root cause, amyloid beta appears to interfere with tau, a protein that helps keep neurons functioning properly. This disruption could set off the damage that eventually leads to the disease’s most recognizable brain changes. Read more ›
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The race to build data centers in space is gaining momentum as AI drives unprecedented demand for computing power. Orbital facilities could tap into abundant solar energy and avoid many of the environmental challenges faced on Earth. Yet space remains a harsh and expensive place to operate, with major hurdles including cooling, maintenance, radiation exposure, and orbital debris. Read more ›
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Astronomers may be closing in on a long-standing cosmic mystery: why some of the universe’s biggest galaxies seem to have far fewer stars than expected. Using NASA- and JAXA-supported XRISM observations of a galaxy called NGC 4151, researchers found strong evidence that supermassive black holes can unleash powerful winds that blow away the raw material needed to make new stars. Read more ›
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24.06.2026 13:14
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