601 place 0

634 New take on immunotherapy reinvigorates T cells by blocking uptake of energy-sapping cancer byproducts

ScienceDaily
ScienceDaily · 11/08/2024 11:35 EDT

New take on immunotherapy reinvigorates T cells by blocking uptake of energy-sapping cancer byproducts

Blocking a protein that imports lactic acid, a metabolic byproduct of cancer cells, reinvigorated exhausted T cells and led to improved tumor control in mouse models of cancer, according to a new study that describes how shutting off T cell access to inhibitory metabolites could be a promising new approach to cancer immunotherapy.

To see detailed statistics for the news please log in »

Read the original

Add your comment
You must be logged in with Facebook to read and write comments.

A newsletter a day!

You may get 10 most important news around midday in daily newsletter. Press the button and we will send you the most important news only, no spam attached.

or register

LIKE us on Facebook so you won't miss the most important news of the day!

News from the same source
ScienceDaily ScienceDaily
Business Insider
Eve Crosbie @ Business Insider 1 place · today 08:36 EDT

Chuck Woolery, original host of 'Wheel of Fortune,' dead at 83

The legendary game show star was best known for hosting "Wheel of Fortune" and "Love Connection." Read more

1,078 fresh

🔮
24.11.2024 ♋︎ Today will be quite a busy day for Cancers. You should be cautious in your... Read more ›
Business Insider
Benjamin Zhang @ Business Insider 2 place · today 05:57 EDT

I drove a $27,000 Chevrolet Trax SUV. It's affordable daily transportation done right

I drove a 2025 Chevrolet Trax 2RS and was impressed by its strong feature content, attractive styling, and affordable price tag. Read more

570 fresh

Wired
Joseph Howlett @ Wired 1 place · today 07:00 EDT

Mathematicians Just Debunked the ‘Bunkbed Conjecture’

This famous probability theory was intuitive, even obvious. It was also wrong. Read more

516 fresh

Business Insider
Tom Carter @ Business Insider 3 place · today 05:02 EDT

Chinese EV makers are not doing quite as well as you might think

Nio, Xiaomi, and Xpeng have all broken sales records in recent months, but continue to report heavy losses. Read more

497 fresh

Wired
Scott Gilbertson @ Wired 2 place · today 09:00 EDT

Lomography Lomo'Instant Wide Glass Review: The Best Instax Camera

A real glass lens in Lomography's new instant camera elevates Instax print to new heights. Read more

415 fresh

Business Insider
Swami Sivasubramanian @ Business Insider · today 05:37 EDT

AI can be used to create job promotion, not be a job replacement, says AWS vice president

Swami Sivasubramanian, AWS Vice President of AI and Data, says that AI can be used as a tool for job promotion, not be a job replacement. Read more

366 fresh

MacRumors
Joe Rossignol @ MacRumors 1 place · today 08:29 EDT

iOS 19 Rumors: More ChatGPT-Like Siri, Some New Features 'Postponed'

iOS 19 is not expected to be announced until June 2025, but the software update's first major new feature has already leaked. In his Power On newsletter today, Bloomberg's Mark Gurman reiterated his previous report that said iOS 19 will introduce a "more conversational Siri" powered by "more advanced large language models." He said this upgrade will make Siri more like OpenAI's ChatGPT, allowing the assistant to "handle more sophisticated... Read more

360 fresh

Slashdot
EditorDavid @ Slashdot 1 place · today 07:34 EDT

Mars Meteorite Reveals New Evidence That Hot Water Flowed on Ancient Mars

"Scientists have found what seems to be the oldest direct evidence of hot water flowing on Mars during its ancient past," reports Space.com. "The discovery could further indicate that the Red Planet, despite its arid and desolate appearance today, may have been capable of supporting life long ago." The evidence was delivered to Earth and sealed within the well-known Martian meteorite NWA7034, found in the Sahara Desert in 2011. Due... Read more

351 fresh

Business Insider
Rebecca Rommen @ Business Insider · today 06:55 EDT

Airlines fume after Spain hits low-cost carriers with $187 million in fines

The fines, which affect Ryanair, Vueling, easyJet, Norwegian, and Volotea, total 179 million euros (around $187 million). Read more

300 fresh

Eurogamer.net
Vikki Blake @ Eurogamer.net 1 place · today 08:09 EDT

Stalker 2's first patch is coming next week - here's what it will include

Developer GSC Game World said Stalker 2: Heart of Chornobyl's first patch will respond directly to feedback from players. Read more Read more

299 fresh

Vox
Dylan Matthews @ Vox 1 place · today 07:00 EDT

Why Elon Musk can never balance the budget, in one chart

Two. Trillion. Dollars. That’s how much Elon Musk, co-chair of President-elect Donald Trump’s new “Department of Government Efficiency,” or DOGE, has said he can cut out of the annual federal budget. Musk and his partner Vivek Ramaswamy have suggested that they can achieve this through “mass head-count reductions across the federal bureaucracy,” by cracking down […] Read more

285 fresh

Business Insider
Katie Balevic,Lauren Edmonds @ Business Insider · today 05:42 EDT

All the many ways brothers Travis and Jason Kelce are expanding their brand

Jason Kelce and Travis Kelce have been busy growing their brands, on-field and off. Here's a look at what they've been up to. Read more

241 fresh

The Verge
David Pierce @ The Verge 1 place · today 08:00 EDT

Two new tech documentaries you really need to see

Image: David Pierce / The Verge Hi, friends! Welcome to Installer No. 61, your guide to the best and Verge-iest stuff in the world. (If you’re new here, welcome, happy Hallmark season, and also you can read all the old editions at the Installer homepage.) I missed you all last week — thanks to everyone who told me you missed Installer, too! Warms my heart, and also makes me feel... Read more

241 fresh

CNET
Liz Kocan @ CNET 1 place · today 08:00 EDT

What's on Streaming This Week? Watch 'Nutcrackers,' 'Our Little Secret' and More

Don't miss the latest on Netflix, Hulu and more. Here's what's coming the week of Nov. 25 to Dec. 1. Read more

238 fresh

Ars Technica
Michael Connors and Peter Halligan, The Conversation @ Ars Technica 1 place · today 07:10 EDT

What delusions can tell us about the cognitive nature of belief

Delusions can sometimes turn into strongly held beliefs. Read more

235 fresh

Business Insider
Jason Guerrasio @ Business Insider · today 06:18 EDT

Inside Kevin Smith's most personal venture yet: Owning his childhood movie theater

Kevin Smith turned the movie theater he grew up going to into a shrine to his filmography. It's also the setting of his latest movie, "The 4:30 movie." Read more

232 fresh

Business Insider
Steven John @ Business Insider · today 07:34 EDT

I tried club sandwiches from Subway, Jimmy John's, and Jersey Mike's, and there's one I wouldn't order again

I ordered a club sandwich from subway, Jimmy John's, and Jersey Mike's to see which popular chain does the classic sub justice. Two stood out. Read more

205 fresh

Business Insider
Jennifer Sor @ Business Insider · today 08:30 EDT

Economists say Trump's immigration plans could deepen US demographic challenges

America's population could plunge as much as 32% if the US were to completely close its borders, one Brookings projection found. Read more

189 fresh

The most popular news from the same source for the last week
ScienceDaily ScienceDaily
ScienceDaily
ScienceDaily 1 place · 11/22/2024 13:03 EDT

In Patagonia, more snow could protect glaciers from melt -- but only if we curb greenhouse gas emissions soon

In an era of dwindling glaciers, Southern Patagonia has managed to hold on to a surprising amount of its ice. But, a new study suggests that this protective effect might be pushed up against its limits soon. Read more

98

ScienceDaily
ScienceDaily 1 place · 11/19/2024 13:25 EDT

Developing an antibody to combat age-related muscle atrophy

As we age, our muscles atrophy. Earlier this year, researchers found that hepatocyte growth factor (HGF), a protein critical in skeletal muscle development loses its functionality due to nitration as we age. Now, the same team has developed a monoclonal antibody that blocks the nitration sites of HGF, effectively preventing the protein's age induced loss of function. Their findings were validated utilizing rat muscles cell culture. Read more

87

ScienceDaily
ScienceDaily 1 place · 11/20/2024 12:19 EDT

Automated 3D computer vision model offers a new tool to measure and understand dairy cow behavior and welfare

Dairy cows typically rest for 10 or more hours a day, so a dry, clean, and comfortable place -- such as a freestall -- to lie down and rest is essential for their health, well-being, and production performance. One key factor in whether stalls are comfortable for cows is the ease with which they can get up and down, so it is common on farms for staff to watch for... Read more

79

ScienceDaily
ScienceDaily 2 place · 11/20/2024 12:23 EDT

Seeing memories form

Resembling a seahorse, as its name implies from the Greek words 'hippos' (horse) and 'kampus' (sea monster), the hippocampus is a brain region crucial for memory formation. But until recently, scientists have not been able to link memory formation to distinct molecular signals. Now, a team of scientists likely opened this black box. Read more

66

ScienceDaily
ScienceDaily · 11/20/2024 19:31 EDT

Weight-loss drug reduces risk of early death for patients with heart failure, trial finds

Weight-loss and diabetes drug tirzepatide can reduce the risk of death or worsening heart failure for patients with obesity and heart failure with preserved pump function, new research reveals. Read more

62

ScienceDaily
ScienceDaily 1 place · 11/22/2024 16:07 EDT

Early Mesoamericans trapped fish far earlier than previously thought

Archaeologists have collected data which indicates the presence of a large-scale pre-Columbian fish-trapping facility. Discovered in the Crooked Tree Wildlife Sanctuary (CTWS), the largest inland wetland in Belize, the team dated the construction of these fisheries to the Late Archaic period (cal. 2000-1900 BCE), pre-dating Amazonian examples by a thousand years or more. Read more

58

ScienceDaily
ScienceDaily 1 place · 11/19/2024 18:16 EDT

HIV latency reversing properties in African plant

The Wistar Institute and the University of Buea in Cameroon has uncovered the mechanisms for a medicinal plant with anti-HIV potential in Croton oligandrus Pierre & Hutch, a species of African tree that has been used in traditional healing in Cameroon to treat a variety of diseases and conditions including cancers and diabetes. Read more

51

ScienceDaily
ScienceDaily 2 place · 11/19/2024 18:16 EDT

Changing the definition of cerebral palsy

Defining cerebral palsy only as a childhood condition fails to acknowledge the many adults living with the disease. Read more

48

ScienceDaily
ScienceDaily 1 place · 11/18/2024 12:57 EDT

When hepatitis E viruses attack nerve cells

Hepatitis E viruses (HEV) typically cause liver infections. They can, however, also infect other organs and cause neurological disorders. Little is yet known about how this process works. A research team has now developed a cell model to study the interaction of the virus with nerve cells. Using this model, the researchers proved that the virus can infect the cells directly and that the cells can't protect themselves against it... Read more

43

ScienceDaily
ScienceDaily 1 place · 11/20/2024 12:26 EDT

Research on gravity in line with Einstein's theory of general relativity

Researchers used the Dark Energy Spectroscopic Instrument to map how nearly 6 million galaxies cluster across 11 billion years of cosmic history. Their observations line up with what Einstein's theory of general relativity predicts. Read more

37

Most popular sources

  • You see 375 news out of 375.
  • Sources 63 out of 63.
Business Insider 37% 10
Mashable 11% 10
Gizmodo 8% 2
CNET 8% 5
Tom's Hardware 6% 1
View sources »

LIKE us on Facebook so you won't miss the most important news of the day!

24.11.2024 10:22
Last update: 10:15 EDT.
News rating updated: 17:11.

What is Times42?

Times42 brings you the most popular news from tech news portals in real-time chart.
Read about us in FAQ section.


Times42 © 2024