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Scientists investigated how an inherited genetic variation common among East Asians contributes to drug resistance in cancer cells, driving more aggressive cancer growth. The team trialled a precision therapy for this group by blocking the action of a protein called MCL-1, successfully killing many of the cancer cells in laboratory studies.
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This surprisingly deep instrument is probably too complicated for its own good. Read more ›
2,605 fresh
America's population could plunge as much as 32% if the US were to completely close its borders, one Brookings projection found. Read more ›
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The legendary game show star was best known for hosting "Wheel of Fortune" and "Love Connection." Read more ›
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Apple released the AirTag in April 2021, so it is now three over and a half years old. While the AirTag has not received any hardware updates since then, a new version of the item tracking accessory is rumored to be in development. Below, we recap rumors about a second-generation AirTag. Timing Apple is aiming to release a new AirTag in mid-2025, according to Bloomberg's Mark Gurman. From his Power... Read more ›
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Black Friday 2024 is just a few days away, and you can already find the year's best prices on nearly every Mac at Amazon. Specifically, this includes the new M4 iMac, M4 MacBook Pro, and the M2 and M3 MacBook Air. We've also included a great deal on the Apple Studio Display. Note: MacRumors is an affiliate partner with Amazon. When you click a link and make a purchase, we... Read more ›
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Developer GSC Game World said Stalker 2: Heart of Chornobyl's first patch will respond directly to feedback from players. Read more Read more ›
528 fresh
Introducing mod support for Baldur's Gate 3 has proved so successful, developer Larian Studios is restricting the number of mods console players can run at any one time. Read more Read more ›
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Nio, Xiaomi, and Xpeng have all broken sales records in recent months, but continue to report heavy losses. Read more ›
466 fresh
I drove a 2025 Chevrolet Trax 2RS and was impressed by its strong feature content, attractive styling, and affordable price tag. Read more ›
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The iQOO 13, introduced in China in October, will begin its international rollout soon, with the India debut set for December 3. The iQOO 13 is powered by the Snapdragon 8 Elite flagship chip and sports a trio of 50MP cameras on the rear. The iQOO 13's 50MP primary camera uses the Sony IMX921 sensor with an f/1.88 aperture. It has OIS and EIS and can record 1080p and 4K... Read more ›
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It may sound like a misnomer, but welcome to Black Friday week – here are the best smartphone, tablet and laptop deals, plus some smart wearables. The Samsung Galaxy S24 Ultra is under $1,000 if you get the 256GB variant. The 512GB model is a $120 upgrade. Samsung Galaxy S24 Ultra $350 off Read our review 12/256GB - $950 at Amazon US 12/512GB - $1,070 at Amazon US... Read more ›
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A real glass lens in Lomography's new instant camera elevates Instax print to new heights. Read more ›
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It's hard to beat the promise of a big box for one-stop shopping. Target is one of my favorites if I just want to browse with no agenda, because I'll inevitably stumble on something fun or on sale. Or in the case of this Black Friday deal, both. Target is currently selling a Meta Quest 3S for $300, as is Amazon. That's the usual price tag for this virtual reality... Read more ›
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With the GOP regaining control of Congress, Republicans are looking to slash health care spending, specifically eyeing Medicaid cuts and work requirements. While those fights are almost certainly going to garner a lot of coverage, it’s important to also pay attention to some of the less splashy policies also on the chopping block. These might […] Read more ›
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Swami Sivasubramanian, AWS Vice President of AI and Data, says that AI can be used as a tool for job promotion, not be a job replacement. Read more ›
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Image: David Pierce / The Verge Hi, friends! Welcome to Installer No. 61, your guide to the best and Verge-iest stuff in the world. (If you’re new here, welcome, happy Hallmark season, and also you can read all the old editions at the Installer homepage.) I missed you all last week — thanks to everyone who told me you missed Installer, too! Warms my heart, and also makes me feel... Read more ›
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The shaker hood is a classic element of some of Pontiac's most popular models, but did the design actually help with performance or was it just for marketing? Read more ›
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iOS 19 is not expected to be announced until June 2025, but the software update's first major new feature has already leaked. In his Power On newsletter today, Bloomberg's Mark Gurman reiterated his previous report that said iOS 19 will introduce a "more conversational Siri" powered by "more advanced large language models." He said this upgrade will make Siri more like OpenAI's ChatGPT, allowing the assistant to "handle more sophisticated... Read more ›
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The fines, which affect Ryanair, Vueling, easyJet, Norwegian, and Volotea, total 179 million euros (around $187 million). Read more ›
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The new Asus ROG Phone 9 series brings more processing power, better cooling, a faster display and a bigger battery. That makes them the ultimate gaming phones, right? Maybe, but they are not without their flaws Asus ROG Phone 9 Pro The Asus ROG Phone 9 and 9 Pro will receive only 2 OS updates (they start with Android 15) and will continue getting security patches for 5 years. The... Read more ›
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ScienceDaily
In an era of dwindling glaciers, Southern Patagonia has managed to hold on to a surprising amount of its ice. But, a new study suggests that this protective effect might be pushed up against its limits soon. Read more ›
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As we age, our muscles atrophy. Earlier this year, researchers found that hepatocyte growth factor (HGF), a protein critical in skeletal muscle development loses its functionality due to nitration as we age. Now, the same team has developed a monoclonal antibody that blocks the nitration sites of HGF, effectively preventing the protein's age induced loss of function. Their findings were validated utilizing rat muscles cell culture. Read more ›
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Dairy cows typically rest for 10 or more hours a day, so a dry, clean, and comfortable place -- such as a freestall -- to lie down and rest is essential for their health, well-being, and production performance. One key factor in whether stalls are comfortable for cows is the ease with which they can get up and down, so it is common on farms for staff to watch for... Read more ›
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Resembling a seahorse, as its name implies from the Greek words 'hippos' (horse) and 'kampus' (sea monster), the hippocampus is a brain region crucial for memory formation. But until recently, scientists have not been able to link memory formation to distinct molecular signals. Now, a team of scientists likely opened this black box. Read more ›
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Weight-loss and diabetes drug tirzepatide can reduce the risk of death or worsening heart failure for patients with obesity and heart failure with preserved pump function, new research reveals. Read more ›
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Archaeologists have collected data which indicates the presence of a large-scale pre-Columbian fish-trapping facility. Discovered in the Crooked Tree Wildlife Sanctuary (CTWS), the largest inland wetland in Belize, the team dated the construction of these fisheries to the Late Archaic period (cal. 2000-1900 BCE), pre-dating Amazonian examples by a thousand years or more. Read more ›
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The Wistar Institute and the University of Buea in Cameroon has uncovered the mechanisms for a medicinal plant with anti-HIV potential in Croton oligandrus Pierre & Hutch, a species of African tree that has been used in traditional healing in Cameroon to treat a variety of diseases and conditions including cancers and diabetes. Read more ›
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Defining cerebral palsy only as a childhood condition fails to acknowledge the many adults living with the disease. Read more ›
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Hepatitis E viruses (HEV) typically cause liver infections. They can, however, also infect other organs and cause neurological disorders. Little is yet known about how this process works. A research team has now developed a cell model to study the interaction of the virus with nerve cells. Using this model, the researchers proved that the virus can infect the cells directly and that the cells can't protect themselves against it... Read more ›
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Researchers used the Dark Energy Spectroscopic Instrument to map how nearly 6 million galaxies cluster across 11 billion years of cosmic history. Their observations line up with what Einstein's theory of general relativity predicts. Read more ›
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Business Insider
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40% 7 |
Mashable
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11% 10 |
CNET
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8% 5 |
Gizmodo
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6% 0 |
Wired
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5% 3 |
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24.11.2024 10:41
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