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Buildup of a protein called filamentous actin, or F-actin, in the brain inhibits the removal of cellular wastes, including DNA, lipids, proteins and organelles. The resulting accumulation of waste diminishes neuronal functions and contributes to cognitive decline. By tweaking a few very specific genes in the neurons of aging fruit flies, the researchers prevented F-actin buildup, maintained cellular recycling and extended the healthy lifespan of fruit flies by approximately 30%.
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ScienceDaily
If you plan on using an extension cord or power strip to juice up your home this year, try to find an alternate option for these specific items. Read more ›
359 fresh
Sam Wilson may be just a guy, but Brave New World will show why he's the right guy to pick up Steve's mantle. Read more ›
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SpaceX could significantly increase the number of Starship launches in 2025 as it readies the vehicle for crew and cargo trips to the moon and beyond. Read more ›
290 fresh
Over the last several years, Salesforce CEO Marc Benioff said we've all "got drunk on the ChatGPT Kool-Aid" but AI is more expansive than LLMs. Read more ›
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As Comcast readies a sale of its legacy media outlet, the rightwing billionaire has mused about an acquisition. Read more ›
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Dataminers have discovered the ages of Dragon Age: The Veilguard's cast as given by developer BioWare. Read more Read more ›
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Cosmonauts aboard the Russian segment of the station donned protective equipment. Read more ›
171 fresh
Microsoft says it’s working with Ubisoft to fix a problem with its latest Windows 11 update that’s been crashing some games, and it’s put the update’s release on pause for devices with those games in the meantime. Following users’ reports of issues after installing the Windows 11 24H2 update, Microsoft confirmed this weekend that certain games may become unresponsive or display a black screen. The problem affects Assassin's Creed Valhalla,... Read more ›
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"Wicked," Universal Pictures' highly anticipated film, topped the domestic box office with an estimated $114 million after its Friday premiere. Read more ›
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Here are some hints — and the answers — for Connections: Sports Edition No. 63 for Nov. 25. Read more ›
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The new legislation likely aims to boost recruitment amid soaring Russian combat losses. Read more ›
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Tim Cook and then-President Donald Trump, speaking to the Press in Austin, Texas in 2019. | Photo: Mandel Ngan / AFP via Getty Images Apple CEO Tim Cook managed to forge a personal relationship with Donald Trump during his first Presidential term that other tech firms struggled to replicate. Now, others are trying to follow his template, says a Wall Street Journal report today. Cook used direct appeals to influence... Read more ›
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Bluesky has quickly become a popular social media app as users attempt to flee the site formerly known as Twitter. Here's how Bluesky differs from X. Read more ›
128 fresh
Give away the gift of a lifetime's worth of conversation-starting documentaries for a staggering 60% off this Black Friday. Read more ›
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America's population could plunge as much as 32% if the US were to completely close its borders, one Brookings projection found. Read more ›
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I've home-tested the Shelfy Smart Refrigerator device. It claims to keep your produce fresher for longer, but I loved its smart app features. Read more ›
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Elon Musk threatened to purchase MSNBC. Joe Rogan had ideas, too. Of course he did. Read more ›
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ScienceDaily
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As we age, our muscles atrophy. Earlier this year, researchers found that hepatocyte growth factor (HGF), a protein critical in skeletal muscle development loses its functionality due to nitration as we age. Now, the same team has developed a monoclonal antibody that blocks the nitration sites of HGF, effectively preventing the protein's age induced loss of function. Their findings were validated utilizing rat muscles cell culture. Read more ›
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Dairy cows typically rest for 10 or more hours a day, so a dry, clean, and comfortable place -- such as a freestall -- to lie down and rest is essential for their health, well-being, and production performance. One key factor in whether stalls are comfortable for cows is the ease with which they can get up and down, so it is common on farms for staff to watch for... Read more ›
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Resembling a seahorse, as its name implies from the Greek words 'hippos' (horse) and 'kampus' (sea monster), the hippocampus is a brain region crucial for memory formation. But until recently, scientists have not been able to link memory formation to distinct molecular signals. Now, a team of scientists likely opened this black box. Read more ›
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Weight-loss and diabetes drug tirzepatide can reduce the risk of death or worsening heart failure for patients with obesity and heart failure with preserved pump function, new research reveals. Read more ›
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Archaeologists have collected data which indicates the presence of a large-scale pre-Columbian fish-trapping facility. Discovered in the Crooked Tree Wildlife Sanctuary (CTWS), the largest inland wetland in Belize, the team dated the construction of these fisheries to the Late Archaic period (cal. 2000-1900 BCE), pre-dating Amazonian examples by a thousand years or more. Read more ›
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The Wistar Institute and the University of Buea in Cameroon has uncovered the mechanisms for a medicinal plant with anti-HIV potential in Croton oligandrus Pierre & Hutch, a species of African tree that has been used in traditional healing in Cameroon to treat a variety of diseases and conditions including cancers and diabetes. Read more ›
51
Defining cerebral palsy only as a childhood condition fails to acknowledge the many adults living with the disease. Read more ›
48
Hepatitis E viruses (HEV) typically cause liver infections. They can, however, also infect other organs and cause neurological disorders. Little is yet known about how this process works. A research team has now developed a cell model to study the interaction of the virus with nerve cells. Using this model, the researchers proved that the virus can infect the cells directly and that the cells can't protect themselves against it... Read more ›
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Researchers used the Dark Energy Spectroscopic Instrument to map how nearly 6 million galaxies cluster across 11 billion years of cosmic history. Their observations line up with what Einstein's theory of general relativity predicts. Read more ›
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Most popular sources
Business Insider
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31% 15 |
CNET
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11% 8 |
Tom's Hardware
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9% 3 |
Gizmodo
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7% 1 |
Eurogamer.net
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6% 5 |
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