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549 Scientists discover hidden liver switch that cuts harmful cholesterol

ScienceDaily
ScienceDaily · 05/24/2026 22:52 EDT

Scientists at UT Southwestern have uncovered a surprising new “master switch” that helps control how much cholesterol the liver sends into the bloodstream. The newly identified protein, HELZ2, works by shutting down the genetic instructions needed to produce apoB — a key building block of the cholesterol-carrying particles linked to clogged arteries and heart disease.

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