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A trio of common amino acids may hold the key to unlocking far more powerful gene therapies. Researchers found that adding them to lipid nanoparticles can boost mRNA delivery up to 20-fold and push CRISPR editing efficiency close to 90%. The trick isn’t changing the drug—but helping cells take it in more easily. In early tests, the approach dramatically improved survival and treatment outcomes, pointing to a simple but game-changing upgrade for future medicine.
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ScienceDaily
An East Bay apartment complex has been bought at a price that's well below its prior value. Read more ›
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A PG&E Corp. unit has bought a San Jose building in a move to bolster the utility's South Bay operations. Read more ›
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If Instagram has been turning your color photo posts into black and white recently, don’t worry, there’s no problem with your camera or your account. The Meta-owned app has confirmed to Engadget that the issue is caused by a bug that’s affecting HDR photos in particular. "Earlier today, a technical issue caused some HDR photos to appear incorrectly as black-and-white for a subset of accounts,” Instagram has told us. However,... Read more ›
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Seeing this idea take shape for smart rings, it’s difficult not to be impressed by how good it actually is. Read more ›
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Привет, Хабр! (И тебе, случайный бухгалтер, который думает, что «выгрузить из банка» - это нажать одну кнопку. И тебе, 1С-разработчик, который слышит «парсинг PDF» и сразу уходит на больничный. И тебе, Python-разработчик, который уверен, что pip install magic_solution решит любую проблему.)Сегодня расскажу, как мне поставили задачу, от которой у SAP-а ушло, видимо, несколько команд и много времени, а мне дали на это… ну, скажем так, поменьше. Задача звучала элегантно, но... Read more ›
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Great for small businesses and quick hires, but hidden fees and uneven support let it down. Read more ›
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Shares of Groww surged as much as 8.55% during the intraday trading today, touching a high of ₹213.25 on the… Read more ›
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Attorney General Rob Bonta said Amazon asked vendors like Levi's to pressure Walmart into raising prices. Read more ›
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Привет, Хабр. Обо мне: я не программист, не DevOps и не 1С-ник. Я работаю в небольшой компании, занимаюсь самыми разными задачами, в том числе небольшими ИТ-внедрениями на уровне «настроить, связать, запустить». Часто слышу про критику ИИ причем в любой сфере. Вот решил немного рассказать о своем опыте использования для решения микро задач.В малом бизнесе постоянно возникает мелкая ИТ-рутина. Тут нужно данные спарсить, там - файл конвертировать, здесь - логику кнопки... Read more ›
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Never paid attention to the box in the corner of the office? Maybe it’s time to start – here are ten amazing facts about your laser printer. Read more ›
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Фасетный поиск в eCommerce — штука коварная. Пока фильтров три и категорий пять — можно написать примерно любое своё решение и оно будет работать. Но когда каталог растёт, появляются десятки фасетов, динамические атрибуты, а пользователи начинают кликать по фильтрам быстрее, чем успевает обновляться интерфейс, — тут-то и начинаются сложности.В этой статье я расскажу, как мы прошли путь от самописного велосипеда через InstantSearch.js с кастомным клиентом до связки TanStack Query +... Read more ›
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В 1981 году IBM PC 5150 поставлялся с 16 или 64 КБ оперативной памяти, а максимальная конфигурация ограничивалась 640 КБ — архитектурным барьером первого поколения процессоров Intel. Сегодня флагманские десктопы и серверы оснащаются 192 ГБ DDR5-памяти. Это рост в 300 000 раз за четыре десятилетия. И памяти все также не хватает.За это время сменилось больше десятка стандартов: 30-контактные SIMM, которые нужно было устанавливать парами, продуваемые EDO-модули, провалившаяся RIMM для Pentium... Read more ›
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A focus on metabolic health — how the body produces, uses, and stores energy — is not merely a trend. Although 80 per cent of all women will be affected by a chronic illness at some point in their liv... Read more ›
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В малом и среднем бизнесе ИТ-аутсорсинг часто начинается не с аудита и архитектуры, а с подписания абонентского договора. В результате подрядчик тонет в заявках, а инфраструктура продолжает работать как попало. При этом владелец бизнеса ждет от «поддержки» и починку вчерашних проблем, и построение завтрашних сервисов в рамках одной фиксированной платы. Через несколько месяцев становится ясно, что количество инцидентов растет, а риски не уменьшаются. Читать далее Read more ›
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Zynt, a Warsaw-based startup building a signal intelligence platform for B2B sales, has closed a €424.4k ($500k) pre-Seed round to advance the technology, prepare the product for enterprise clients, and fuel international expansion. The funding was secured from Poland-based fund 24Ventures and a group of angel investors. “We see Zynt as a response to a ... Read more ›
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Хабр, привет! Меня зовут Вячеслав Демин, я больше пяти лет работаю в сфере Data Science. Сейчас я руководитель направления аналитики данных в Сбере и эксперт на курсе «Специалист по Data Science» в Яндекс Практикуме. Начинал с этого же курса в 2020 году, после чего работал в сфере страхования и нефтехимии.В этом материале я расскажу, для каких задач в Data Science использую ИИ и почему полагаться на него на 100% всё... Read more ›
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Polishstartup Zynt, which develops a signal intelligence platform for B2B sales, hasclosed a $500,000 pre-seed funding round. The company was founded by CezaryRaszel and Wojciech Ozimek and backed by ... Read more ›
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The layer-2 network's security council moved 30,766 ETH to a frozen intermediary wallet, accessible only via further governance action. Read more ›
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ScienceDaily
Loneliness may quietly affect how well older adults remember things—but it might not be speeding up mental decline after all. A large European study tracking over 10,000 people for seven years found that those who felt lonelier started off with weaker memory, yet their memory didn’t deteriorate any faster than those who felt more socially connected. The findings challenge the idea that loneliness directly accelerates cognitive decline or dementia, suggesting... Read more ›
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Scientists have discovered a way to supercharge the immune system’s T cells by blocking a protein called Ant2, forcing the cells to rewire how they generate energy. This shift makes them more powerful, resilient, and effective at finding and destroying cancer cells. Read more ›
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Bread and other carbohydrate staples may be doing more than just filling plates—they could be quietly reshaping metabolism. In a surprising twist, researchers found that mice strongly preferred carbs like bread, rice, and wheat, abandoning their regular diet entirely. Even without eating more calories, they gained weight and body fat, not because they overate, but because their bodies burned less energy. Read more ›
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A new study from the University of Hawaiʻi at Mānoa is overturning a decades-old belief that Indigenous Hawaiians hunted native waterbirds to extinction. Instead, researchers found no scientific evidence supporting this claim and propose a more complex explanation involving climate change, invasive species, and shifts in land use—many occurring before Polynesian arrival or after traditional stewardship systems were disrupted. Read more ›
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A breakthrough experiment has shed new light on one of astrophysics’ biggest mysteries: the origin of rare proton-rich elements. For the first time, scientists directly measured a key reaction that creates selenium-74 using a rare isotope beam. The results sharpen models of how these elements form in supernova explosions, cutting uncertainty in half. But the findings also reveal gaps in current theories, hinting that the story isn’t complete yet. Read more ›
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In the aftermath of Earth’s most catastrophic extinction event, one unlikely survivor rose to dominate a shattered world: Lystrosaurus. Now, a stunning fossil discovery—an ancient egg containing a curled-up embryo—has finally answered a decades-old mystery about whether mammal ancestors laid eggs. Using advanced imaging technology, scientists confirmed that these resilient creatures did reproduce this way, likely producing large, soft-shelled eggs packed with nutrients. Read more ›
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In the Arizona desert, scientists have uncovered a bizarre and almost unbelievable partnership between ants: tiny cone ants acting as “cleaners” for much larger harvester ants. Instead of attacking, the smaller ants crawl over the giants, licking and nibbling their bodies—even venturing between their open jaws—while the larger ants calmly allow it. The scene resembles underwater “cleaning stations,” where small fish groom predators like sharks. Read more ›
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A major new study reveals that treating gout may do far more than ease painful joint flare-ups—it could also protect the heart. Researchers found that patients who took common gout medications like allopurinol and successfully lowered their blood urate levels had a significantly reduced risk of heart attacks, strokes, and cardiovascular death over five years. Read more ›
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A rare fossil discovery is shedding light on the “missing years” of early sponge evolution. Scientists found a 550-million-year-old sponge that likely lacked hard skeletal parts, explaining why earlier fossils are so scarce. This supports the idea that the earliest sponges were soft-bodied and rarely preserved. The finding changes how researchers hunt for the origins of animal life. Read more ›
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Scientists have taken a major step toward stopping Epstein-Barr virus (EBV), an extremely common infection linked to cancer and chronic disease. By using mice engineered with human antibody genes, researchers created powerful human-like antibodies that block the virus from attaching to and entering immune cells. One of these antibodies completely prevented infection in lab models with human immune systems, marking a breakthrough after years of difficulty tackling EBV’s ability to... Read more ›
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21.04.2026 02:36
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