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A trio of common amino acids may hold the key to unlocking far more powerful gene therapies. Researchers found that adding them to lipid nanoparticles can boost mRNA delivery up to 20-fold and push CRISPR editing efficiency close to 90%. The trick isn’t changing the drug—but helping cells take it in more easily. In early tests, the approach dramatically improved survival and treatment outcomes, pointing to a simple but game-changing upgrade for future medicine.
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An East Bay apartment complex has been bought at a price that's well below its prior value. Read more ›
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A PG&E Corp. unit has bought a San Jose building in a move to bolster the utility's South Bay operations. Read more ›
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Cecil Rhodes arrived at the Kimberley diamond diggings as a sickly 18-year-old in 1871 and spent seventeen years buying out every rival. By 1889 his De Beers Consolidated Mines controlled roughly 90 percent of the world's rough diamond production — a monopoly that would shape the price of an engagement ring for the next 130 years. Read more ›
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Frances Gerety scribbled 'A Diamond Is Forever' late one night in 1947 at a Philadelphia ad agency. The four-word line reshaped marriage across 40 countries. She never married. Read more ›
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On May 24, 1844, Samuel Morse sat in the basement of the US Capitol and tapped a four-word verse from the Book of Numbers down 38 miles of copper wire to Baltimore — a message chosen by his friend's 17-year-old daughter, encoded in an alphabet his assistant had built by counting letters in a newspaper typesetter's case. Read more ›
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Это статья о том, как избыток симметрии делает задачу принципиально нерешаемой. Корни уравнения пятой степени невозможно выразить формулой именно потому, что они слишком симметричны. Разберёмся, как симметрия из привычного инструмента упрощения превращается в препятствие. Читать далее Read more ›
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Most major sporting events do not live up to their names — literally, at least. Major League Baseball’s World Series apparently envisions a world that only includes the US and Canada. The National Football League’s Super Bowl is only rarely super, as those of us who watched February’s 29-13 snoozefest between the Seahawks and Patriots […] Read more ›
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The shift from parent-as-role to parent-as-person rarely arrives through the structured conversation everyone keeps trying to have. It arrives sideways, in a sentence so small it barely registers — and that's exactly why it works. Read more ›
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A brand like Samsung produces appliances in just about every product category, and that includes refrigerators, but it doesn't make ones everyone likes. Read more ›
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Many retirees keep waking before dawn even when nothing in their lives requires it. The reason isn't aging or insomnia — it's something quieter, and more deliberate, about who the early hour belongs to. Read more ›
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Cymothoa exigua, the tongue-eating louse, is the only animal known to anatomically replace a host's organ — entering a fish through the gills, severing the tongue's blood supply, and taking its place for the rest of the fish's life. Read more ›
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I take each of my three kids on solo trips and they get to do whatever they want. They have different travel preferences. Read more ›
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The Garmin Epix Pro (Gen 2) is one of the manufacturer's best watches and an excellent option for serious runners — it's now down to a fantastic low price in the US and the UK. Read more ›
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Instacart's Caper Carts bring fast checkout, coupons, and loyalty perks to Weis stores, but their cameras, location tracking, and in-aisle ads make the grocery cart feel like a data machine. Read more ›
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Realtor.com ranked the best and worst states to buy a home, and the Midwest and Southern states came out on top. Read more ›
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Shadowbyt3$ is asking for $2 million in exchange for the data, but Nintendo seemingly turned the offer down. Read more ›
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ACE CPU extensions bring an efficient AI-oriented instruction set to x86 — new design makes matrix multiplication more power- and density-efficient Read more ›
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На днях встретился с бывшими коллегами-налоговиками, которые, как и я, недавно ушли со службы. Обсудили то, что сейчас происходит в ФНС, региональных инспекциях, как в целом себя ощущает бизнес. И по нашему мнению пока на ПМЭФ заявляют, что с налоговой нагрузкой все в порядке и палку никто не перегнул, на самом деле все гораздо менее радужно, а то будущее которое нам готовит, грозит и вовсе «похоронить» малый и средний бизнес.... Read more ›
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The latest test of the anti-establishment wave sweeping the Democratic Party comes this Tuesday in New York. One year after Zohran Mamdani won the Democratic nomination for mayor of New York City and became a partywide icon, the state has turned into a live read on the rift between the party’s left flank and its […] Read more ›
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Hi, friends! Welcome to Installer No. 133, your guide to the best and Verge-iest stuff in the world. (If you're new here, welcome, happy belated Juneteenth, and also you can read all the old editions at the Installer homepage.) This week, I've been reading about Sam Bankman-Fried and PE Guy and admin nights (which we […] Read more ›
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Using the Keck Observatory, astronomers measured the spins of dozens of giant planets and brown dwarfs orbiting distant stars. They found that giant planets can spin faster than much more massive brown dwarfs, challenging simple assumptions about mass and rotation. The results suggest that magnetic fields and formation processes play a major role in determining how fast worlds end up spinning. Read more ›
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A newly identified crocodile species nicknamed “Lucy’s hunter” prowled Ethiopia’s rivers when Lucy’s species walked the Earth more than 3 million years ago. The giant predator was likely the most dangerous animal in the ecosystem and may have regularly hunted early human relatives. Read more ›
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A three-year study of nearly 4,000 adults ranging from age 19 to 94 found that brain health can improve at any age, challenging the common belief that mental sharpness must decline as we get older. Participants spent just a few minutes a day on brain-training activities, and researchers found measurable gains across multiple aspects of brain health, including thinking clarity, emotional well-being, and sense of purpose. Read more ›
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Ancient encounters between humans and the mysterious Denisovans are still shaping people today. By analyzing genomes from populations across the Pacific, researchers uncovered evidence that the ancestors of Near Oceanians interbred with at least three different Denisovan groups, leaving behind genetic variants that remain active in modern humans. Read more ›
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A new international study finds that middle-aged Americans are lonelier, more depressed, and experiencing worse memory and health than earlier generations. Researchers say growing financial strain, weaker social supports, and chronic stress may explain why the U.S. is falling behind other wealthy nations. Read more ›
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One of the most celebrated claims about Yellowstone’s wolves is facing a major challenge. Scientists say the study behind the famous trophic cascade story relied on flawed methods that overstated the ecological impact of wolf recovery. Their reanalysis found no evidence for a dramatic, park-wide surge in willow growth. Instead, the effects appear smaller and vary from place to place. Read more ›
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Parrots may be doing more than just repeating words—they may actually use names. By analyzing hundreds of recordings from pet parrots, researchers found evidence that many birds use specific names to identify particular people, animals, and even individual companions. Some parrots appeared to refer to someone who wasn’t present, while others used names in creative ways, such as saying their own name to grab attention. Read more ›
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People taking popular weight-loss drugs such as Ozempic, Wegovy, Mounjaro, and Zepbound may be losing pounds, but they could also be moving less. Researchers analyzing Fitbit data found that daily step counts and exercise levels dropped after people started these medications, despite successful weight loss. Because the drugs can reduce muscle mass along with fat, the decline in physical activity raises concerns about preserving strength and long-term health. Read more ›
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A surprising new study suggests that completely eliminating sugar may backfire. Mice on a sucrose-free low-fat diet showed worse blood sugar control, increased inflammation, disrupted gut bacteria, and signs of fatty liver compared with mice that consumed some sucrose. Researchers say the results highlight the importance of a balanced diet and a healthy gut microbiome rather than focusing solely on cutting out sugar. Read more ›
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Millipedes may have been crawling across Earth's landscapes nearly 460 million years ago, long before vertebrates ventured onto land. A new study finally completes their evolutionary family tree, revealing surprising clues about these ancient ecosystem engineers and their early chemical defenses. Read more ›
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20.06.2026 08:57
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