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A trio of common amino acids may hold the key to unlocking far more powerful gene therapies. Researchers found that adding them to lipid nanoparticles can boost mRNA delivery up to 20-fold and push CRISPR editing efficiency close to 90%. The trick isn’t changing the drug—but helping cells take it in more easily. In early tests, the approach dramatically improved survival and treatment outcomes, pointing to a simple but game-changing upgrade for future medicine.
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ScienceDaily
An East Bay apartment complex has been bought at a price that's well below its prior value. Read more ›
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A PG&E Corp. unit has bought a San Jose building in a move to bolster the utility's South Bay operations. Read more ›
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Snapchat Planets turns your friendship ranking into a tiny social solar system, where being Mercury is elite and Neptune might sting a little. Read more ›
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Все мы любим envsubst за простоту, но он примитивен. Переходить на Python с Jinja2 ради шаблонизации конфигов в CI/CD — всё равно что стрелять из пушки по воробьям, да и тащить рантайм ради пары переменных не хочется. В мире Go есть неплохие аналоги, но их вес в 100 МБ вгоняет в тоску, когда стремишься к минимализму в Docker-образах.Теперь всё изменилось так как появился muenvsubst — замена стандартной утилите, написанная на... Read more ›
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I sifted through the fine print and figured out how to score the best deal right now on all the major carriers. Read more ›
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Xiaomi unveiled the 17T and 17T Pro earlier this week and both phones are now available for purchase on Amazon UK. Better yet, both smartphones have received launch discounts as well. Meanwhile, deals are also available on select Samsung Galaxy models, Google's Pixel 10 and Pixel 10a, and the Nothing Phone (3). The Xiaomi 17T gets £150 off its price, whereas the Xiaomi 17T Pro gets a £200 discount. Customers... Read more ›
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Google has lost a lot of goodwill and support in the smart home space and has to make up for it. Read more ›
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The median annual pay for retail salespersons is about $34,750 per year. Several top-paid retail CEOs make that much every single day of the year. Read more ›
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Substack sees a future where you can enjoy your favorite TV show as a blog and interact directly with its creators and stars in the comment section. Read more ›
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Я сделал приложение NeonDrift — живые обои для macOS на основе Metal-шейдеров. Для базовой работы не нужны сторонние библиотеки, Screen Recording или Accessibility-доступ. Только AppKit, MetalKit и SwiftUI.В статье разберу как это устроено изнутри: от трюка с уровнями окон до шейдеров и упаковки в .app. Попутно расскажу про баги, которые я поймал в процессе — растянутую плазму на Retina, крэш при первом же запуске упакованного приложения, анимацию, которая сбрасывалась при... Read more ›
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Thick as Thieves feels like it has a story to tell. And not just the one about talking effigies and mysterious diamonds that plays out across its relatively brisk campaign. Rather, the story of its seemingly sudden lurch away from PvP, its truncated launch state, and its somewhat awkwardly papered cracks. But whatever that story may be, and whatever its resulting flaws, this odd little nubbin of a co-operative first-person... Read more ›
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Говорят, Россия вымирает. Я скачал данные World Bank за 65 лет, построил 8 графиков и проверил. Вот что нашёл. Решайте сами. Читать далее Read more ›
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Makris Athens is a Michelin-starred restaurant with views of the Acropolis. The playful, imaginative dishes beautifully showcase Greek ingredients. Read more ›
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Christiane Schroeter studied in the US and stayed for her work instead of returning to Germany. She says California is like a "Goldilocks place." Read more ›
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Представьте ситуацию: вы только что вернулись из (заслуженного) отпуска с друзьями и, конечно, сделали множество фотографий. Вы хотите отправить друзьям фото с ними. Но как сделать это эффективно? Можно просмотреть фотографии вручную и отметить каждого друга отдельно. Но вы только вернулись из отпуска, ваш электронный почтовый ящик переполнен, и на просмотр фото совсем нет времени. Как же быть? Читать далее Read more ›
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Mayor Zohran Mamdani pitched new builds, rezoning, and more affordable housing for NYC. Other cities in the US and Europe have already tried it. Read more ›
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Older business-class cabins make flying with a baby far easier for my family of three in a way that newer suite-style pods can't. Here's why. Read more ›
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![[Перевод] Квантовые компьютеры не угроза 128-битным симметричным ключам](https://times42.com/media/9/3/3/12509933_640x200.jpg "[Перевод] Квантовые компьютеры не угроза 128-битным симметричным ключам")
Надвигающаяся угроза со стороны заточенных на криптографию квантовых компьютеров заставила срочно менять действующие примитивы асимметричной криптографии — обмен ключами (ECDH) и цифровые подписи (RSA, ECDSA, EdDSA) — которые уязвимы для квантового алгоритма Шора. Однако существующих симметричных методов криптографии (AES, SHA-2, SHA-3) или уровней их стойкости это не коснулось. cccВ индустрии бытует заблуждение, что квантовые компьютеры вдвое ослабят безопасность симметричных ключей, и для обеспечения того Read more ›
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College graduates know about AI. Speakers, including former Google CEO Eric Schmidt, have learned to tread carefully when discussing it commencement. Read more ›
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Losing weight may involve rewiring the gut and the brain at the same time. In a study of obese adults, an intermittent fasting-style diet led to significant weight loss, healthier metabolic markers, and notable shifts in gut bacteria. Brain scans also revealed changes in regions tied to appetite, cravings, and self-control. The results suggest the gut microbiome and brain may work together to influence weight-loss success. Read more ›
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ScienceDaily
Scientists have directly watched angular momentum move through a crystal for the very first time — and discovered a bizarre twist along the way. Using ultra-powerful terahertz laser pulses, researchers triggered tiny atomic rotations inside a quantum material and found that the direction of rotation can unexpectedly flip as momentum is transferred. The strange reversal happens because of the crystal’s underlying symmetry, creating an almost impossible-sounding effect where two rotations... Read more ›
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A mysterious particle from deep space has scientists buzzing after the most energetic neutrino ever detected slammed through the Mediterranean Sea. Now, researchers think they may have identified the cosmic “culprits” behind it: blazars — supermassive black holes blasting jets of matter straight toward Earth. Read more ›
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By analyzing over 400,000 Reddit posts, researchers discovered that users of popular GLP-1 weight-loss drugs frequently discussed unexpected symptoms like menstrual irregularities, chills, and hot flashes. The findings suggest AI could turn social media into a powerful early-warning system for spotting side effects that clinical trials may miss. Read more ›
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For millions battling chronic nerve pain, even the softest touch can feel agonizing — but scientists may have uncovered a radically new way to stop it at the source. Researchers at Duke University found that damaged nerves can be revived by supplying them with healthy mitochondria, the tiny energy producers inside cells. Read more ›
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Scientists have uncovered the oldest known hand-held wooden tools ever used by humans — and they’re an astonishing 430,000 years old. Buried for hundreds of thousands of years at an ancient lakeside site in Greece, the carefully carved wooden objects reveal that early humans were far more skilled and resourceful than once believed. Read more ›
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Scientists have cracked open the “black box” of feline cancer in a landmark study that genetically analyzed nearly 500 cat tumors from around the world. The research uncovered striking similarities between cancers in cats, dogs, and humans — including shared cancer-driving genes tied to aggressive breast cancers. Read more ›
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Researchers found that adding bananas to berry smoothies can dramatically reduce the body’s ability to absorb healthy flavanols. The surprising discovery shows that even simple food combinations can change how much nutrition your body actually gets. Read more ›
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Scientists at UT Southwestern have uncovered a surprising new “master switch” that helps control how much cholesterol the liver sends into the bloodstream. The newly identified protein, HELZ2, works by shutting down the genetic instructions needed to produce apoB — a key building block of the cholesterol-carrying particles linked to clogged arteries and heart disease. Read more ›
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Scientists at McGill University have found a way to supercharge the immune system’s natural killer (NK) cells, helping them break through the defenses tumors use to stay alive. By temporarily blocking two proteins, researchers turned these cells into far more effective cancer fighters against difficult cancers like leukemia, glioblastoma, kidney cancer, and triple-negative breast cancer. Read more ›
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Drinking nitrate-rich beetroot juice may do more than support heart health — it could actually reshape the bacteria living in the mouth in ways that help lower blood pressure in older adults. In the largest study of its kind, researchers found that older people who drank concentrated beetroot juice twice daily for two weeks experienced noticeable blood pressure reductions, while younger adults did not. Read more ›
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31.05.2026 05:59
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