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865 Common IBS medications linked to higher risk of death in major study

ScienceDaily
ScienceDaily · 04/16/2026 05:19 EDT

A massive, nearly 20-year study tracking over 650,000 Americans with irritable bowel syndrome is raising new questions about the long-term safety of common treatments. Researchers found that some widely used medications—including antidepressants and certain antidiarrheal drugs—were linked to a small but noticeable increase in the risk of death over time.

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