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A surprising new study reveals that blocking a supposedly protective enzyme, Caspase-2, could actually backfire—raising the risk of chronic liver damage and cancer over time. Researchers found that without this enzyme, liver cells grow abnormally large and accumulate genetic damage, leading to inflammation, scarring, and eventually tumors, especially with age. While inhibiting Caspase-2 may offer short-term benefits, such as reducing fatty liver disease, the long-term consequences appear dangerous.
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ScienceDaily
An East Bay apartment complex has been bought at a price that's well below its prior value. Read more ›
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A PG&E Corp. unit has bought a San Jose building in a move to bolster the utility's South Bay operations. Read more ›
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Nanocap NovaBay Pharmaceuticals changed its name to Stablecoin Development Corporation. Read more ›
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If you're still recovering from last week's DLSS 5 nightmare and Crimson Desert's gen-AI fiasco, we're sorry to re-open old wounds by telling you that Square Enix has announced it's teaming up with Google to put Gemini AI into Dragon Quest X. Read more Read more ›
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A newly surfaced internal 1999 Apple campus video of Steve Jobs provides a rare, unfiltered look at the company's post-turnaround strategy. The video is a recording of a July 27, 1999 employee gathering at Apple's Cupertino campus, uploaded by former Apple software engineer Akira Nonaka, who worked at Apple from 1991 to 2000. The 15-minute talk appears to have been recorded informally, likely by an employee present at the event,... Read more ›
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Few developers can - even after all this time - get you quite so swept up in their enthusiasm as Peter Molyneux. It's an enthusiasm that has, famously, got him into trouble in the past, when passion and promise have failed to meet reality by quite some margin - with players often caught in fallout. So it's hard not to be sceptical when it comes to 22 Cans and Molyneux's... Read more ›
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Microsoft has announced its next Xbox Partner Preview showcase will take place later this week, and focus on third-party games from the likes of Sega and GSC Game World. Read more Read more ›
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Когда говорят про RAG, обычно имеют в виду довольно прямую схему: взять документы, нарезать их на фрагменты, посчитать эмбеддинги, сложить всё в векторную базу и поверх этого подключить LLM. На демо это часто работает. Иногда работает и на корпоративных данных. Но на нормативных документах такой подход очень быстро начинает сыпаться.Мы увидели это на практике, когда строили систему для работы с нормативкой. Сначала задача выглядела стандартно: есть документы, есть вопросы пользователей,... Read more ›
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A 2025 American Society of Civil Engineers (ASCE) report gave U.S. infrastructure a "C" grade overall. However, one city has by far the worst roads. Read more ›
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As RAM and storage prices surge, smartphone brands may look to hybrid storage solutions like microSD cards to keep costs under control. Read more ›
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Давно хотелось написать материал-помощник для себя и коллег по подбору SCADA системы. Описать сам подход к выбору нужной технологии: с чего начать, что не упустить и как не перебрать. Читать далее Read more ›
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Microsoft has locked in its second games showcase of the year. A Xbox Partner Preview stream will take place on March 26 at 1PM ET. It'll be available on the Xbox YouTube and Twitch channels. There'll be dedicated Twitch and YouTube streams with ASL interpretation, another featuring British Sign Language and one with audio descriptions in English on the main Xbox YouTube channel. The YouTube stream will be in 4K... Read more ›
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The Schooldays.ie Teachers of Ireland Survey 2026, which gathered responses from 1,838 teachers across Early Years, Preschool, Primary, Secondary and Special Education, provides one of the most comprehensive snapshots of the profession in Ireland today. The research found that nearly three quarters of teachers describe themselves as either extremely proud or very proud to be […] Read more ›
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No, Azure Monitor did not just notify you, even though the mail came from its domain. Read more ›
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Software engineers embracing the AI coding revolution don’t have much loyalty to any particular coding tool, especially when a new, better one comes out. In the latest example of that, hundreds of engineers at Notion, a maker of popular task-management software, are abandoning coding tool Cursor for Anthropic’s Claude Code and OpenAI’s Codex, according to a person involved in the change.The switch at Notion is part of a broader trend,... Read more ›
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The plane was going just 24 miles per hour, proving just how impactful a 23-ton aircraft can be in a collision, and reminding U.S. airlines and airport operators just how important it is to get safety right. Read more ›
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British nutrition tech company Huel, known for its meal replacement kits, has agreed to be acquired by French food group Danone in a deal worth €1bn (£870m). Backed by celebrities including Idris Elba and Steven Bartlett, Huel was launched in 2015 by nutritionist James Collier and Julian Hearn. Huel eventually pulled in millions in investment, ... Read more ›
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Plus, Drew Goddard won't say whether or not Keanu Reeves will return for 'Matrix 5'. Read more ›
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The pilot and copilot of an Air Canada flight have died after colliding with a fire truck during landing. Read more ›
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Apple's early 2026 release schedule seems quite busy as the company has already announced upgraded MacBook Air and Pro models with M5 series chips, a new affordable MacBook Neo, iPad Air with M4 SoC and a pair of AirPods Max 2. And according to Mark Gurman, Apple is gearing up to announce an updated regular iPad. In the "Power On" newsletter, Mark Gurman says the upcoming iPad will be fitted... Read more ›
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ScienceDaily
A new UCLA Health study suggests that long-term exposure to the pesticide chlorpyrifos may dramatically raise the risk of Parkinson’s disease. Researchers found that people living in areas with sustained exposure had more than 2.5 times the likelihood of developing the disorder. Lab experiments reinforced the finding: animals exposed to the chemical developed movement problems, lost dopamine-producing neurons, and showed the same toxic protein buildup seen in Parkinson’s patients. Read more ›
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A redesigned cancer immunotherapy is showing striking early results after decades of disappointment with similar drugs. Researchers engineered a more powerful CD40 agonist antibody and changed how it’s delivered—injecting it directly into tumors instead of into the bloodstream. In a small clinical trial of 12 patients with metastatic cancers, six saw their tumors shrink and two experienced complete remission. Read more ›
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Scientists studying a mysterious effect called cosmic birefringence—a subtle twist in the polarization of the universe’s oldest light—have developed a new way to reduce uncertainty in how it’s measured. This faint rotation in the cosmic microwave background could point to entirely new physics, including hidden particles such as axions and clues about dark matter or dark energy. Read more ›
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Astronomers may have found an exciting new clue about dark energy—the mysterious force driving the universe’s accelerating expansion. They discovered an extraordinarily bright supernova from more than 10 billion years ago whose light was bent and magnified by a foreground galaxy, creating multiple images through gravitational lensing. Because the light from each image traveled slightly different paths, it arrived at Earth at different times, letting scientists effectively watch different moments... Read more ›
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mRNA vaccines saved millions of lives during COVID-19 but have limitations like waning immunity and complex production. Scientists are now testing a new platform called DoriVac, which uses folded DNA nanostructures to better control how the immune system responds. In early studies, it produced strong antibody and T cell responses in both mice and human models. Researchers say it could lead to more stable, easier-to-manufacture vaccines for diseases like COVID-19,... Read more ›
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The James Webb Space Telescope has revealed new details in a bizarre nebula that looks like a brain floating in space. Formed by a dying star, the “Exposed Cranium” nebula shows layered gas and a dark central divide that creates its eerie shape. Webb’s infrared view suggests powerful jets may be shaping the structure. The images capture a brief and dramatic phase in a star’s final evolution. Read more ›
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Researchers have identified a surprising brain pattern that may help explain why people with ADHD often struggle to stay focused. Even while awake, their brains can slip into brief episodes of “sleep-like” activity during demanding tasks. These moments are linked to more mistakes, slower reaction times, and lapses in attention. Read more ›
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A mysterious metal-rich asteroid called Psyche has been baffling scientists for over two centuries, and its true origin remains one of the biggest unanswered questions in planetary science. Is it the exposed core of a failed planet, or a chaotic mix of rock and metal forged through countless violent collisions? To find out, researchers simulated how a massive crater near Psyche’s north pole formed, revealing that the asteroid’s internal “porosity”... Read more ›
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A key Alzheimer’s drug has finally revealed its secret. Researchers discovered that lecanemab works by activating the brain’s immune cells—but only through a specific part of the antibody called the Fc fragment. This piece acts like a trigger, prompting microglia to clear harmful amyloid plaques. The finding could reshape how future Alzheimer’s therapies are designed. Read more ›
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Astronomers have identified a strange new kind of exoplanet that challenges how scientists classify worlds beyond our Solar System. The planet, L 98-59 d, appears to contain a vast ocean of molten rock beneath its surface that traps large amounts of sulfur deep inside. Observations from the James Webb Space Telescope revealed unusual sulfur-rich gases in its atmosphere and a surprisingly low density for its size. Read more ›
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23.03.2026 10:39
Last update: 10:30 EDT.
News rating updated: 16:31.
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