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Scientists at Oregon Health & Science University have developed a new molecule that could open the door to treating triple-negative breast cancer, one of the most aggressive and difficult-to-treat forms of the disease. The compound, called SU212, targets and disables a key enzyme that cancer cells rely on to fuel their growth. In tests using humanized mouse models, the molecule caused tumors to shrink and slowed the spread of cancer by forcing the enzyme to break down.
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An East Bay apartment complex has been bought at a price that's well below its prior value. Read more ›
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A PG&E Corp. unit has bought a San Jose building in a move to bolster the utility's South Bay operations. Read more ›
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The designs for two Xbox controllers have leaked online, offering a first look at Microsoft's new Xbox Elite Series 3 and a cloud gaming controller. Read more ›
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A member of a crime syndicate that tried to smuggle cocaine hidden inside printers has been sentenced to nine years behind bars. Read more ›
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Codex on mobile won't make you type Python on an Android phone, but it might save your commute. Read more ›
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The Crimson Desert team only recently released an update which allowed you to mount iguanas and other fantastic beasts, but it is already back at it, releasing a new patch which, among other things, adds more bosses to the rematch system meaning you can fight them again and again. Read more Read more ›
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Africa Tech Summit London, the leading African tech conference in Europe, today announced 13 investor-ready ventures selected to showcase their solutions at the London Stock Exchange on May 29, 2026. The landmark 10th edition brings together 350+ African and International ventures, investors, corporates, and regulators, including Shekel Mobility, London Stock Exchange, Goodwin, Tola, Verto, Loobv, […] Read more ›
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CFTC chairman Michael Selig sat down with WIRED to discuss how the agency scours Polymarket and other prediction markets for illegal activity. Read more ›
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![[Перевод] Почему сеньор-разработчик не может донести ценность своего опыта](https://times42.com/media/7/6/0/12431760_640x200.jpg "[Перевод] Почему сеньор-разработчик не может донести ценность своего опыта")
Какие чувства возникают у вас при прочтении такого предложения?«ИИ-агенты — будущее разработки ПО. Нам больше не нужны разработчики, замедляющие прогресс бизнеса».Если вы сеньор-разработчик и считаете, что оно верное, то у меня появляются подозрения о вашем опыте (ниже я объясню, почему).Но если вы не сеньор-разработчик, то я считаю, что вы правы.А? Что здесь происходит?Суть копирайтинга заключается в соотнесении послания и его аудитории.Поэтому для меня, копирайтера, в этом случае одно и то... Read more ›
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В рамках задачи по обработке XBRL-таксономий возникло требование: если таксономия удалена до обработки событий расчёта кэша, эти события не должны приводить к созданию данных для уже неактуальной сущности.На первый взгляд кажется, что достаточно найти соответствующие сообщения и удалить их из Kafka topic. Но Kafka хранит данные как commit log, поэтому точечное удаление сообщений по версии таксономии или другому бизнес-признаку оказывается небезопасным.В статье рассмотрим, почему прямое удаление сообщений не Read more ›
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Dan Diasio, EY's consulting CTO of Americas, said that the work of data, software, and AI engineers is overlapping much more today. Read more ›
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Heavy trading volume ahead of the ex-dividend date pushed STRC to its busiest session on record. Read more ›
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С осени прошлого года идет стремительный переход от использования ИИ в качестве личного помощника к встраиванию ИИ-агентов в команду и передачи им определенных задач – переход от вайбкодинга к agentic engineering. Задача, как это часто бывает, решается экспериментально, методом проб и ошибок, потому что организовывать разделение труда даже между людьми в команде тимлидов, да и большинство руководителей следующих уровней не учили. А в случае ИИ-агентом ситуация осложняется тем, что это... Read more ›
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Wisconsin Gov. Tony Evers signed an executive order Thursday (May 14) blocking state employees from using confidential government information to… Continue reading Gov. Evers bars Wisconsin employees from exploiting insider information through prediction markets Read more ›
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AI is changing everything about consulting, from how consultants do client work to how employees are trained, promoted, and measured. Read more ›
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Threat hunting is about resilience, challenging the assumption that existing tools will catch everything. Read more ›
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В предыдущих частях серии мы разобрали, как читать планы выполнения через EXPLAIN ANALYZE, и научились автоматически ловить медленные запросы с помощью pg_stat_statements, auto_explain и log_min_duration_statement. Теперь — следующий шаг: что делать с проблемами, которые вы нашли.В этой части разбираем три рычага оптимизации: статистику планировщика, индексы и рефакторинг SQL-запросов. На демонстрационном примере покажем, как снизить стоимость запроса почти вдвое — без изменений в инфраструктуре.Оборудовани Read more ›
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ScienceDaily
A common constipation drug may have unexpectedly unlocked a new way to slow chronic kidney disease — a condition that affects millions and often leads to dialysis. In a clinical trial involving 150 patients, researchers found that lubiprostone, a medication normally used to treat constipation, helped preserve kidney function in people with moderate CKD. Scientists traced the effect to changes in gut bacteria that boosted production of spermidine, a compound... Read more ›
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Scientists have uncovered a surprising secret hidden inside fat cells that could reshape how we think about obesity and metabolic disease. A protein called HSL, long believed to simply release stored fat when the body needs energy, turns out to have a second job deep inside the nucleus of fat cells—helping keep those cells healthy and balanced. Even more surprising, people and mice missing this protein don’t become obese as... Read more ›
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Scientists studying axolotls, zebrafish, and mice have uncovered a shared set of genes that may one day help humans regrow lost limbs. By identifying powerful “SP genes” involved in regeneration, researchers discovered that disabling these genes stopped proper bone regrowth in salamanders and mice. They then used a gene therapy inspired by zebrafish biology to partially restore regeneration in mice, marking a major step toward future treatments that could replace... Read more ›
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Scientists in China discovered that ancient humans were making surprisingly advanced stone tools during a harsh ice age 146,000 years ago. The tools, created by Homo juluensis, show careful planning and complex thinking rather than simple stone-chipping. Researchers dated the site using tiny calcite crystals inside animal bones, revealing the tools are much older than expected. The discovery challenges the idea that human creativity only thrives in easy, prosperous times. Read more ›
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Fur seals may look like they’re simply resting after exhausting hunting trips at sea, but their bodies are secretly working overtime. Scientists discovered that hours after returning to land, the seals’ heart rates suddenly surge — sometimes doubling — as they recover from the intense physical stress of deep diving. The findings suggest that seals postpone much of their recovery until they’re safely ashore, likely flushing out lactic acid and... Read more ›
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Scientists may have found a smarter, safer way to wipe out termites hiding inside homes. A chemical called bistrifluron prevents drywood termites from forming new exoskeletons during molting, killing entire colonies from within. In tests, it eliminated about 95% of termites while avoiding the toxic side effects of traditional fumigation. Researchers say the method could provide longer-lasting protection as termites spread into new areas. Read more ›
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Physicists may have just cracked open a hidden side of the quantum world. For decades, every known particle was thought to belong to one of two categories — bosons or fermions — but researchers have now shown that bizarre “in-between” particles called anyons could also exist in a one-dimensional system. Even more exciting, these strange particles may be adjustable, allowing scientists to tune their behavior in ways never before possible. Read more ›
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A new study shows that listening to your own favorite workout music can dramatically boost endurance. Cyclists exercising with self-selected songs lasted nearly 20% longer than when riding in silence, yet they didn’t feel more exhausted at the end. Researchers say music may help people stay in the “pain zone” longer without increasing perceived strain. Read more ›
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A major obstacle may be standing in the way of the next generation of ultra-tiny computer chips. Researchers discovered that many promising 2D materials lose their advantages because an invisible atomic-scale gap forms when they are combined with insulating layers. That tiny gap weakens electronic performance and could prevent further miniaturization. The team says new “zipper materials” that lock together more tightly may offer a path forward. Read more ›
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Scientists have taken a major step toward ultra-secure quantum communication by demonstrating a remarkably stable quantum encryption system that worked across more than 120 kilometers of optical fiber. Using tiny semiconductor quantum dots that emit single particles of light on demand, the team achieved one of the highest secure key rates yet for this type of technology while maintaining continuous operation for over six hours without manual adjustments. Read more ›
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15.05.2026 05:56
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