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Scientists at Oregon Health & Science University have developed a new molecule that could open the door to treating triple-negative breast cancer, one of the most aggressive and difficult-to-treat forms of the disease. The compound, called SU212, targets and disables a key enzyme that cancer cells rely on to fuel their growth. In tests using humanized mouse models, the molecule caused tumors to shrink and slowed the spread of cancer by forcing the enzyme to break down.
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ScienceDaily
An East Bay apartment complex has been bought at a price that's well below its prior value. Read more âș
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A PG&E Corp. unit has bought a San Jose building in a move to bolster the utility's South Bay operations. Read more âș
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Meta is using detailed tracking of employee activity to train AI systems that could eventually take over routine workplace tasks Read more âș
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The ability to sense a room's mood shift before anyone else isn't intuition â it's a detection skill learned in childhood, often at a real cost. Here's what the research actually says. Read more âș
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Most conversations about morning discipline start with what you should add. Wake up at 5am. Meditate for 20 minutes. Jump in a cold shower. Journal three pages. The self-improvement internet has turned the first hour of the day into a performance, a checklist of virtuous suffering. But thereâs a quieter, more fundamental discipline hiding underneath ... Read more Read more âș
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Indiaâs New Online Gaming Regime Indiaâs gaming landscape is bracing for a reset. Yesterday, MeitY notified the Online Gaming Act,⊠Read more âș
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A retired electrician in his 60s reflects on watching his granddaughter expect good things to happen, and confronts the lifetime of anticipatory anxiety he inherited from his own father â and what the research actually says you can and can't pass down. Read more âș
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Connections is a New York Times word game that's all about finding the "common threads between words." How to solve the puzzle. Read more âș
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The New York Times' latest game, Pips, brings domino fun to your desktop. How to play Pips as well as hints in case you get stuck. Read more âș
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Connections: Sports Edition is a New York Times word game about finding common sports threads between words. How to solve the day's puzzle. Read more âș
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The NYT Strands hints and answers you need to make the most of your puzzling experience. Read more âș
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Here's the answer for "Wordle" #1769 on April 23 as well as a few hints, tips, and clues to help you solve it yourself. Read more âș
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An anonymous survey of 129 WA founders has prompted StartupWA to call the problem "an ecosystem issue," and Meshpoints is putting $150,000 on the table to help find ideas that help. Read more âș
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On Wednesday, President Donald Trump claimed to have secured the release of eight Iranian women condemned to execution for protesting the regime. Only the night before, he had posted on Truth Social about the imminent executions of these women, quoting a screenshot that included a collage of eight glamorously backlit, soft-focus portraits. The photos of [âŠ] Read more âș
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ĐĐŸŃĐ° ĐżŃĐžĐ·ĐœĐ°ŃŃ, ŃŃĐŸ ĐșŃĐ»ŃŃ ĐœĐ”ĐŽĐŸŃŃпа â ŃŃĐŸ ĐœĐ” ĐżŃĐžĐ·ĐœĐ°Đș Đ°ĐŒĐ±ĐžŃĐžĐč, Đ° ĐżŃĐžĐ·ĐœĐ°Đș ĐżĐ»ĐŸŃ ĐŸĐłĐŸ ŃĐżŃĐ°ĐČĐ»Đ”ĐœĐžŃ ŃĐŸĐ±ĐŸĐč.ĐĐ”ŃŃĐČĐŸĐČĐ°ŃŃ ŃĐœĐŸĐŒ ĐŽĐŸ ŃĐžŃ ĐżĐŸŃ ŃŃĐžŃĐ°Đ”ŃŃŃ ŃĐ”ĐŒ-ŃĐŸ ĐżĐŸŃŃĐž ĐœĐŸŃĐŒĐ°Đ»ŃĐœŃĐŒ ŃŃДЎО ŃĐŸŃŃŃĐŽĐœĐžĐșĐŸĐČ, ĐŒĐ”ĐœĐ”ĐŽĐ¶Đ”ŃĐŸĐČ, ŃŃĐșĐŸĐČĐŸĐŽĐžŃДлДĐč, ĐżŃДЎпŃĐžĐœĐžĐŒĐ°ŃДлДĐč Đž ŃĐ°ĐŒĐŸĐ·Đ°ĐœŃŃŃŃ . ĐĄĐœĐ°Ńала ĐœĐ”ĐŒĐœĐŸĐłĐŸ ĐŽĐŸŃабаŃŃĐČĐ°Đ”ŃŃ ĐČĐ”ŃĐ”ŃĐŸĐŒ. ĐĐŸŃĐŸĐŒ Đ·Đ°ĐŽĐ”ŃжОĐČĐ°Đ”ŃŃŃŃ, ŃŃĐŸĐ±Ń ŃЎДлОŃŃ ĐČŃĐ”ĐŒŃ ĐœĐ° ŃДбŃ. ĐĐŸŃĐŸĐŒ ĐżŃĐžĐČŃĐșĐ°Đ”ŃŃ Đ¶ĐžŃŃ ĐČ ŃĐ”Đ¶ĐžĐŒĐ”, гЎД Đ±ĐŸĐŽŃŃŃĐČĐŸĐČĐ°ĐœĐžŃ ĐČŃĐŸĐŽĐ” Đ±Ń ĐŒĐœĐŸĐłĐŸ, Đ° ŃŃĐœĐŸŃŃĐž, ŃŃŃĐŸĐčŃĐžĐČĐŸŃŃĐž Đž ŃĐ°ĐŒĐŸĐșĐŸĐœŃŃĐŸĐ»Ń, ĐČŃĐ” ĐŒĐ”ĐœŃŃĐ”.ĐŃĐž ŃŃĐŸĐŒ ĐŸŃĐČĐ”ĐŽĐŸĐŒĐ»Đ”ĐœĐœĐŸŃŃŃ ĐŸ ĐČĐ°Đ¶ĐœĐŸŃŃĐž ŃĐœĐ° ŃĐ°ŃŃĐ”Ń. ĐĐŸ ĐŽĐ°ĐœĐœŃĐŒ ĐłĐ»ĐŸĐ±Đ°Đ»ŃĐœĐŸĐłĐŸ ĐŸ Read more âș
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Tesla CEO Elon Musk said he expects production for Optimus, the humanoid robot, to start around late July or August. Read more âș
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OpenAIâs latest image generator has thinking capabilities. ChatGPT Images 2.0 arrives one year after version 1.0, and it promises expertly curated end-to-end automation for visual tasks. Images 2.0 has the ability to research and synthesize information from the web into detailed âproduction-levelâ visuals. GPT Images 2.0 generated content OpenAI is positioning Images 2.0 as a full replacement for dedicated image editing apps, too, as it can remove backgrounds, transform aspect... Read more âș
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The mystery of what kind of CEO John Ternus will be for Apple may already have been solved by his own words. Read more âș
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Also, Musk owns up to a broken promise and vows to spend an unbelievably large amount of money to make up for it. Read more âș
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ScienceDaily
A long-running dinosaur mystery may finally be solved: Nanotyrannus, once dismissed as just a teenage T. rex, appears to have been its own distinct species after all. Scientists analyzed a tiny throat bone from the original fossil and discovered growth patterns showing the animal was already mature, not a juvenile giant-in-the-making. This smaller predatorâabout half the size of a full-grown T. rexâlikely roamed alongside its famous cousin, adding a new... Read more âș
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A surprising new clinical trial has revealed that metforminâa cheap, century-old drug widely used for type 2 diabetesâmay help people with type 1 diabetes in an unexpected way. While researchers initially hoped it would reduce insulin resistance, they instead found it allows patients to use about 12% less insulin while maintaining stable blood sugar levels. Read more âș
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New research suggests that aiming for a lower blood pressure target may deliver bigger heart health benefits than previously thought. Using large datasets and simulation models, scientists found that keeping systolic blood pressure below 120 mm Hg could reduce the risk of heart attack, stroke, and heart failure more than higher targets. Read more âș
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Scientists have discovered that methane in the open ocean is produced by microbes under nutrient-poor conditions, solving a long-standing mystery. As warming oceans reduce nutrient mixing, these methane-producing microbes may thrive. This could lead to increased methane emissions from the sea. The result is a potential feedback loop that could intensify climate change. Read more âș
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A massive, nearly 20-year study tracking over 650,000 Americans with irritable bowel syndrome is raising new questions about the long-term safety of common treatments. Researchers found that some widely used medicationsâincluding antidepressants and certain antidiarrheal drugsâwere linked to a small but noticeable increase in the risk of death over time. Read more âș
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Researchers have discovered lithium hidden in pyrite within ancient shale rocksâan unexpected find that could reshape how we source this critical battery material. It raises the possibility of extracting lithium from existing waste, reducing the need for new mining. Read more âș
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The ozone layer has been on track to recover thanks to the Montreal Protocolâbut a loophole may be holding it back. Chemicals still permitted for industrial use are leaking into the atmosphere at higher rates than expected. Scientists now estimate this could delay ozone recovery by up to seven years. Closing this gap could speed up healing and reduce harmful UV exposure worldwide. Read more âș
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A rogue set of âzombieâ immune cells may be driving aging and fatty liver disease by flooding tissues with inflammation. Researchers found these cells accumulate with age and high cholesterolâand can make up most of the liverâs immune cells in older mice. When scientists removed them, liver damage was dramatically reversed, even without diet changes. Read more âș
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Scientists have discovered that a protein linked to cell death is secretly driving the aging of blood stem cells in a completely different way. Instead of killing the cells, it damages their mitochondria, sapping their energy and weakening the immune system over time. When this protein was turned off, stem cells remained stronger and more balanced, even under stress. The findings point to a new strategy for slowing aging at... Read more âș
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Researchers have found a way to make cancer-killing immune cells more powerful and precise. By adding specific signaling components, they boosted the cellsâ readiness to attack tumors. Surprisingly, briefly suppressing the cells with a drug before use made them even more effective later. The approach could help create safer, stronger next-gen cancer treatments. Read more âș
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22.04.2026 23:13
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