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334 Menopause linked to grey matter loss in key brain regions

ScienceDaily
ScienceDaily · 02/07/2026 09:52 EDT

A major study suggests menopause is linked to changes in brain structure, mental health, and sleep. Brain scans revealed grey matter loss in areas tied to memory and emotional regulation, while many women reported increased anxiety, depression, and fatigue. Hormone therapy did not reverse these effects, though it may slow age-related declines in reaction speed. Researchers say menopause could represent an important turning point for brain health.

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