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Researchers revealed that the microbial metabolite TMA can directly block the immune protein IRAK4, reducing inflammation and improving insulin sensitivity. The molecule counteracts damage caused by high-fat diets and even protects mice from sepsis. Since IRAK4 is a known drug target, this pathway could inspire new diabetes therapies. The study highlights how gut microbes and nutrition can work together to support metabolic health.
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ScienceDaily
Lou Gerstner, who led IBM's 1990s turnaround, has died, the company told staff. Read more âș
1,185 fresh
OpenAI CEO Sam Altman warned on X that the job would be "stressful" and they'll need to "jump into the deep end pretty much immediately." Read more âș
951 fresh
Drinking water in plastic bottles contains countless particles too small to see. New research finds that people who drink water from them on a daily basis ingest far more microplastics than those who donât. Read more âș
803
Do you like the 'Fallout' games or show enough to watch a competition show based on 'Fallout Shelter'? Read more âș
685 fresh
Facing a global memory shortage, Asus may consider DRAM production or alternative suppliers to limit price hikes as DDR4 and DDR5 costs continue rising. Read more âș
582 fresh
Artist Keith Thomson is a modern (and whimsical) Edward Hopper. And Apple TV says he created the "festive artwork" shared on X by Apple CEO Tim Cook on Christmas Eve, "made on MacBook Pro." Its intentionally-off picture of milk and cookies was meant to tease the season finale of Pluribus. ("Merry Christmas Eve, Carol..." Cook had posted.) But others were convinced that the weird image was AI-generated. Tech blogger John... Read more âș
508 fresh
Yesterday, the ground shook off the coast of Taiwan, slamming the country with the strongest earthquake in 27 years. The seismic wave registered 7.0 in Taiwan's scales, or 6.6 to 6.7 according to the USGS standard. Thankfully, according to reports, TSMC's factories are all intact, saving the world from yet another spike in chip prices. Read more âș
442 fresh
HKC is bringing a 1,080 Hz gaming monitor to CES under its AntGamer brand, showing off a native 1440p 540 Hz panel that can use dual-mode to switch to a blistering 1,080 Hz at 720p. It's a Fast TN panel that is supposed to have DP 2.1 UHBR20 support. Read more âș
386 fresh
Apple isn't ready to pay a several billion-dollar fine to UK App Store users and is filing an appeal over a major antitrust lawsuit. As first reported by The Guardian, Apple has requested to appeal to the UK's Court of Appeal, which would escalate the case beyond the Competition Appeal Tribunal (CAT). The latest appeal attempt follows an October decision from the CAT, where the court found that Apple engaged... Read more âș
379 fresh
ĐŃДЎŃŃĐ°ĐČŃŃĐ”, ŃŃĐŸ ĐČĐ°ĐŒ ŃĐșазалО: «ĐŃĐŸĐłĐŸ ĐœĐ” ŃŃŃĐ”ŃŃĐČŃĐ”Ń, ĐżŃĐŸŃŃĐŸ Đ·Đ°ĐżĐŸĐŒĐœĐžÂ». ĐĐœĐŸĐłĐžĐ” Оз ĐČĐ°Ń ŃĐ»ŃŃалО ŃŃĐŸ ĐČ ŃĐșĐŸĐ»Đ” ОлО ĐČ ĐČŃĐ·Đ”, ĐșĐŸĐłĐŽĐ° ŃĐ”ŃŃ Đ·Đ°Ńла ĐŸ ĐșĐŸŃĐœĐ” Оз ĐŒĐžĐœŃŃ Đ”ĐŽĐžĐœĐžŃŃ. Đ ĐșĐŸĐŒĐżĐ»Đ”ĐșŃĐœŃŃ ŃĐžŃĐ»Đ°Ń ĐČĐ°ĐŒ ĐłĐŸĐČĐŸŃОлО ĐșĐ°Đș ĐŸ ĐČĐŸĐŸĐ±ŃĐ°Đ¶Đ°Đ”ĐŒŃŃ Đž ĐżŃДЎлагалО Ń ĐœĐžĐŒĐž ŃĐ°Đ±ĐŸŃĐ°ŃŃ Đ°Đ±ŃŃŃĐ°ĐșŃĐœĐŸ, ĐșĐ°Đș Ń ĐŒĐ°ŃĐ”ĐŒĐ°ŃĐžŃĐ”ŃĐșĐŸĐč ŃĐžĐșŃОДĐč, ĐșĐŸŃĐŸŃĐŸĐč ĐœĐ”Ń ĐČ ĐżŃĐžŃĐŸĐŽĐ”.ĐŁ ĐŒĐœĐŸĐłĐžŃ ŃŃĐŸ ĐČŃĐ·ĐČĐ°Đ»ĐŸ ĐŸĐżŃĐ”ĐŽĐ”Đ»Đ”ĐœĐœŃŃ ŃŃĐ°ĐČĐŒŃ, ĐŸŃĐžĐ±ĐŸŃĐœĐŸĐ” ĐŸŃĐœĐŸŃĐ”ĐœĐžĐ” Đș ĐșĐŸĐŒĐżĐ»Đ”ĐșŃĐœŃĐŒ ŃĐžŃĐ»Đ°ĐŒ ĐșĐ°Đș Đș ĐșĐ°ĐșĐŸĐč-ŃĐŸ ĐžĐ·ĐŸĐ±ŃĐ”ŃĐ”ĐœĐœĐŸĐč Đ»ŃĐŽŃĐŒĐž ĐČĐ”ŃĐž, ĐșĐŸŃĐŸŃĐŸĐč ĐœĐ”Ń ĐČ ĐżŃĐžŃĐŸĐŽĐ”. ĐĐŸ... Read more âș
294 fresh
An anonymous reader shared this report from The Guardian: A Texas father used the parental controls on his teenage daughter's cell phone to find and help rescue her after she was kidnapped at knifepoint while walking her dog on Christmas, authorities allege... Her father subsequently located her phone through the device's parental controls, the agency's statement said. The phone was about 2 miles (3.2km) away from him in a secluded,... Read more âș
242 fresh
After visiting all 50 states in the US, I've been pleasantly surprised by the amazing food at a few, including Connecticut, Wyoming, and Oregon. Read more âș
236 fresh
Sridhar Ramaswamy told Business Insider that while "meetings are like bureaucracies," he depends on them to make decisions. Read more âș
215 fresh
A US Navy special operations veteran told BI that ground robots are helpful, but it's best to have more cheap one than fewer expensive ones. Read more âș
192 fresh
Fully programmable, autonomous robots 'smaller than a grain of salt' have been developed by research teams from the University of Pennsylvania and the University of Michigan. Read more âș
179 fresh
An anonymous reader shared this report from the CBC: Cape Breton fiddler Ashley MacIsaac says he may have been defamed by Google after it recently produced an AI-generated summary falsely identifying him as a sex offender. The Juno Award-winning musician said he learned of the online misinformation last week after a First Nation north of Halifax confronted him with the summary and cancelled a concert planned for Dec. 19. "You... Read more âș
175 fresh
My grandmother's wedding letter felt strange at first, but months later her warning shaped how I understand marriage, forgiveness, and real partnership. Read more âș
152 fresh
The US president flies on Air Force One. World leaders in other countries also have their own official aircraft. Read more âș
134 fresh
An electronics technician succeeds in the most intricate gaming laptop motherboard repair we have seen completed. Read more âș
128 fresh
Many people asked me for money when my company made a million dollars. I often gave in, but it was never enough â until I set boundaries. Read more âș
121 fresh
ScienceDaily
Tramadol, a popular opioid often seen as a âsaferâ painkiller, may not live up to its reputation. A large analysis of clinical trials found that while it does reduce chronic pain, the relief is modestâso small that many patients likely wouldnât notice much real-world benefit. At the same time, tramadol was linked to a significantly higher risk of serious side effects, especially heart-related problems like chest pain and heart failure,... Read more âș
157
Alzheimerâs has long been considered irreversible, but new research challenges that assumption. Scientists discovered that severe drops in the brainâs energy supply help drive the diseaseâand restoring that balance can reverse damage, even in advanced cases. In mouse models, treatment repaired brain pathology, restored cognitive function, and normalized Alzheimerâs biomarkers. The results offer fresh hope that recovery may be possible. Read more âș
137
UBC Okanagan researchers have uncovered how plants create mitraphylline, a rare natural compound linked to anti-cancer effects. By identifying two key enzymes that shape and twist molecules into their final form, the team solved a puzzle that had stumped scientists for years. The discovery could make it far easier to produce mitraphylline and related compounds sustainably. It also highlights plants as master chemists with untapped medical potential. Read more âș
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A new eco-friendly technology can capture and destroy PFAS, the dangerous âforever chemicalsâ found worldwide in water. The material works hundreds to thousands of times faster and more efficiently than current filters, even in river water, tap water, and wastewater. After trapping the chemicals, the system safely breaks them down and refreshes itself for reuse. Itâs a rare one-two punch against pollution: fast cleanup and sustainable destruction. Read more âș
102
The familiar fight between âmind as softwareâ and âmind as biologyâ may be a false choice. This work proposes biological computationalism: the idea that brains compute, but not in the abstract, symbol-shuffling way we usually imagine. Instead, computation is inseparable from the brainâs physical structure, energy constraints, and continuous dynamics. That reframes consciousness as something that emerges from a special kind of computing matter, not from running the right program. Read more âș
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A new AI developed at Duke University can uncover simple, readable rules behind extremely complex systems. It studies how systems evolve over time and reduces thousands of variables into compact equations that still capture real behavior. The method works across physics, engineering, climate science, and biology. Researchers say it could help scientists understand systems where traditional equations are missing or too complicated to write down. Read more âș
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New research suggests Alzheimerâs may start far earlier than previously thought, driven by a hidden toxic protein in the brain. Scientists found that an experimental drug, NU-9, blocks this early damage in mice and reduces inflammation linked to disease progression. The treatment was given before symptoms appeared, targeting the disease at its earliest stage. Researchers say this approach could reshape how Alzheimerâs is prevented and treated. Read more âș
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Scientists discovered that common food emulsifiers consumed by mother mice altered their offspringâs gut microbiome from the very first weeks of life. These changes interfered with normal immune system training, leading to long-term inflammation. As adults, the offspring were more vulnerable to gut disorders and obesity. The findings suggest that food additives may have hidden, lasting effects beyond those who consume them directly. Read more âș
66
Deep ocean hot spots packed with heat are making the strongest hurricanes and typhoons more likelyâand more dangerous. These regions, especially near the Philippines and the Caribbean, are expanding as climate change warms ocean waters far below the surface. As a result, storms powerful enough to exceed Category 5 are appearing more often, with over half occurring in just the past decade. Researchers say recognizing a new âCategory 6â could... Read more âș
60
A shiny gray crystal called platinum-bismuth-two hides an electronic world unlike anything scientists have seen before. Researchers discovered that only the crystalâs outer surfaces become superconductingâallowing electrons to flow with zero resistanceâwhile the interior remains ordinary metal. Even stranger, the electrons on the surface pair up in a highly unusual pattern that breaks all known rules of superconductivity. Read more âș
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Business Insider
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31% 3 |
Wired
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23% 18 |
Tom's Hardware
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15% 4 |
Slashdot
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5% 1 |
TechRadar
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5% 2 |
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28.12.2025 16:51
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