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Scientists have uncovered how leukemia cells manage to escape one of the most commonly used treatments. Over time, these cancer cells subtly change the shape of their mitochondria to avoid dying when the drug tries to kill them. By identifying the protein that controls this shape-shifting, researchers were able to block it in mice, making the treatment powerful again and dramatically extending survival.
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Editor’s note, December 25, 8 am ET: This story is being republished for the holiday season. It was originally published in 2024. When I was about 7, Los Angeles public schools shifted to a “year-round” schedule. The effect, for my elementary school, was a shorter summer break (boo), and an extra-long winter break (also, it […] Read more ›
896 fresh
Whether it's proprietary charging or AI as a crutch for no hardware upgrades, I don't want to see these trends in 2026. Read more ›
796 fresh
Starlink satellite 35956 suffered from a serious anomaly on December 17. It has been pictured largely intact, tumbling in space, but it will be weeks before it burns up in the Earth's atmosphere. Read more ›
643 fresh
TSMC has shared a super-cool digital greetings card with a retro-nostalgic 8-bit style gaming animation. Read more ›
529 fresh
Christina Cassotis went from consulting to the CEO of a major airport. Here's how she got there and what passengers don't see. Read more ›
482 fresh
The $418 Smartlet literally bridges the gap between your elegant analogy and your nerdy smartwatch. Read more ›
468 fresh
AMD prepares EXPO 1.2 revision that could bring CUDIMM support to next-generation Ryzen processors. Read more ›
392 fresh
Taiwan’s iPass has released a new custom payment card that looks just like a Floppy Disk. Read more ›
358 fresh
Apple CEO Tim Cook bought $3 million in Nike shares, nearly doubling his stake in the company. Read more ›
340 fresh
Macy's, Kroger, and Carter's are leading 2026 US retail store closures, citing long-term strategy and shifting consumer habits. Read more ›
334 fresh
After a successful 2024 election, Vice President JD Vance came into the White House ready to shake things up, support President Donald Trump at all costs, and post whatever he wanted online. But what does Vance — the former “never Trump” conservative who has maneuvered, at least for now, into the position of MAGA heir […] Read more ›
311 fresh
The Midwest hasn't yet overthrown the Sun Belt as the next best region to move to. The 10 states that attracted more movers than they lost were largely in the Sun Belt. Read more ›
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This story was originally published in The Highlight, Vox’s member-exclusive magazine. To get early access to member-exclusive stories every month, join the Vox Membership program today. I wasn’t always a boring newsroom-bound editor. Back in my days as a Time magazine foreign correspondent, I used to fly to far-flung places, recorder and notebook in hand. That’s how, […] Read more ›
253 fresh
Slack makes it easy to determine which of your coworkers is sending the most messages. Read more ›
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Christmas Day famously belongs to football. This Dec. 25, there are three NFL games to watch: the Dallas Cowboys vs. Washington Commanders, the Detroit Lions vs. the Minnesota Vikings and the Denver Broncos vs. Kansas City Chiefs. Here's what you need to know about Thursday's football slate, and the rest of the Week 17 schedule. How to watch the NFL Christmas Day games: Date: Thursday, Dec. 25, 2025 Start times:... Read more ›
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Justin Pines, the CEO of the Jewish Broadcasting Service, initially took a "safe" career path in corporate law, before becoming a rabbi. Read more ›
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The winning numbers were white balls 4, 25, 31, 52, 59 and red Powerball 19. The Power Play multiplier was 2. Read more ›
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A major international review has upended long-held ideas about how top performers are made. By analyzing nearly 35,000 elite achievers across science, music, chess, and sports, researchers found that early stars rarely become adult superstars. Most world-class performers developed slowly and explored multiple fields before specializing. The message is clear: talent grows through variety, not narrow focus. Read more ›
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A new AI developed at Duke University can uncover simple, readable rules behind extremely complex systems. It studies how systems evolve over time and reduces thousands of variables into compact equations that still capture real behavior. The method works across physics, engineering, climate science, and biology. Researchers say it could help scientists understand systems where traditional equations are missing or too complicated to write down. Read more ›
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New research suggests Alzheimer’s may start far earlier than previously thought, driven by a hidden toxic protein in the brain. Scientists found that an experimental drug, NU-9, blocks this early damage in mice and reduces inflammation linked to disease progression. The treatment was given before symptoms appeared, targeting the disease at its earliest stage. Researchers say this approach could reshape how Alzheimer’s is prevented and treated. Read more ›
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For years, scientists thought Saturn’s moon Titan hid a global ocean beneath its frozen surface. A new look at Cassini data now suggests something very different: a thick, slushy interior with pockets of liquid water rather than an open sea. A subtle delay in how Titan deforms under Saturn’s gravity revealed this stickier structure. These slushy environments could still be promising places to search for life. Read more ›
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A small tweak to mitochondrial energy production led to big gains in health and longevity. Mice engineered to boost a protein that helps mitochondria work more efficiently lived longer and showed better metabolism, stronger muscles, and healthier fat tissue. Their cells produced more energy while dialing down oxidative stress and inflammation tied to aging. The results hint that improving cellular power output could help slow the aging process itself. Read more ›
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Researchers have revealed that so-called “junk DNA” contains powerful switches that help control brain cells linked to Alzheimer’s disease. By experimentally testing nearly 1,000 DNA switches in human astrocytes, scientists identified around 150 that truly influence gene activity—many tied to known Alzheimer’s risk genes. The findings help explain why many disease-linked genetic changes sit outside genes themselves. The resulting dataset is now being used to train AI systems to predict... Read more ›
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Long before whales and sharks, enormous marine reptiles dominated the oceans with unmatched power. Scientists have reconstructed a 130-million-year-old marine ecosystem from Colombia and found predators operating at a food-chain level higher than any seen today. The ancient seas were bursting with life, from giant reptiles to rich invertebrate communities. This extreme complexity reveals how intense competition helped drive the evolution of modern marine ecosystems. Read more ›
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Astronomers have detected spacetime itself being dragged and twisted by a spinning black hole for the first time. The discovery, seen during a star’s violent destruction, confirms a prediction made over 100 years ago and reveals new clues about how black holes spin and launch jets. Read more ›
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Researchers have found that fossilized dinosaur eggshells contain a natural clock that can reveal when dinosaurs lived. The technique delivers surprisingly precise ages and could revolutionize how fossil sites around the world are dated. Read more ›
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Balanophora is a plant that abandoned photosynthesis long ago and now lives entirely as a parasite on tree roots, hidden in dark forest undergrowth. Scientists surveying rare populations across East Asian islands uncovered how its cellular machinery shrank but didn’t disappear, revealing unexpected similarities to parasites like malaria. Some island species even reproduce without sex, cloning themselves to colonize new habitats. This strange survival strategy comes with risks, leaving the... Read more ›
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25.12.2025 09:44
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