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Researchers uncovered how estrogen subtly reshapes learning by strengthening dopamine reward signals in the brain. Rats learned faster when estrogen levels were high and struggled when the hormone’s activity was blocked. The findings help explain how hormonal cycles influence cognitive performance and psychiatric symptoms. This connection offers a new path for understanding brain disorders tied to dopamine.
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Trump says that $2,000 tariff checks are coming mid-2026. His GOP allies on Capitol Hill aren't so sure. Read more ›
993 fresh
Quick Share is finally compatible with AirDrop, plus an early look at the Galaxy Buds 4 Pro and Samsung’s take on Magic Cue. Read more ›
643 fresh
Users on X have benchmarked Nvidia's latest 581.94 hotfix driver that fixes performance issues stemming from Microsoft's October cumulative update for Windows 11. Read more ›
632 fresh
Last week one of my big questions about Pluribus was whether our reluctant hero Carol (Rhea Seehorn) would find someone to help her save the world from the scourge of happiness. In episode 4, I got an answer - sort of. We're clearly introduced to a character who thinks much like her, but how they'll […] Read more ›
560 fresh
The Black Friday sale on this popular slushie machine is the lowest price it's been since its release. Read more ›
413 fresh
A WWII Enigma encryption machine with four rotors was sold at auction earlier this week, achieving double its estimated price. Read more ›
403 fresh
Entrepreneur Dagobert Renouf funded his wedding by selling company logo spaces on his suit. The unusual idea led to a job in tech sales. Read more ›
385 fresh
You can make your RTX 5090 just a teeny bit more powerful and less efficient, thanks to a new 800W BIOS stripped from Asus' $4000 ROG Matrix RTX 5090. As long as you have a compatible 5090 that'll play nicely with the custom firmware, you, too, can enjoy higher clocks and electricity bills for a marginal increase in performance. Read more ›
378 fresh
Windows 1.01 was released by Microsoft 40 years ago. It didn't start well. Read more ›
354 fresh
Ubisoft has announced "Teammates", an "AI experiment to change the game" and "deepen the player experience". Read more Read more ›
324 fresh
Thousands of older Americans remain in sometimes risky jobs like driving and construction, some out of necessity and others to maintain purpose. Read more ›
321 fresh
After meeting in the Oval Office, Trump and NYC Mayor-elect Zohran Mamdani sounded a largely conciliatory note. Read more ›
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Wireless charging has become one of those small but satisfying conveniences of modern smartphones. You drop your device on a pad and watch the battery percentage climb without fiddling with cables or ports. Yet for many users, that effortless charge doesn’t always come at the speed they expect. Sometimes the phone warms up, the percentage barely rises or charging takes far longer than it would if you plugged it in.... Read more ›
298 fresh
Score a great gift for everyone on your list without breaking the bank. Every one of these gifts comes WIRED-recommended. Read more ›
284 fresh
My Arcade and Atari have put together a handheld retro gaming console graced by a bevy of unique retro-futuristic controls. However, the price, and a few hardware and software wrinkles, tarnish its appeal. Read more ›
263 fresh
Whether it's intentional or unintentional, most polled readers think OPPO is ruining OnePlus. Read more ›
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Harry Stebbings emailed Marc Benioff 53 times for a year, trying different techniques. It paid off with a 2023 podcast interview. Read more ›
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Get $800 off the Samsung Odyssey Neo G9 gaming monitor this Black Friday. The Samsung Odyssey Neo G9 gaming monitor is down to $1,499.99 at Amazon. Read more ›
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Google has brainwashed me into thinking this is all the functionality I need in a launcher. Read more ›
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Researchers found that tau proteins don’t jump straight into forming Alzheimer’s-associated fibrils—first they assemble into soft, reversible clusters. When the clusters were dissolved, fibril growth was almost entirely suppressed. This reveals a promising new strategy: stop the precursors, stop the disease. Read more ›
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Rutgers scientists found that metformin can blunt many of the metabolic and cardiovascular improvements normally produced by exercise. Participants who took the drug saw reduced gains in fitness, blood vessel function, and glucose control. The interference may stem from how metformin affects mitochondrial activity. Read more ›
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Older adults who regularly listen to or play music appear to have significantly lower risks of dementia and cognitive decline. The data suggests that musical engagement could be a powerful, enjoyable tool for supporting cognitive resilience in aging. Read more ›
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Chronic kidney disease has surged to nearly 800 million cases and is now among the top causes of death worldwide. The condition is heavily linked to diabetes, hypertension, and obesity, and often goes unnoticed until late stages. Many countries lack access to dialysis and transplants, leaving millions without adequate care. Read more ›
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Electrons can freeze into strange geometric crystals and then melt back into liquid-like motion under the right quantum conditions. Researchers identified how to tune these transitions and even discovered a bizarre “pinball” state where some electrons stay locked in place while others dart around freely. Their simulations help explain how these phases form and how they might be harnessed for advanced quantum technologies. Read more ›
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Scientists discovered that alcohol activates a sugar-producing pathway in the body, creating fructose that may reinforce addictive drinking. The enzyme responsible, KHK, appears to drive both alcohol cravings and liver injury. When this enzyme was blocked in mice, their drinking decreased and their livers showed far less damage. Read more ›
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Scientists found that people who use both cannabis and tobacco show a distinct brain pattern tied to mood and stress regulation. Their scans revealed higher levels of an enzyme that reduces a natural feel-good molecule in the brain. This imbalance may help explain why co-users experience more anxiety and struggle more when quitting. Read more ›
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GLP-1 drugs like tirzepatide and semaglutide offer powerful weight-loss effects but come with unanswered questions about long-term safety, side effects, and global accessibility. Researchers stress the need for independent studies before these treatments can be fully embraced worldwide. Read more ›
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People are more likely to believe lies when there’s the possibility of a reward. Neuroimaging shows that the brain shifts into reward or risk mode depending on whether the context involves a gain or a loss. Friends show synchronized brain activity that can predict successful deception. Social bonds and incentives can subtly warp how we judge honesty. Read more ›
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Ultra-processed foods, already known for their links to health problems in adults, are now shown to harm young adults too, disrupting blood sugar regulation long before illness appears. A four-year USC study following 85 participants found that even modest increases in UPF consumption drove up the risk of prediabetes and insulin resistance, two early markers that pave the way for type 2 diabetes. Read more ›
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22.11.2025 09:46
Last update: 09:41 EDT.
News rating updated: 16:41.
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