65 place 10 fresh
A specially engineered antibody that can infiltrate kidney cysts has shown the ability to block key growth signals driving polycystic kidney disease. Early mouse studies suggest it may halt or even reverse cyst expansion without harming healthy tissue.
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847 fresh
Cloudflare suffered its worst network outage in six years on Tuesday, beginning at 11:20 UTC. The disruption prevented the content delivery network from routing traffic for roughly three hours. The failure, writes Cloudflare in a blog post, originated from a database permissions change deployed at 11:05 UTC. The modification altered how a database query returned information about bot detection features. The query began returning duplicate entries. A configuration file used... Read more ›
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A federal judge in New York denied Disney’s request to block Sling TV’s short-term passes, which give viewers the ability to stream live content for as little as one day. In a ruling on Tuesday, US District Judge Arun Subramanian ruled that Disney didn’t prove that Sling TV’s passes caused “irreparable harm” to the entertainment […] Read more ›
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BONK slipped beneath a key support level amid a sharp rise in trading activity, with intraday charts now pointing toward a fragile short-term structure. Read more ›
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Scientists have developed a new molecule that breaks down beta-amyloid plaques by binding to excess copper in the brain. The treatment restored memory and reduced inflammation in rats, while also proving non-toxic and able to cross the blood–brain barrier. Because it’s far simpler and potentially cheaper than existing drugs, researchers are now pursuing partnerships to begin human trials. Read more ›
587 fresh
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In the face of heavy travel restrictions imposed by the Trump administration, the United States announced that soccer fans going to the World Cup will enjoy a certain priority for processing tourist visa. Read more ›
527 fresh
Researchers found that tau proteins don’t jump straight into forming Alzheimer’s-associated fibrils—first they assemble into soft, reversible clusters. When the clusters were dissolved, fibril growth was almost entirely suppressed. This reveals a promising new strategy: stop the precursors, stop the disease. Read more ›
162
Rutgers scientists found that metformin can blunt many of the metabolic and cardiovascular improvements normally produced by exercise. Participants who took the drug saw reduced gains in fitness, blood vessel function, and glucose control. The interference may stem from how metformin affects mitochondrial activity. Read more ›
137
Older adults who regularly listen to or play music appear to have significantly lower risks of dementia and cognitive decline. The data suggests that musical engagement could be a powerful, enjoyable tool for supporting cognitive resilience in aging. Read more ›
134
Researchers uncovered how fatty molecules called ceramides trigger acute kidney injury by damaging the mitochondria that power kidney cells. By altering ceramide metabolism or using a new drug candidate, the team was able to protect mitochondrial function and completely prevent kidney injury in mice. Read more ›
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Chronic kidney disease has surged to nearly 800 million cases and is now among the top causes of death worldwide. The condition is heavily linked to diabetes, hypertension, and obesity, and often goes unnoticed until late stages. Many countries lack access to dialysis and transplants, leaving millions without adequate care. Read more ›
103
Exercise appears to spark a whole-body anti-aging cascade, and scientists have now mapped out how it happens—and how a simple oral compound can mimic it. By following volunteers through rest, intense workouts, and endurance training, researchers found that the kidneys act as the hidden command center, flooding the body with a metabolite called betaine that restores balance, rejuvenates immune cells, and cools inflammation. Even more striking, giving betaine on its... Read more ›
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Researchers have designed a smart drug that hunts down and breaks a little-known RNA that cancer cells depend on. The drug recognizes a unique fold in the RNA and triggers the cell to destroy it. Tests showed that removing this RNA slows cancer growth. The approach could lead to new treatments that attack cancer at its most fundamental level. Read more ›
72
Electrons can freeze into strange geometric crystals and then melt back into liquid-like motion under the right quantum conditions. Researchers identified how to tune these transitions and even discovered a bizarre “pinball” state where some electrons stay locked in place while others dart around freely. Their simulations help explain how these phases form and how they might be harnessed for advanced quantum technologies. Read more ›
51
Scientists discovered that alcohol activates a sugar-producing pathway in the body, creating fructose that may reinforce addictive drinking. The enzyme responsible, KHK, appears to drive both alcohol cravings and liver injury. When this enzyme was blocked in mice, their drinking decreased and their livers showed far less damage. Read more ›
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Scientists found that people who use both cannabis and tobacco show a distinct brain pattern tied to mood and stress regulation. Their scans revealed higher levels of an enzyme that reduces a natural feel-good molecule in the brain. This imbalance may help explain why co-users experience more anxiety and struggle more when quitting. Read more ›
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19.11.2025 12:21
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