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Scientists identified a small molecule that interrupts a harmful protein pair linked to diabetic inflammation and tissue damage. The compound helped wounds heal faster and reduced organ stress in both Type 1 and Type 2 diabetes models. Unlike typical treatments, it works by blocking damaging signals rather than lowering sugar levels. The results point to a new direction for treating diabetes complications.
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ScienceDaily
According to the Financial Times, Tim Cook may be ready to leave his position as soon as next year, and Apple's board and senior executives have ramped up their preparations to secure his replacement. Cook, who has been at the helm of Apple for more than 14 years, succeeded Steve Jobs and led the company to a market cap of more than $4 trillion. Cook's tenure since 2011 has overseen... Read more ›
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Escape from Tarkov is sitting on a Mostly Negative rating today after yesterday's eagerly-awaited Steam debuted to stability and performance issues that prevent players even logging in, let alone play. Read more Read more ›
644 fresh
The bill to reopen the government kept lawmakers' salaries frozen at $174,000 a figure that hasn't budged since 2009. Read more ›
604 fresh
A PC repair tech has detailed how a $10,000 RTX Pro 6000 GPU reportedly snapped under its own weight, breaking the PCIe connector and rendering the card useless. Read more ›
483 fresh
Call of Duty: Black Ops 7's approach to its single-player campaign has got players complaining. Read more ›
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The 'RRR' and 'Baahubali' director is back with another action movie epic with the 2027-bound 'Varanasi.' Read more ›
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From LEDs to fancy OLED models, in 4K and beyond, these are our favorite televisions at every price. Read more ›
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X has replaced its longstanding DM feature with Chat, featuring end-to-end encryption, disappearing messages, and more. Read more ›
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For the past few weeks, conservatives have been having a heated and divisive debate about antisemitism and the sorts of characters that can or cannot be part of the Republican Party. At the center of this argument is a 27-year-old white supremacist and far-right political influencer who hosts an online show called America First with […] Read more ›
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Our first look at the cast of the live-action Legend of Zelda movie has leaked online. Read more Read more ›
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Jeff Bezos and Lauren Sánchez Bezos didn't just get married this year. They also reached fashion milestones together at gala events and red carpets. Read more ›
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I've lived in Minnesota for most of my life, but I decided to move to Oregon on a whim. I struggled to make friends, so I had to find my confidence. Read more ›
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No wonder Apple and Samsung are considering cancelling their next ultra-slim models. Read more ›
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Kathy Curtis, 81, who works part-time in customer service and data entry for a local water company, earns $18 an hour and lives frugally. Read more ›
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The sell-off is attributed to a combination of factors, including profit-taking, institutional outflows, macro uncertainty, and low liquidity. Read more ›
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"The International Energy Agency's latest outlook signals that oil demand could keep growing through to the middle of the century," reports CNBC, "reflecting a sharp tonal shift from the world's energy watchdog and raising further questions about the future of fossil fuels." In its flagship World Energy Outlook, the Paris-based agency on Wednesday laid out a scenario in which demand for oil climbs to 113 million barrels per day by... Read more ›
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The morning of Monday, October 27th, I started my workweek by asking my colleagues at The Verge for advice on buying a gaming PC. I wanted a small, portable, and semi-powerful machine that could easily sit beneath my living room TV and occasionally move over to my desk to play games or even use for […] Read more ›
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Neura aims to produce 5 million robots by 2030 and has already booked €1 billion in orders. Read more ›
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You may now have to scrutinize what you read on the internet (and event on print) more closely to determine if it’s the product of AI. Sam Altman has revealed on X that if you tell ChatGPT not to use em dashes in your custom instructions, the chatbot will now finally listen to you. Previously, ChatGPT would ignore your instruction and continue using em dashes even if you tell it... Read more ›
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This week, we review the OnePlus 15, analyze Android 17’s contact changes, and speculate about new Android XR gestures. Read more ›
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ScienceDaily
GLP-1 drugs such as Ozempic and Wegovy may extend the lives of colon cancer patients, according to a major UC San Diego study. Patients on the medications had less than half the mortality rate of non-users. Researchers suspect the drugs’ anti-inflammatory and metabolic effects contribute to improved outcomes. They’re now calling for clinical trials to test whether these findings reflect a true anti-cancer mechanism. Read more ›
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Researchers in Osaka have found that stem cells from fat tissue can repair spinal fractures similar to those caused by osteoporosis. By turning these cells into bone-forming clusters and pairing them with a bone-rebuilding material, rats regained stronger, healthier spines. The approach could offer a safe, minimally invasive alternative for treating bone diseases in humans. Read more ›
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Intermountain Health researchers discovered that customizing vitamin D3 doses for heart attack survivors slashed their risk of another heart attack by 50%. The strategy involved frequent monitoring and dose adjustments to reach ideal vitamin D levels. Traditional studies didn’t track blood levels, missing this critical link. Read more ›
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Exercise appears to spark a whole-body anti-aging cascade, and scientists have now mapped out how it happens—and how a simple oral compound can mimic it. By following volunteers through rest, intense workouts, and endurance training, researchers found that the kidneys act as the hidden command center, flooding the body with a metabolite called betaine that restores balance, rejuvenates immune cells, and cools inflammation. Even more striking, giving betaine on its... Read more ›
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In a first-of-its-kind study, scientists found that bumblebees can tell the difference between short and long light flashes, much like recognizing Morse code. The insects learned which signal led to a sweet reward, demonstrating an unexpected sense of timing. This ability may stem from a fundamental neural process, suggesting that even tiny brains have complex time-tracking mechanisms relevant to evolution and AI. Read more ›
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Researchers have designed a smart drug that hunts down and breaks a little-known RNA that cancer cells depend on. The drug recognizes a unique fold in the RNA and triggers the cell to destroy it. Tests showed that removing this RNA slows cancer growth. The approach could lead to new treatments that attack cancer at its most fundamental level. Read more ›
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New research finds that daily coffee drinking may cut AFib risk by nearly 40%, defying decades of medical caution. Scientists discovered that caffeine’s effects on activity, blood pressure, and inflammation could all contribute to a healthier heart rhythm. The DECAF clinical trial’s findings suggest coffee could be not only safe but beneficial for people with A-Fib. Read more ›
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Researchers discovered that continents don’t just split at the surface—they also peel from below, feeding volcanic activity in the oceans. Simulations reveal that slow mantle waves strip continental roots and push them deep into the oceanic mantle. Data from the Indian Ocean confirms this hidden recycling process, which can last tens of millions of years. Read more ›
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Researchers have discovered that prostate cancer depends on two key enzymes, PDIA1 and PDIA5, to survive and resist therapy. When blocked, these enzymes cause the androgen receptor to collapse, killing cancer cells and enhancing the effects of drugs like enzalutamide. They also disrupt the cancer’s energy system, striking it on multiple fronts. This breakthrough could open a new path to overcoming drug resistance in advanced prostate cancer. Read more ›
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Japanese researchers found that lecanemab, an amyloid-clearing drug for Alzheimer’s, does not improve the brain’s waste clearance system in the short term. This implies that nerve damage and impaired clearance occur early and are difficult to reverse. Their findings underscore that tackling amyloid alone may not be enough to restore brain function, urging a broader approach to treatment. Read more ›
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8% 2 |
Vox
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7% 3 |
Android Authority
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7% 5 |
CNET
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6% 4 |
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