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Scientists have pinpointed a “Big Bang” moment in bowel cancer—when cells first evade the immune system. This early immune escape locks in how the cancer will behave as it grows. The discovery could help predict which patients respond to immunotherapy and lead to new vaccine strategies
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ScienceDaily
AMD's Bulldozer-era FX-9590 CPU from 2013 managed to run Battlefield 6 at over 30 FPS at 1080p resolution, boosting to 40+ FPS at lower resolutions on smaller maps. FX-9590, despite being more than a decade old, does support SecureBoot, which was enough for BF6 launch, confirming TPM is not neccesary. Read more ›
876 fresh
In a wide-ranging interview conducted following this week's GTA 6 delay, Take-Two CEO Strauss Zelnick has admitted Borderlands 4's sales were "softer" than expected - blaming the dip on "challenges" with the heavily criticised PC release that Gearbox boss Randy Pitchford previously insisted had "few real issues", despite significant performance complaints. Read more Read more ›
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Elon Musk could become the world's first trillionaire, but first he needs to meet a series of ambitious goals. Read more ›
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David Kobrosky tells Business Insider he dropped out of college to start a business, which he sold by the age of 26. Read more ›
556 fresh
Record package of shares approved by 75% majority, reinforcing billionaire’s control of the electric-car maker Read more ›
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Legora's shared workspace, Portal, offers law firms a new line item on the revenue sheet. Read more ›
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I'm not married and I don't have kids, so I never felt the need to have a will. Now in my 50s, I'm glad I know where my money is going when I'm gone. Read more ›
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Tesla's biggest bulls were elated by the vote's outcome, while some investors were alarmed. Read more ›
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If you’re arrested in America for a minor charge — say, for speeding or loitering — the punishment from the legal system might end up being the least of your worries. You might wake up a few months later and see your arrest, filmed through a police body camera, with a million views on TikTok […] Read more ›
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The Big Apple has had a tech boom in the past few years—here’s where to stay, play, eat, and work in the city’s tech-dense Dumbo neighborhood. Read more ›
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Taco Bell's bright green Mountain Dew Baja Blast pie looks disgusting. But it's part of a strategy to reach Gen Z. And it's surprisingly good. Read more ›
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University of Galway has been awarded funding for 25 collaborative projects as part of the ENLIGHT European university alliance. Title photo From left, Aishling Hanrahan, ENLIGHT Engagement Manager; Kathryn Kozarits, ENLIGHT Executive; Alex Metcalfe, Vice President International; Louise Hannon, Head of Research, Post Award; and Pamela Devins, Head of ENLIGHT, University of Galway. Academics and […] Read more ›
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Other big tech companies including Amazon, Apple, and Nvidia have continued their annual disclosures this year even as the Trump administration cracks down on DEI. Read more ›
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Asus' new ROG Matrix RTX 5090 GPU is so big that it will ship with Level Sense technology at launch. The feature can detect a shift of just 0.10 degrees to help prevent GPU sag. Read more ›
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Since March of this year, it's been possible to generate images directly within ChatGPT. Following a period where it briefly wasn't available to free users, you now don't even pay for one of OpenAI's subscriptions to use the tool. And while making images inside of ChatGPT is easy, there are some nuances worth explaining. For example, did you know you can ask ChatGPT to edit photos you've taken? It's more... Read more ›
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Videos show UPS Flight 2976 banking left before the accident, and officials said the plane's left engine detached entirely during takeoff. Read more ›
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I fear Samsung's eye will be on the TriFold and it will adopt the laziest attitude for the Z Fold 8. Read more ›
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ScienceDaily
A team of scientists has developed a highly accurate blood test for Chronic Fatigue Syndrome. The test reads tiny DNA patterns that reveal the biological signature of the illness. For millions who’ve faced doubt and misdiagnosis, it’s a breakthrough that finally validates their experience — and may help diagnose long Covid too. Read more ›
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Scientists uncovered how the amino acid leucine enhances mitochondrial efficiency by preserving crucial proteins that drive energy production. By downregulating the protein SEL1L, leucine prevents unnecessary degradation and strengthens the cell’s power output. The findings link diet directly to mitochondrial health and suggest potential therapeutic applications for energy-related diseases. Read more ›
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Cognitive struggles are climbing across the U.S., especially among young and economically disadvantaged adults. Rates of self-reported cognitive disability nearly doubled in people under 40 between 2013 and 2023. Researchers suspect social and economic inequality plays a major role and are urging further study to understand the trend’s causes and long-term impact. Read more ›
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Meditation is widely praised for its mental health benefits, but new research shows that it can also produce unexpected side effects for some people—from anxiety and dissociation to functional impairment. Psychologist Nicholas Van Dam and his team found that nearly 60% of meditators experienced some kind of effect, and about a third found them distressing. Read more ›
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Astronomers have captured a haunting image of a “cosmic bat” spreading its wings across deep space. This nebula, 10,000 light-years away, glows crimson as newborn stars ignite clouds of gas and dust. Read more ›
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Disrupted sleep patterns in Alzheimer’s disease may be more than a symptom—they could be a driving force. Researchers at Washington University found that the brain’s circadian rhythms are thrown off in key cell types, changing when hundreds of genes turn on and off. This disruption, triggered by amyloid buildup, scrambles normal gene timing in microglia and astrocytes—cells vital for brain maintenance and immune defense. Read more ›
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Scientists have discovered that a “longevity gene” found in people who live beyond 100 can reverse heart aging in models of Progeria, a devastating disease that causes children to age rapidly. By introducing this supercentenarian gene into Progeria-affected cells and mice, researchers restored heart function, reduced tissue damage, and slowed aging symptoms. The discovery opens the door to new therapies inspired by the natural biology of long-lived humans—possibly reshaping how... Read more ›
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Beneath the ocean’s surface, bacteria have evolved specialized enzymes that can digest PET plastic, the material used in bottles and clothes. Researchers at KAUST discovered that a unique molecular signature distinguishes enzymes capable of efficiently breaking down plastic. Found in nearly 80% of ocean samples, these PETase variants show nature’s growing adaptation to human pollution. Read more ›
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Virginia Tech researchers have shown that memory loss in aging may be reversible. Using CRISPR tools, they corrected molecular disruptions in the hippocampus and amygdala, restoring memory in older rats. Another experiment revived a silenced memory gene, IGF2, through targeted DNA methylation editing. These findings highlight that aging brains can regain function through precise molecular intervention. Read more ›
42
After the collapse of the Chalcolithic culture around 3500 BCE, people in Jordan’s Murayghat transformed their way of life, shifting from domestic settlements to ritual landscapes filled with dolmens, standing stones, and megalithic monuments. Archaeologists from the University of Copenhagen believe these changes reflected a creative social response to climate and societal upheaval. Read more ›
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Most popular sources
Ars Technica
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23% 19 |
Business Insider
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18% 5 |
Gizmodo
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9% 5 |
Engadget
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9% 5 |
Financial Times
|
6% 3 |
| View sources » | |
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07.11.2025 08:59
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