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Weill Cornell researchers uncovered how free radicals from astrocyte mitochondria can fuel dementia. Using new compounds that target these radicals at their source, they slowed brain inflammation and neuronal damage in mice. The findings reveal a potential breakthrough for treating diseases like Alzheimer’s and frontotemporal dementia by focusing on the precise mechanisms driving degeneration.
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The smarter, more capable version of Siri that Apple is developing will be powered by Google Gemini, reports Bloomberg. Apple will pay Google approximately $1 billion per year for a 1.2 trillion parameter artificial intelligence model that was developed by Google. For context, parameters are a measure of how a model understands and responds to queries. More parameters generally means more capable, though training and architecture are also factors. Bloomberg... Read more ›
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Trump told Fox News that Mamdani gave "a very angry speech" on Tuesday night. The mayor-elect directly addressed Trump. Read more ›
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If you go all-in on a single feature, that feature should work well. The Viewsonic VG1656N's main feature isn't great, but it's uncommon at least. Read more ›
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I tasted dozens of mushroom teas, kava drinks, and party drinks to find the best. Brez and Juni are the two I recommend for most people looking for focus. Read more ›
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Neighbors complained about noise, security guards, and hordes of traffic. An unlicensed school named after the Zuckerbergs’ pet chicken tipped them over the edge. Read more ›
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Charlie Brown, a freelance writer living in Portugal, shared why she quit the Financial Independence, Retire Early movement after 6 years because of her ethical concerns. Read more ›
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Some parents think they have to follow certain rules, such as getting an early start. I prefer to break those rules when traveling with kids. Read more ›
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Jensen Huang, Yoshua Bengio, Geoffrey Hinton, Fei-Fei Li, Yann LeCun and Bill Dally talk to the FT’s AI editor Read more ›
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Years ago, billionaire Peter Thiel said that high student debt and the lack of affordable housing were causing young Americans to lose faith. Read more ›
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Paradox Interactive? Here's a bloody paradox for you! I love the idea of grand strategy games, perhaps more than I can possibly convey. I've spent countless hours poring over screenshots of Europa Universalis 4, Crusader Kings 3, and Victoria 3, mesmerised by those evocative maps and enigmatic numbers. Where some might see drab undulations and a spreadsheet UI, I see tantalising potential; the chance to bend history to my whims... Read more ›
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Republican lawmakers, right-wing influencers, far-right extremists, and conspiracy theorists pushed anti-immigrant and anti-Muslim rhetoric after Zohran Mamdani’s victory. Read more ›
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Amsterdam’s Struck secures €2M to expand its AI platform for simplifying construction compliance and permitting across Europe. Amsterdam-based Struck, a startup that simplifies compliance in construction, has secured €2M in seed funding. The round was led by Value Factory Ventures, with participation from Antler and business angels from the construction and real estate sectors. Struck ... Read more Read more ›
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Lint today, slipperiness tomorrow, long-term durability problems — this isn't a case worth $50. Read more ›
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The New York Times' latest game, Pips, brings domino fun to your desktop. How to play Pips as well as hints in case you get stuck. Read more ›
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Meta's stand-alone AI app has a video feed called Vibes. It's being taken over by Donald Trump memes and political stuff. I'm calling it "boomerslop." Read more ›
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The date for Starbucks' Red Cup Day 2025 has been announced. Find out when the event goes live and how to get your free cup. Read more ›
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This upcoming Google Maps toggle could be a lifesaver during heatwaves, or if you simply want to avoid the sun. Read more ›
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The phone is said to charge at higher wattages for much longer compared to its predecessors. Read more ›
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A team of scientists has developed a highly accurate blood test for Chronic Fatigue Syndrome. The test reads tiny DNA patterns that reveal the biological signature of the illness. For millions who’ve faced doubt and misdiagnosis, it’s a breakthrough that finally validates their experience — and may help diagnose long Covid too. Read more ›
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Scientists uncovered how the amino acid leucine enhances mitochondrial efficiency by preserving crucial proteins that drive energy production. By downregulating the protein SEL1L, leucine prevents unnecessary degradation and strengthens the cell’s power output. The findings link diet directly to mitochondrial health and suggest potential therapeutic applications for energy-related diseases. Read more ›
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Cognitive struggles are climbing across the U.S., especially among young and economically disadvantaged adults. Rates of self-reported cognitive disability nearly doubled in people under 40 between 2013 and 2023. Researchers suspect social and economic inequality plays a major role and are urging further study to understand the trend’s causes and long-term impact. Read more ›
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Astronomers have captured a haunting image of a “cosmic bat” spreading its wings across deep space. This nebula, 10,000 light-years away, glows crimson as newborn stars ignite clouds of gas and dust. Read more ›
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Earth’s magnetosphere, once thought to have a simple electric polarity pattern, has revealed a surprising twist. New satellite data and advanced simulations show that the morning side of the magnetosphere carries a negative charge, not positive as long believed. Researchers from Kyoto, Nagoya, and Kyushu Universities found that while the polar regions retain the expected polarity, the equatorial areas flip it entirely. Read more ›
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Disrupted sleep patterns in Alzheimer’s disease may be more than a symptom—they could be a driving force. Researchers at Washington University found that the brain’s circadian rhythms are thrown off in key cell types, changing when hundreds of genes turn on and off. This disruption, triggered by amyloid buildup, scrambles normal gene timing in microglia and astrocytes—cells vital for brain maintenance and immune defense. Read more ›
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Scientists have discovered that a “longevity gene” found in people who live beyond 100 can reverse heart aging in models of Progeria, a devastating disease that causes children to age rapidly. By introducing this supercentenarian gene into Progeria-affected cells and mice, researchers restored heart function, reduced tissue damage, and slowed aging symptoms. The discovery opens the door to new therapies inspired by the natural biology of long-lived humans—possibly reshaping how... Read more ›
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Beneath the ocean’s surface, bacteria have evolved specialized enzymes that can digest PET plastic, the material used in bottles and clothes. Researchers at KAUST discovered that a unique molecular signature distinguishes enzymes capable of efficiently breaking down plastic. Found in nearly 80% of ocean samples, these PETase variants show nature’s growing adaptation to human pollution. Read more ›
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After the collapse of the Chalcolithic culture around 3500 BCE, people in Jordan’s Murayghat transformed their way of life, shifting from domestic settlements to ritual landscapes filled with dolmens, standing stones, and megalithic monuments. Archaeologists from the University of Copenhagen believe these changes reflected a creative social response to climate and societal upheaval. Read more ›
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Cockroach infestations don’t just bring creepy crawlers, they fill homes with allergens and bacterial toxins that can trigger asthma and allergies. NC State researchers found that larger infestations meant higher toxin levels, especially from female roaches. When extermination eliminated the pests, both allergens and endotoxins plummeted. The findings highlight how pest control is vital for cleaner, healthier air indoors. Read more ›
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06.11.2025 07:35
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