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Researchers have finally seen and measured the tiny alpha-synuclein oligomers that may ignite Parkinson’s disease. With the ultra-sensitive ASA-PD imaging method, they captured these clusters in brain tissue, finding larger and more numerous versions in patients with Parkinson’s. The discovery could mark a turning point in diagnosing and treating the disease, revealing the first visible signs long before symptoms appear.
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ScienceDaily
Ontario's ad criticizing tariffs aired during the World Series, hours after President Donald Trump said he'd slap new tariffs on Canada. Read more ›
5,786 fresh
Google is listening to your feedback and making thinks smoother, one update at a time. Read more ›
925 fresh
Trump said he will increase tariffs on Canada by another 10% in response to a Canadian anti-tariff ad featuring former President Ronald Reagan. Read more ›
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A lawmaker demanded companies who donated to Trump's ballroom project release the size of the donations and if they were promised anything in return. Read more ›
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A few days ago, Honor unveiled the Magic8 and Magic8 Pro and earlier this week the pair of them went on sale in China. We have confirmation from Honor itself that the Magic8 series will also be available globally, though we don’t have the concrete details just yet. Would you buy the Magic8 or Magic8 Pro? The two new models boast the latest Snapdragon 8 Elite Gen 5 – another... Read more ›
360 fresh
We've lined up a selection of the best mirrorless cameras, including models from top brands like Canon and Sony. Read more ›
351 fresh
How to get free books on Stuff Your Kindle Day. Get Spooked, hosted by Indie Author Central, is offering paranormal, mystery, thriller, and horror books for free. Read more ›
180 fresh
A new study shows that eating more fruits and vegetables during the day can significantly improve sleep that same night. Researchers found a clear link between diet quality and sleep depth, with participants who met the CDC’s daily produce recommendations seeing a 16% boost in sleep quality. The findings suggest that small dietary changes could make a big difference in how well we rest. Read more ›
153 fresh
The new Chevrolet Bolt is cheaper than other "affordable" EVs, and even fixes the weaknesses of its predecessor. Read more ›
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Long-time Slashdot reader theodp took a good look at the images on a promotional web page for Databricks' "context-aware AI assistant": If there was an AI Demo Hall of Shame, the first inductee would have to be Amazon. Their demo tried to support its CEO's claims that Amazon Q Code Transformation AI saved it 4,500 developer-years and an additional $260 million in "annualized efficiency gains" by automatically and accurately upgrading... Read more ›
126 fresh
Bruce Springsteen met his future bandmate and wife, Patti Scialfa, at a New Jersey rock club in the '80s. Today, they share three children. Read more ›
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For the first time, scientists have seen a subduction zone actively breaking apart beneath the Pacific Northwest. Seismic data show the oceanic plate tearing into fragments, forming microplates in a slow, step-by-step collapse. This process, once only theorized, explains mysterious fossil plates found elsewhere and offers new clues about earthquake risks. The dying subduction zone is revealing Earth’s tectonic life cycle in real time. Read more ›
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Mealtime in my house was chaotic. Introducing new rules to follow each week helped my kids with table manners. Read more ›
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With more personal devices online than ever, upgrading to symmetrical internet speeds can make a bigger difference than you'd imagine. Read more ›
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Jess Lee, a Silicon Valley veteran, said there are four metrics she uses to evaluate people. No one is good at all of them, she said. Read more ›
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The Windows 10 end-of-support deadline is driving the largest coordinated PC replacement cycle in years across the industry, and Apple is emerging as one of the main beneficiaries as Mac shipments accelerate. Counterpoint Research this week reported that nearly 40% of the global installed PC base was still running Windows 10 ahead of the October 2025 cutoff, triggering early fleet renewals across both commercial and consumer channels. This pressure lifted... Read more ›
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Welcome to our latest roundup of what's going on in the indie game space. It's been a packed week with lots of tasty new games arriving, and news and reveals of upcoming projects. So, let's take a look at a bunch of them.Before we get started though, Engadget senior editor Jessica Conditt spoke with Maxi Boch, one of the core trio behind Baby Steps, about how the game came together.... Read more ›
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An AI system "apparently mistook a high school student's bag of Doritos for a firearm," reports the Guardian, "and called local police to tell them the pupil was armed." Taki Allen was sitting with friends on Monday night outside Kenwood high school in Baltimore and eating a snack when police officers with guns approached him. "At first, I didn't know where they were going until they started walking toward me... Read more ›
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2021 saw five times as many unruly passengers as the year before, and incidents have remained high. International rules classify them into four levels. Read more ›
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ScienceDaily
A groundbreaking study reveals that cancer patients who received a COVID-19 mRNA vaccine within 100 days of starting immunotherapy lived dramatically longer than those who didn’t. Researchers from the University of Florida and MD Anderson Cancer Center discovered that the vaccine’s immune-activating properties may boost cancer-fighting responses, acting like a nonspecific “flare” that reawakens the immune system. Read more ›
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Scientists have found a new way to stop cancer growth without damaging healthy cells. Researchers from the Francis Crick Institute and Vividion Therapeutics discovered a compound that blocks the signal telling cancer cells to grow and divide. The treatment worked in mice with lung and breast tumors and didn’t cause harmful side effects seen in earlier drugs. Now entering human trials, this breakthrough could open the door to safer, more... Read more ›
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MIT scientists have found that an amino acid called cysteine can help the gut heal itself. In mouse studies, a cysteine-rich diet activated immune cells that release a molecule speeding up tissue repair in the small intestine. This process helped regenerate the gut lining after damage from radiation or chemotherapy. Read more ›
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A new light-driven cancer therapy uses LEDs and tin nanoflakes to kill tumors safely and affordably. Developed by teams in Texas and Portugal, it eliminates up to 92% of skin cancer cells without harming healthy ones. Read more ›
119
Researchers have developed a DNA-based therapy that targets the PCSK9 gene to lower cholesterol naturally. Using polypurine hairpins, they increased cholesterol uptake by cells and reduced artery-clogging lipid levels. The results show dramatic drops in PCSK9 and cholesterol levels in animal models, pointing to a safer and more effective alternative to statins. Read more ›
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SuperAgers defy normal aging by keeping sharp memories and healthy brains well into their 80s. Northwestern scientists discovered that these individuals either resist the buildup of harmful brain proteins or remain unaffected by them. Their brains stay structurally youthful, and their strong social lives may help protect cognition. The findings could inspire new ways to delay or prevent dementia. Read more ›
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Scientists have uncovered a toxic alliance between Aβ and fibrinogen that may explain how Alzheimer’s disease begins. The two proteins together create stubborn clots that damage blood vessels and spark inflammation in the brain. These effects appear even at very low concentrations and disrupt the blood-brain barrier, paving the way for neurodegeneration. The findings highlight a potential new therapeutic target for early intervention. Read more ›
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A major collaboration between UC San Diego and 23andMe identified genes that shape cannabis use behaviors. The study linked the CADM2 and GRM3 genes to cannabis use and connected these patterns to more than 100 traits across mental and physical health. Researchers say understanding these genetic influences could help prevent cannabis use disorder and guide future therapies. Read more ›
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Researchers have finally seen and measured the tiny alpha-synuclein oligomers that may ignite Parkinson’s disease. With the ultra-sensitive ASA-PD imaging method, they captured these clusters in brain tissue, finding larger and more numerous versions in patients with Parkinson’s. The discovery could mark a turning point in diagnosing and treating the disease, revealing the first visible signs long before symptoms appear. Read more ›
54
A study found that daily vitamin D supplements helped slow telomere shortening—the cellular process linked to aging and disease. Researchers believe its anti-inflammatory effects may protect DNA. While results are promising, the ideal dose remains unclear, and experts stress that lifestyle choices still matter most for longevity. Read more ›
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Business Insider
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Gizmodo
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10% 5 |
Tom's Hardware
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9% 3 |
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7% 3 |
CNET
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6% 4 |
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26.10.2025 02:24
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