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A powerful new drug combination—niraparib added to standard prostate cancer therapy—has been shown to significantly delay disease progression in men with specific DNA repair gene mutations. In the large AMPLITUDE trial, patients receiving the combo lived longer without symptoms worsening and saw nearly a 50% risk reduction in BRCA-mutated cases. While side effects like anemia were more common, the results mark a major step toward precision medicine for prostate cancer.
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ScienceDaily
It's Valve time. The Bellevue-based firm is making three hardware announcements today, including a new Steam Machine mini PC that it claims is more than six times as powerful as the Steam Deck, a revised Steam Controller with more mainstream appeal, and the Steam Frame, a new standalone VR headset that marks the debut of SteamOS on ARM mobile chips. All three are due to arrive in early 2026. Read... Read more ›
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Valve has made a trio of hardware announcements today, including a standalone VR headset with unique tech for streaming games called Frame, a revised and more mainstream Steam Controller, and even a revival of the old Steam Machine concept: a tiny gaming PC that brings your Steam game library to your living room. Read more Read more ›
2,563 fresh
Treasury Secretary Bessent's comments came after President Donald Trump said he would lower some tariffs. Read more ›
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Valve is about to challenge the Xbox and PlayStation on their home turf. Ten years to the month after Valve's original Steam Machines went on sale, the company is announcing… the Steam Machine. I flew to Valve's headquarters to try the company's new PC-based game console, alongside a brand-new Steam Controller and the new Steam […] Read more ›
794 fresh
The government minted the final one-cent coin in Philadelphia, though billions remain in circulation. Read more ›
666 fresh
Pornhub and other studios formed the Adult Studio Alliance and released a safety standard for the adult industry. Read more ›
520 fresh
Nintendo has finally shown the first official trailer for The Super Mario Galaxy Movie, its follow-up to the phenomenally successful The Super Mario Bros. Movie. Read more Read more ›
481 fresh
The high-end grocery chain has operated separately from Amazon for years. That is about to change in dramatic ways. Read more ›
465 fresh
Anthropic believes AI models will increasingly reach into the physical world. To understand where things are headed, it asked Claude to program a quadruped. Read more ›
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Valve has unveiled a new Steam Machine console, taking a second shot at living room gaming a decade after its 2015 Steam Machine initiative failed. The 6-inch cube runs Linux-based SteamOS but plays Windows games through Proton, a compatibility layer built on Wine that translates Microsoft graphical APIs. Valve spent over a decade working on SteamOS and ways to run Windows games on Linux after the original Steam Machines failed.... Read more ›
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Sony has revealed the list of November additions to its PlayStation Plus Game Catalog for those on the Extra and Premium tiers of the subscription service. It’s a pretty darn good slate of games this time around, headlined by the return of the PS4 and PS5 versions of Grand Theft Auto V to the service. It’s at least the third time GTA V has been part of the Game Catalog... Read more ›
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Valve is taking another run at offering a console-style experience in your living room. The company has announced a new Steam Machine and Steam Controller that let you play PC games on your TV in the same way the Steam Deck lets you play them on the go.The Steam Machine works like a console, but is technically a compact PC. The boxy device features a customizable front plate and LED... Read more ›
396 fresh
Riders in San Francisco, Phoenix, and Los Angeles will soon be able to take freeway rides. Read more ›
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SteamOS-powered cube for your TV targets early 2026 launch, no pricing details. Read more ›
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Verizon Home Internet Lite delivers affordable service, but it comes with a few downsides. Read more ›
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On the 15th floor of an upscale office building in Bellevue, Washington, security guards line the halls. They're here to make sure we don't stray - because I'm visiting Valve's headquarters, a place few journalists ever get to go. The guards help escort me to a tiny demo room, where a pair of Valve engineers […] Read more ›
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ScienceDaily
Prenatal exposure to the insecticide chlorpyrifos causes widespread brain abnormalities and poorer motor skills in children. Even after a residential ban, ongoing agricultural use continues to endanger developing brains. Read more ›
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Researchers in Osaka have found that stem cells from fat tissue can repair spinal fractures similar to those caused by osteoporosis. By turning these cells into bone-forming clusters and pairing them with a bone-rebuilding material, rats regained stronger, healthier spines. The approach could offer a safe, minimally invasive alternative for treating bone diseases in humans. Read more ›
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Intermountain Health researchers discovered that customizing vitamin D3 doses for heart attack survivors slashed their risk of another heart attack by 50%. The strategy involved frequent monitoring and dose adjustments to reach ideal vitamin D levels. Traditional studies didn’t track blood levels, missing this critical link. Read more ›
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Researchers have identified special immune cells in the brain that help slow Alzheimer’s. These microglia work to reduce inflammation and block the spread of harmful proteins. They appear to protect memory and brain health, offering a promising new direction for therapy. Read more ›
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Aalto University scientists have created a laser-based treatment that uses gentle heat to stop the progression of dry macular degeneration. The approach stimulates the eye’s natural cleanup and repair systems to protect against blindness. Read more ›
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A new theory claims dark matter and dark energy don’t exist — they’re just side effects of the universe’s changing forces. By rethinking gravity and cosmic timelines, it could rewrite our understanding of space and time itself. Read more ›
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New research finds that daily coffee drinking may cut AFib risk by nearly 40%, defying decades of medical caution. Scientists discovered that caffeine’s effects on activity, blood pressure, and inflammation could all contribute to a healthier heart rhythm. The DECAF clinical trial’s findings suggest coffee could be not only safe but beneficial for people with A-Fib. Read more ›
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Researchers have discovered that prostate cancer depends on two key enzymes, PDIA1 and PDIA5, to survive and resist therapy. When blocked, these enzymes cause the androgen receptor to collapse, killing cancer cells and enhancing the effects of drugs like enzalutamide. They also disrupt the cancer’s energy system, striking it on multiple fronts. This breakthrough could open a new path to overcoming drug resistance in advanced prostate cancer. Read more ›
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Japanese researchers found that lecanemab, an amyloid-clearing drug for Alzheimer’s, does not improve the brain’s waste clearance system in the short term. This implies that nerve damage and impaired clearance occur early and are difficult to reverse. Their findings underscore that tackling amyloid alone may not be enough to restore brain function, urging a broader approach to treatment. Read more ›
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An extract from a desert berry used in traditional Chinese medicine restored insulin function and stabilized metabolism in diabetic mice. The findings hint at a powerful natural alternative for holistic diabetes treatment. Read more ›
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Business Insider
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22% 3 |
Eurogamer.net
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15% 12 |
Gizmodo
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9% 0 |
Tom's Hardware
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6% 0 |
Android Authority
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6% 1 |
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12.11.2025 17:21
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