79 place 18
Scientists at UC San Diego have identified a new drug, ION224, that could transform the treatment of MASH, a dangerous form of fatty liver disease tied to obesity and diabetes. By blocking a key liver enzyme, the drug reduces fat and inflammation, halting the root causes of liver damage. In a year-long clinical trial, patients showed major improvements without serious side effects, offering hope to millions affected worldwide.
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ScienceDaily
Crews aboard the USCGC Stone offloaded a record-breaking amount of cocaine on Wednesday after 15 drug interdictions in the eastern Pacific. Read more ›
1,028 fresh
Disney+ has Star Wars and Paramount+ has Star Trek, so it's about time Amazon gets its own sci-fi franchise with "star" in the title. Prime Video has just greenlit a TV revival of the iconic Stargate franchise, according to a report by Deadline. This will be the fourth major TV show in the series, following the first movie. We don't know anything about the plot and where it fits into... Read more ›
734 fresh
Nvidia's modular PCIe connector, used in some of its Blackwell-based graphics cards, is available individually. Read more ›
726 fresh
Warner Music Group (WMG) settled a lawsuit with an AI company in exchange for a piece of the action. The label announced on Wednesday that it had resolved a 2024 lawsuit against AI music creation platform Udio. As part of the deal, Udio gets to license Warner's catalog for an upcoming music creation service. This follows a similar settlement between Universal Music Group and Udio, announced last month.Udio's service will... Read more ›
535 fresh
The company that wants you to #optoutside for Black Friday is having its sale early. Gear up for next year with these great deals on packs, sleeping bags, merino wool, and more. Read more ›
511 fresh
We found early Black Friday deals on WIRED-tested smart bird feeders, smartwatches, vacuums, and more. Read more ›
494 fresh
Microsoft is preventing hilarity from ensuing by adding a new Digital Signage Mode in Windows 11. This recovery feature will force a BSOD or any error pop-up to disappear within 15 seconds so that the public can't enjoy the mundanity of life. Digital Signage Mode is different from the existing Kiosk mode for interactive screens. Read more ›
450 fresh
This is just a little public service announcement ahead of Black Friday. Walmart will once again tout the M1 MacBook Air as an unbeatable deal for laptop shoppers. It sure is tempting at $599, especially if you haven’t seen the deal before. It might even be the right choice for some people. But for most […] Read more ›
419 fresh
Agreement with Udio could allow fans to create their own songs using licensed tracks if artists opt in Read more ›
364 fresh
Barclays analysts did a deep dive into OpenAI's growth and expansion prospects. Their findings suggest more support for AI infrastructure spending. Read more ›
350 fresh
The spectrum licenses from EchoStar significantly increase the 5G capacity for AT&T subscribers. Read more ›
347 fresh
Donald Trump has spent years benefiting from the QAnon's Jeffrey Epstein obsession. That’s all changing. Read more ›
319 fresh
Linus Torvalds is "fairly positive" about vibe coding as a way for people to get computers to do things they otherwise could not. The Linux kernel maintainer made the comments during an interview at the Linux Foundation Open Source Summit in Seoul earlier this month. But he cautioned that vibe coding would be a "horrible, horrible idea from a maintenance standpoint" for production code. Torvalds told Dirk Hohndel, head of... Read more ›
318 fresh
The aging pair of stars swing by one another once every 190 years, producing four spirals of dust. Read more ›
299 fresh
The EU's cookie consent policies have been an annoying and unavoidable part of browsing the web in Europe since their introduction in 2018. But the cookie nightmare is about to crumble thanks to some big proposed changes announced by the European Commission today. From a report: Instead of having to click accept or reject on a cookie pop-up for every website you visit in Europe, the EU is preparing to... Read more ›
297 fresh
The most shocking thing about President Donald Trump’s Oval Office meeting with Saudi Crown Prince Mohammed Bin Salman on Tuesday was that anyone was shocked by it. The main headline coming out of the two leaders’ combative session with reporters was Trump’s blasé dismissal of a question about the 2018 murder of Washington Post columnist […] Read more ›
287 fresh
Yann LeCun, the artificial intelligence pioneer and Meta Platform’s chief AI scientist, plans to leave the company at the end of the year to form his own AI startup, according to a person with direct knowledge of his plans. A Meta spokesperson confirmed LeCun’s departure and said the company plans to partner with LeCun’s startup. This story is developing Read more ›
281 fresh
ScienceDaily
Researchers found that tau proteins don’t jump straight into forming Alzheimer’s-associated fibrils—first they assemble into soft, reversible clusters. When the clusters were dissolved, fibril growth was almost entirely suppressed. This reveals a promising new strategy: stop the precursors, stop the disease. Read more ›
162
Rutgers scientists found that metformin can blunt many of the metabolic and cardiovascular improvements normally produced by exercise. Participants who took the drug saw reduced gains in fitness, blood vessel function, and glucose control. The interference may stem from how metformin affects mitochondrial activity. Read more ›
137
Older adults who regularly listen to or play music appear to have significantly lower risks of dementia and cognitive decline. The data suggests that musical engagement could be a powerful, enjoyable tool for supporting cognitive resilience in aging. Read more ›
134
Researchers uncovered how fatty molecules called ceramides trigger acute kidney injury by damaging the mitochondria that power kidney cells. By altering ceramide metabolism or using a new drug candidate, the team was able to protect mitochondrial function and completely prevent kidney injury in mice. Read more ›
110
Chronic kidney disease has surged to nearly 800 million cases and is now among the top causes of death worldwide. The condition is heavily linked to diabetes, hypertension, and obesity, and often goes unnoticed until late stages. Many countries lack access to dialysis and transplants, leaving millions without adequate care. Read more ›
103
Exercise appears to spark a whole-body anti-aging cascade, and scientists have now mapped out how it happens—and how a simple oral compound can mimic it. By following volunteers through rest, intense workouts, and endurance training, researchers found that the kidneys act as the hidden command center, flooding the body with a metabolite called betaine that restores balance, rejuvenates immune cells, and cools inflammation. Even more striking, giving betaine on its... Read more ›
100
Researchers have designed a smart drug that hunts down and breaks a little-known RNA that cancer cells depend on. The drug recognizes a unique fold in the RNA and triggers the cell to destroy it. Tests showed that removing this RNA slows cancer growth. The approach could lead to new treatments that attack cancer at its most fundamental level. Read more ›
72
Electrons can freeze into strange geometric crystals and then melt back into liquid-like motion under the right quantum conditions. Researchers identified how to tune these transitions and even discovered a bizarre “pinball” state where some electrons stay locked in place while others dart around freely. Their simulations help explain how these phases form and how they might be harnessed for advanced quantum technologies. Read more ›
51
Scientists discovered that alcohol activates a sugar-producing pathway in the body, creating fructose that may reinforce addictive drinking. The enzyme responsible, KHK, appears to drive both alcohol cravings and liver injury. When this enzyme was blocked in mice, their drinking decreased and their livers showed far less damage. Read more ›
46
Scientists found that people who use both cannabis and tobacco show a distinct brain pattern tied to mood and stress regulation. Their scans revealed higher levels of an enzyme that reduces a natural feel-good molecule in the brain. This imbalance may help explain why co-users experience more anxiety and struggle more when quitting. Read more ›
39
Most popular sources
Business Insider
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25% 9 |
Tom's Hardware
|
10% 11 |
Gizmodo
|
7% 4 |
The Verge
|
7% 3 |
Engadget
|
6% 2 |
| View sources » | |
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19.11.2025 17:37
Last update: 17:30 EDT.
News rating updated: 00:33.
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