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Scientists at UC San Diego have identified a new drug, ION224, that could transform the treatment of MASH, a dangerous form of fatty liver disease tied to obesity and diabetes. By blocking a key liver enzyme, the drug reduces fat and inflammation, halting the root causes of liver damage. In a year-long clinical trial, patients showed major improvements without serious side effects, offering hope to millions affected worldwide.
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Samsung has offered orange colors before, but this vibrant shade would be more in line with Apple's latest wares. Read more ›
889 fresh
Swift said she had respect for people's subjective opinions on art, and she was "not the art police." Read more ›
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"There are people that are living in a MAGA universe online," Ocasio-Cortez said. "And that happens as well in progressive content and algorithms." Read more ›
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Tariffs. United States Immigration and Customs Enforcement raids. National Guard deployments. Epstein files. Strikes on Iran. Gaza and Ukraine. Sticky inflation. The first year of President Donald Trump’s time in office has been a firehose of unpopular policies, confrontational tactics, and frequent clashes with his perceived enemies. Each of these developments has tended to trigger […] Read more ›
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Companies struggle to assess scale of financial risks emerging from artificial intelligence Read more ›
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Major airports like Nashville, Chicago O'Hare, and Dallas-Fort Worth are all facing significant delays. Read more ›
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The White House says furloughed federal workers aren't automatically entitled to back pay, and Congress may have to pass a law to grant it to them. Read more ›
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NBC is developing a game show based on the New York Times' Wordle puzzle, with Today anchor Savannah Guthrie set to host and Jimmy Fallon executive producing through his company, Electric Hot Dog. The Times is also a production partner. From the Hollywood Reporter: Wordle, which the Times acquired in 2022 and logs billions of plays from the paper's games site annually, gives players six tries to guess a five-letter... Read more ›
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A single mom with Stage 5 cancer was told by doctors that she had a few months to live. Hosting a 'living funeral' helped her face her own death. Read more ›
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Analysts and business leaders had mixed reactions to Tesla's new, more affordable models, which are about $5,000 cheaper. Read more ›
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I've changed the way I talk to my teens when I need to confront them about something they probably won't like. It's made a huge difference. Read more ›
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Venture capital funds close to raising $1.1bn this year in first signs of thaw for sector hit by geopolitical tensions Read more ›
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"I'm definitely not buying them. For the same price, there are far more options I can get from local automakers," one user wrote on Weibo. Read more ›
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New $37,990 ‘standard’ version is 15% less expensive than the previous base offering Read more ›
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If you have small devices that are on the fritz — or in need of a slight modification — Hoto’s Electric Precision Screwdriver ADV is great for DIY projects. Its size and power make it well-suited for tinkering with phones, laptops, and handheld gaming consoles, with its pen-style grip, simple one-button operation, and a tidy […] Read more ›
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Apple is currently beta testing iOS 26.1, which will be the first major update to the iOS 26 operating system. It's not going to bring the new version of Siri that we've been waiting for, but it does include useful new features and interface changes. We've rounded up all of the features that have been in iOS 26.1 so far. Alarms and Timers Alarms and timers that you set up... Read more ›
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Connections: Sports Edition is a New York Times word game about finding common sports threads between words. How to solve the day's puzzle. Read more ›
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Travellers across the US faced flight delays on Monday due to air traffic controller staffing shortages during the government shutdown. Read more ›
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Apple today provided public beta testers with the second releases of upcoming iOS 26.1, iPadOS 26.1, macOS Tahoe 26.1, tvOS 26.1 and watchOS 26.1 updates for testing purposes. Apple seeded the betas to developers yesterday. After signing up for beta testing on Apple's beta site, public beta testers can download the updates using the Software Update section in the Settings app on each device. iOS 26.1, iPadOS 26.1, and macOS... Read more ›
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Addiction often isn’t about chasing pleasure—it’s about escaping pain. Researchers at Scripps Research have discovered that a tiny brain region called the paraventricular nucleus of the thalamus (PVT) becomes hyperactive when animals learn that alcohol eases the agony of withdrawal. This circuit helps explain why people relapse: their brains learn that alcohol brings relief from stress and anxiety. Read more ›
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Zeaxanthin, best known for eye health, has been found to boost the tumor-killing power of T cells. Researchers showed it strengthens T-cell receptors, enhances immune signaling, and improves the effects of immunotherapy. Found naturally in foods like spinach and peppers, it’s safe, accessible, and now a promising candidate for cancer treatment trials. Read more ›
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Scientists confirmed that pianists can alter timbre through touch, using advanced sensors to capture micro-movements that shape sound perception. The discovery bridges art and science, promising applications in music education, neuroscience, and beyond. Read more ›
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Ohio State researchers have discovered that exhausted T cells collapse under the weight of misfolded proteins, activating a destructive stress response called TexPSR. Unlike normal stress systems, TexPSR accelerates protein production, flooding the cells with toxic buildup. Blocking it restored T-cell function and improved cancer immunotherapy. Read more ›
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When cancer cells are physically squeezed, they mount an instant, high-energy defense by rushing mitochondria to the cell nucleus, unleashing a surge of ATP that fuels DNA repair and survival. This newly discovered mechanism, visualized in real time with advanced microscopy, shows mitochondria acting like emergency first responders rather than static power plants. The structures, called NAMs, were also identified in patient tumor biopsies, suggesting real-world relevance to cancer’s spread. Read more ›
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Flu detection could soon be as simple as chewing gum. Scientists have created a molecular sensor that releases a thyme-like flavor when it encounters influenza, offering a low-tech, taste-based alternative to nasal swabs. Unlike current tests that are slow, costly, or miss early infections, this method could catch the flu before symptoms appear. Read more ›
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New research reveals that deep-sea mining could dramatically threaten 30 species of sharks, rays, and ghost sharks whose habitats overlap with proposed mining zones. Many of these species, already at risk of extinction, could face increased dangers from seafloor disruptions and sediment plumes caused by mining activity. Read more ›
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A Penn State research team found that streetlights could double as affordable EV charging stations. After installing 23 units in Kansas City, they discovered these chargers were faster, cheaper, and more eco-friendly than traditional stations. Their AI-based framework also prioritized equity and scalability, making it adaptable for cities across the country. Read more ›
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Scientists discovered that vitamin D2 supplements can lower levels of vitamin D3, the form the body uses most effectively. Unlike D2, vitamin D3 enhances the immune system’s first line of defense against infections. This raises questions about which type of supplement should be prioritized. Read more ›
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Scientists have discovered that DMT, a natural compound found in plants and even the human brain, can dramatically reduce brain damage caused by stroke. The psychoactive molecule, long known for its hallucinogenic effects, restored the blood-brain barrier and reduced inflammation in animal and cell studies. These findings suggest that DMT could complement existing stroke treatments, potentially transforming recovery outcomes. Read more ›
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08.10.2025 04:21
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