Axi-cel CAR T targets the CD19 molecule on large B-cell lymphoma cells. The ZUMA-7 trial demonstrated that axi-cel reduced the risk of disease progression, the need for new therapy, or death by 60% compared to standard therapy. Despite these positive outcomes in event-free survival and overall survival, some patients did not respond well to therapy or relapsed quickly after treatment. Researchers wanted to assess if there were specific tumor characteristics... Read more ›
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Scientists have shown that people are able to tell apart morning from evening depictions in paintings using simple and subtle color clues in the image. Read more ›
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A 10-month mission demonstrated three elements of the plan to beam solar power from space to Earth. Read more ›
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New algorithms close the gap in deepfake detectors' accuracy across races and genders. Read more ›
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A combination of cognitive and behavioral strategies, ideally delivered in person by a therapist, maximizes the benefits of cognitive behavioral therapy for insomnia (CBT-I), according to new research. CBT-I is a form of talk therapy, which can be delivered in person or through self-help guides. By analyzing 241 studies, involving over 30,000 adults, researchers identified the most beneficial components of CBT-I. Read more ›
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Like Indiana Jones, thresher sharks have mastered the art of the whip using their tails. Now, new research provides intricate details showing that vertebrae anatomy might support the mechanics of extreme body bending in thresher sharks, enabling these expert hunters to weaponize their tails. Using micro-CT scanning similar to CAT scans in humans, and two-dimensional shape analysis, results of the study suggest vertebral anatomy and mineralized microstructure meet the demands... Read more ›
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Scientists have made an insight into superlubricity, where surfaces experience extremely low levels of friction. This could benefit future technologies by reducing energy lost to friction by moving parts. Read more ›
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Scientists have successfully demonstrated new technologies that can obtain preserved tissue and high-resolution 3D images within minutes of encountering some of the most fragile animals in the deep ocean. Read more ›
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Researchers have linked the travels of a 14,000-year-old woolly mammoth with the oldest known human settlements in Alaska, providing clues about the relationship between the iconic species and some of the earliest people to travel across the Bering Land Bridge. Isotopic data, along with DNA from other mammoths at the site and archaeological evidence, indicates that early Alaskans likely structured their settlements to overlap with areas where mammoths congregated. Those... Read more ›
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Having more women in agriculture is associated with greater community well-being, according to researchers. Their work suggests that women farmers approach their operations in ways that positively impact their communities. Read more ›
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Just like a book can't be judged by its cover, a material can't always be judged by its surface. But, for an elusive conjectured class of materials, physicists have now shown that the surface previously thought to be 'featureless' holds an unmistakable signature that could lead to the first definitive observation. Read more ›
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Researchers report the development of a methodology to detect small amounts of potential tumor therapeutic targets, specificacally enzymes called kinases, that are present in biopsy samples. Therapies that directly inhibit cancer-promoting activities of some of these kinases have proven to be effective for patients in which individual driving kinases can be diagnosed. Read more ›
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A mouse study designed to shed light on memory loss in people who experience repeated head impacts, such as athletes, suggests the condition could potentially be reversed. The research in mice finds that amnesia and poor memory following head injury is due to inadequate reactivation of neurons involved in forming memories. Read more ›
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This month, a group of stroke survivors in British Columbia will test a new technology designed to aid their recovery, and ultimately restore use of their limbs and hands. Participants will wear a new groundbreaking 'smart glove' capable of tracking their hand and finger movements during rehabilitation exercises. Read more ›
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Fossils of kelp along the Pacific Coast are rare. Until now, the oldest fossil dated from 14 million years ago, leading to the view that today's denizens of the kelp forest -- marine mammals, urchins, sea birds -- coevolved with kelp. A recent amateur discovery pushes back the origin of kelp to 32 million years ago, long before these creatures appeared. A new analysis suggests the first kelp grazers were... Read more ›
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Climate change is causing Western U.S. forests to be less effective carbon sinks, even as it boosts the productivity of forests in the Eastern U.S., according to new research. Read more ›
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'Soft robots,' medical devices and implants, and next-generation drug delivery methods could soon be guided with magnetism -- thanks to a metal-free magnetic gel developed by researchers. Carbon-based, magnetic molecules are chemically bonded to the molecular network of a gel, creating a flexible, long-lived magnet for soft robotics. Read more ›
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Supersulfides, many of which are produced by cysteinyl-tRNA synthetase (CARS), are essential compounds across many different lifeforms. However, the precise physiological roles of CARS-produced supersulfide are unclear. Now, using a strategically engineered yeast mutant with a deficient CARS gene, researchers from Japan have shown that supersulfides control cell longevity by mediating mitochondrial energy metabolism and regulating protein quality. Read more ›
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The use of the antipsychotic drugs quetiapine and haloperidol is associated with an increased risk of ventricular arrhythmias and sudden cardiac death (SCD) caused by drug-induced QT prolongation, reports a new study. Caution is advised to manage cardiac risks in patients prescribed these medications, the authors of the study and an accompanying editorial say. Read more ›
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The Arctic, Earth's icy crown, is experiencing a climate crisis like no other. It's heating up at a furious pace -- four times faster than the rest of our planet. Researchers are pulling back the curtain on the reduction of sunlight reflectivity, or albedo, which is supercharging the Arctic's warming. Read more ›
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24.07.2026 15:47
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