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ScienceDaily 2 place · 03/27/2024 15:49 EDT

Combining epigenetic cancer medications may have benefit for colorectal cancers and other tumor types

A pair of medications that make malignant cells act as if they have a virus could hold new promise for treating colorectal cancers and other solid tumors, reports a new study. The preclinical research determined how low doses of a DNMT inhibitor sensitize cancer cells to an EZH2 inhibitor, resulting in a one-two punch that combats cancer cells better than either drug alone. The findings are the foundation for an... Read more ›

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ScienceDaily
ScienceDaily · 03/27/2024 15:48 EDT

Land under water: What causes extreme flooding?

If rivers overflow their banks, the consequences can be devastating -- just like the catastrophic floods in North Rhine-Westphalia and Rhineland-Palatinate of 2021 showed. In order to limit flood damage and optimize flood risk assessment, we need to better understand what factors can lead to extreme forms of flooding and to what extent. Using methods of explainable machine learning, researchers have shown that floods are more extreme when several factors... Read more ›

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ScienceDaily
ScienceDaily · 03/27/2024 15:48 EDT

Robot, can you say 'cheese'?

What would you do if you walked up to a robot with a human-like head and it smiled at you first? You'd likely smile back and perhaps feel the two of you were genuinely interacting. But how does a robot know how to do this? Or a better question, how does it know to get you to smile back? Read more ›

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ScienceDaily
ScienceDaily · 03/27/2024 12:48 EDT

More efficient TVs, screens and lighting

New multidisciplinary research could lead to more efficient televisions, computer screens and lighting. Read more ›

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ScienceDaily
ScienceDaily · 03/27/2024 12:48 EDT

Sweet success: Sugarcane's complex genetic code cracked

Scientists created a highly accurate reference genome for one of the most important modern crops and found a rare example of how genes confer disease resistance in plants. Exploring sugarcane's genetic code could help researchers develop more resilient and productive crops, with implications for both sugar production and biofuels. Read more ›

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ScienceDaily
ScienceDaily · 03/27/2024 12:48 EDT

Making long-term memories requires nerve-cell damage

Just as you can't make an omelet without breaking eggs, scientists have found that you can't make long-term memories without DNA damage and brain inflammation. Read more ›

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ScienceDaily
ScienceDaily · 03/27/2024 12:48 EDT

Researchers turn back the clock on cancer cells to offer new treatment paradigm

Scientists reversed an aggressive cancer, reverting malignant cells towards a more normal state. Rhabdoid tumors are an aggressive cancer which is missing a key tumor suppressor protein. Scientists discovered that removing a second protein from cancer cells already experiencing tumor suppressor loss can reverse cancer cell identity. Read more ›

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ScienceDaily
ScienceDaily · 03/27/2024 12:47 EDT

Want to feel young? Protect your sleep

Do you ever find yourself longing for the energy and vitality of your younger years? Feeling young is not just a matter of perception it is actually related to objective health outcomes. Previous studies have shown that feeling younger than one s actual age is associated with longer, healthier lives. There is even support for subjective age to predict actual brain age, with those feeling younger having younger brains. Feeling... Read more ›

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ScienceDaily
ScienceDaily · 03/27/2024 12:47 EDT

Scientists extract genetic secrets from 4,000-year-old teeth to illuminate the impact of changing human diets over the centuries

Researchers have recovered remarkably preserved microbiomes from two teeth dating back 4,000 years, found in an Irish limestone cave. Genetic analyses of these microbiomes reveal major changes in the oral microenvironment from the Bronze Age to today. The teeth both belonged to the same male individual and also provided a snapshot of his oral health. Read more ›

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ScienceDaily
ScienceDaily · 03/27/2024 12:47 EDT

Social, environmental factors may raise risk of developing heart disease and stroke

Neighborhoods with more adversity have up to twice the increased risk of heart disease and stroke, according to a new study. Read more ›

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ScienceDaily
ScienceDaily · 03/27/2024 12:47 EDT

A tiny spot leads to a large advancement in nano-processing, researchers reveal

Focusing a tailored laser beam through transparent glass can create a tiny spot inside the material. Researchers have reported on a way to use this small spot to improve laser material processing, boosting processing resolution. Read more ›

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ScienceDaily
ScienceDaily · 03/27/2024 12:47 EDT

Scientists warn: The grey seal hunt is too large

Researchers warn that today's hunting quotas of about 3,000 animals pose a risk to the long-term survival of the grey seal in the Baltic Sea. The conclusions of this new study are based on statistics from 20th century seal hunting and predictions of future climate change. Read more ›

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ScienceDaily
ScienceDaily · 03/27/2024 12:47 EDT

Spot-on laser treatment for skin blemishes becoming clearer with new index

Scientists have developed the first wavelength-specific irradiation index for picosecond lasers, which are used in clinical practice to treat pigmented lesions. Comparison with previously reported clinical studies confirmed that clinical results showing low complication rates and high efficacy can be explained by the indicator they developed. The use of this indicator is expected to help set irradiation conditions in clinical practice. Read more ›

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ScienceDaily
ScienceDaily · 03/27/2024 12:47 EDT

Rock-wallaby bite size ‘packs a punch’

Australian rock-wallabies are 'little Napoleons' when it comes to compensating for small size, packing much more punch into their bite than larger relatives. Researchers made the discovery while investigating how two dwarf species of rock-wallaby are able to feed themselves on the same kinds of foods as their much larger cousins. Read more ›

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ScienceDaily
ScienceDaily · 03/27/2024 12:47 EDT

A solar cell you can bend and soak in water

Researchers have developed an organic photovoltaic film that is both waterproof and flexible, allowing a solar cell to be put onto clothes and still function correctly after being rained on or even washed. Read more ›

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ScienceDaily
ScienceDaily · 03/27/2024 12:47 EDT

Getting too little sleep linked to high blood pressure

Sleeping fewer than seven hours is associated with a higher risk of developing high blood pressure over time, according to a new study. Read more ›

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ScienceDaily
ScienceDaily 1 place · 03/27/2024 12:47 EDT

Risk factors for faster aging in the brain revealed in new study

Researchers have used data from UK Biobank participants to reveal that diabetes, traffic-related air pollution and alcohol intake are the most harmful out of 15 modifiable risk factors for dementia. Read more ›

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ScienceDaily
ScienceDaily · 03/27/2024 12:47 EDT

New technique for predicting protein dynamics may prove big breakthrough for drug discovery

Understanding the structure of proteins is critical for demystifying their functions and developing drugs that target them. To that end, a team of researchers has developed a way of using machine learning to rapidly predict multiple protein configurations to advance understanding of protein dynamics and functions. Read more ›

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ScienceDaily
ScienceDaily · 03/27/2024 12:47 EDT

Secrets of the naked mole-rat: new study reveals how their unique metabolism protects them from heart attacks

This unusual, subterranean mammal with extreme longevity shows genetic adaptations to low oxygen environments which could offer opportunities for advancing other areas of physiological and medical research in humans, including the development of novel therapeutic approaches. Read more ›

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