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ScienceDaily · 04/12/2024 11:34 EDT

Innovative antiviral defense with new CRISPR tool

The rise of RNA viruses like SARS-CoV-2 highlights the need for new ways to fight them. RNA-targeting tools like CRISPR/Cas13 are powerful but inefficient in the cytoplasm of cells, where many RNA viruses replicate. Scientists have devised a solution: Cas13d-NCS. This new molecular tool allows CRISPR RNA molecules that are located within the nucleus of a cell to move to the cytoplasm, making it highly effective at neutralizing RNA viruses.... Read more ›

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ScienceDaily
ScienceDaily · 04/12/2024 11:34 EDT

Iconic savanna mammals face genetic problems due to fences and roads

Wildebeest migrations have become a rarer sight in Africa as humans continue to interrupt their historic migratory routes with roads, fences, cities, livestock and farmland. This has led to genetic decay in those herds that are no longer able to roam freely, according to new research. Read more ›

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ScienceDaily
ScienceDaily 2 place · 04/12/2024 11:34 EDT

Brightest gamma-ray burst of all time came from the collapse of a massive star

In 2022, astronomers discovered the brightest gamma-ray burst (GRB) of all time. Now, astronomers confirm that a 'normal' supernova, the telltale sign of a stellar collapse, accompanied the GRB. The team also looked for signatures of heavy elements like gold and platinum in the supernova. They found no evidence of such elements, deepening the mystery of their origins. Read more ›

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ScienceDaily
ScienceDaily · 04/12/2024 11:34 EDT

Inherited predisposition for higher muscle strength may protect against common morbidities

A study showed that a genetic predisposition for higher muscle strength predicts a longer lifespan and a lower risk for developing common diseases. This is a highly comprehensive international study on hereditary muscle strength and its relationship to morbidity. The genome and health data of more than 340,000 Finns was used in the research. Read more ›

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ScienceDaily
ScienceDaily 1 place · 04/12/2024 11:34 EDT

Scientists uncover a missing link between poor diet and higher cancer risk

A research team has unearthed new findings which may help explain the connection between cancer risk and poor diet, as well as common diseases like diabetes, which arise from poor diet. The insights gained from this study hold promise for advancing cancer prevention strategies aimed at promoting healthy aging. Read more ›

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ScienceDaily
ScienceDaily · 04/12/2024 11:33 EDT

PFAS exposure from high seafood diets may be underestimated

A study suggests that people with diets high in seafood may face a greater risk of exposure to PFAS -- the family of human-made toxins known as 'forever chemicals' -- than previously thought. The researchers stress the need for more stringent public health guidelines that establish how much seafood people can safely consume to limit their exposure, particularly in coastal areas where seafood is frequently eaten. Read more ›

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ScienceDaily
ScienceDaily 3 place · 04/12/2024 11:33 EDT

Exoplanets true to size

A star's magnetic field must be considered in order to correctly determine the characteristics of exoplanets from observations by space telescopes such as Kepler, James Webb, or PLATO. Researchers show that the distribution of the star's brightness over its disk depends on the star's level of magnetic activity. This, in turn, affects the signature of an exoplanet in observational data. The new model must be used in order to properly... Read more ›

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ScienceDaily
ScienceDaily · 04/12/2024 11:31 EDT

Choosing sugary drinks over fruit juice for toddlers linked to risk of adult obesity

Consuming sugar-sweetened drinks in the first few years of childhood can be linked to poor diet patterns that increase the risk of obesity in later life, according to a new study. Read more ›

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ScienceDaily
ScienceDaily · 04/12/2024 11:30 EDT

Africa's iconic flamingos threatened by rising lake levels

It is one of the world's most spectacular sights -- huge flocks or 'flamboyances' of flamingos around East Africa's lakes -- as seen in the film Out of Africa or David Attenborough's A Perfect Planet. But new research has revealed how the lesser flamingo is at danger of being flushed out of its historic feeding grounds, with serious consequences for the future of the species. Read more ›

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ScienceDaily
ScienceDaily · 04/12/2024 11:30 EDT

Melanomas resist drugs by 'breaking' genes

A study has disentangled the mechanisms behind one of the ways melanoma cancer cells develop resistance to treatment. The study found that, in response to some drugs, melanomas can 'break' parts of their BRAF gene, which is mutated in 1 in 2 melanomas. This helps the tumor create alternative versions of the protein which lack regions targeted by one BRAF inhibitors, one of the main drugs used to treat this... Read more ›

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ScienceDaily
ScienceDaily · 04/11/2024 21:27 EDT

Two key brain systems are central to psychosis

When the brain has trouble filtering incoming information and predicting what's likely to happen, psychosis can result, research shows. Read more ›

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ScienceDaily
ScienceDaily · 04/11/2024 21:27 EDT

Cells putting on a face

Neural crest cells -- embryonic pluripotent cells within the facial primordium -- may be necessary for forming proper animal facial structures. Researchers have produced neural crest cell-rich aggregates from human pluripotent stem cells and developed a method to differentiate them in cell populations with a branchial arch-like gene expression pattern. Read more ›

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ScienceDaily
ScienceDaily · 04/11/2024 16:59 EDT

Artificial intelligence can help people feel heard

New research reveals AI-generated responses can make humans 'feel heard' but an underlying bias toward AI devalues its effectiveness. Read more ›

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ScienceDaily
ScienceDaily · 04/11/2024 16:59 EDT

Scientists use wearable technology to detect stress levels during sleep

What if changes in a person's stress levels could be detected while they sleep using wearable devices? A new study find changes in perceived stress levels reflected in sleep data -- an important step towards identifying biomarkers that may help flag individuals in need of support. Read more ›

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ScienceDaily
ScienceDaily · 04/11/2024 16:59 EDT

Beautiful nebula, violent history: Clash of stars solves stellar mystery

When astronomers looked at a stellar pair at the heart of a stunning cloud of gas and dust, they were in for a surprise. Star pairs are typically very similar, like twins, but in HD 148937, one star appears younger and, unlike the other, is magnetic. New data suggest there were originally three stars in the system, until two of them clashed and merged. This violent event created the surrounding... Read more ›

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ScienceDaily
ScienceDaily · 04/11/2024 16:59 EDT

Researchers identify new genetic risk factors for persistent HPV infections

Human papillomavirus (HPV) is the second most common cancer-causing virus, accounting for 690,000 cervical and other cancers each year worldwide. While the immune system usually clears HPV infections, those that persist can lead to cancer, and a new finding suggests that certain women may have a genetic susceptibility for persistent or frequent HPV infections. These genetic variants could raise a woman's risk of getting cervical cancer from a high-risk HPV... Read more ›

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ScienceDaily
ScienceDaily 3 place · 04/11/2024 16:59 EDT

First step to untangle DNA: Supercoiled DNA captures gyrase like a lasso ropes cattle

Researchers reveal how DNA gyrase resolves DNA entanglements. The findings not only provide novel insights into this fundamental biological mechanism but also have potential practical applications. Gyrases are biomedical targets for the treatment of bacterial infections and the similar human versions of the enzymes are targets for many anti-cancer drugs. Better understanding of how gyrases work at the molecular level can potentially improve clinical treatments. Read more ›

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ScienceDaily
ScienceDaily 2 place · 04/11/2024 16:58 EDT

New study finds potential targets at chromosome ends for degenerative disease prevention

A new study finds that telomere lengths follow a different pattern than has thus far been understood. Instead of telomere lengths falling under one general range of shortest to longest across all chromosomes, this study finds that different chromosomes have separate end-specific telomere-length distributions. Read more ›

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ScienceDaily
ScienceDaily 1 place · 04/11/2024 16:58 EDT

New approach for combating 'resting' bacteria

Most disease-causing bacteria are known for their speed: In mere minutes, they can double their population, quickly making a person sick. But just as dangerous as this rapid growth can be a bacterium's resting state, which helps the pathogen evade antibiotics and contributes to severe chronic infections in the lungs and blood, within wounds, and on the surfaces of medical devices. Now, scientists have discovered how long chains of molecules... Read more ›

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