How does the Earth generate its magnetic field? While the basic mechanisms seem to be understood, many details remain unresolved. A team of researchers has introduced a simulation method that promises new insights into the Earth's core. The method simulates not only the behavior of atoms, but also the magnetic properties of materials. The approach is significant for geophysics, but could also support the development of future technologies such as... Read more ›
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A lab has completed a six-year study to examine the virulence of 38 clinical isolates from various strains of Cryptococcus. Read more ›
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Researchers have developed a groundbreaking way to engineer yeast (Saccharomyces cerevisiae) to create microbial communities that can perform complex tasks and self-regulate their composition in response to external signals. Read more ›
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New research shows that many wildlife species in the U.S., like the endangered giant kangaroo rat, will face much more frequent and severe droughts in the future. By 2050-2080, year-long droughts could happen almost five times as often, and three-year droughts almost seven times as often compared to past decades. These changes will require animals to adapt significantly. Scientists have identified areas with high biodiversity and high risk that can... Read more ›
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Prostate cancer, especially in advanced stages such as castration-resistant prostate cancer, is challenging to treat. Traditional therapies targeting androgen receptor (AR) signaling have limited efficacy. In a recent study, researchers investigated the potential of azolato-bridged dinuclear platinum(II) complexes, particularly 5-H-Y, as promising alternatives. Their findings highlight the complex's ability to inhibit AR signaling and induce cell death in prostate cancer cells, providing a new avenue for pr Read more ›
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On February 2, 1887, residents of Punxsutawney Pennsylvania consulted a large rodent regarding the arrival of spring, marking the first official celebration of Groundhog Day. Our ability to predict the timing of seasons hasn't improved much since then, but a new study is set to make seasonal forecasting a lot more reliable. Read more ›
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The lateral habenula is a brain region associated with behavioral changes and autonomic responses during psychological stress. Researchers at the University of Tsukuba have identified the involvement of the dopaminergic system in the cardiovascular responses triggered by neuronal excitation in the lateral habenula. They further determined that the ventral tegmental area of the midbrain, which is the origin of dopamine neurons, plays a mediating role in this response. Read more ›
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A novel drug holds promise for treating Duchenne muscular dystrophy (DMD), a rare genetic disorder that causes severe muscle degeneration. Researchers have discovered that an experimental compound called K884 can boost the natural repair abilities of muscle stem cells. Current treatments can slow muscle damage, but don't address the root problem. Read more ›
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To fight the virus that causes influenza, one of the avenues being explored by scientists is the development of drugs capable of destabilizing its genome, made up of RNA molecules. But the challenge is daunting: each RNA molecule is tightly bound to an assembly of proteins which creates a double helix, forming a protective coat that is difficult to manipulate. Read more ›
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In the U.S., atrial fibrillation (AF), a heart condition that causes an irregular heartbeat in the upper chambers of the heart, affects up to one in three people in their lifetime. Significant complications associated with this condition include ischemic stroke, heart failure, myocardial infarction, chronic kidney disease, dementia and mortality. In a new review article scientists summarize the current evidence regarding the epidemiology, pathophysiology, diagnosis and management of AF. Read more ›
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Anthropologists argue physical artifacts of human exploration on Mars deserve cataloging, preservation and care in order to chronicle humanity's first attempts at interplanetary exploration. Read more ›
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After dozens of clinical trials, there are still no effective vaccines against Staphylococcus aureus. In two new studies, scientists report that the pathogen turns on the protein interleukin 10, shutting down the protective vaccine response. But blocking the protein restores vaccine efficacy in an animal model. Read more ›
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Researchers have gained new insights into the molecular changes leading to Rett syndrome, a severe neurological disorder caused by mutations in the MeCP2 gene encoding methyl-CpG binding protein 2 (MeCP2). The team reports that loss of MeCP2 in adulthood causes immediate progressive dysregulation of hundreds of genes -- some are activated while others are suppressed -- and these changes occur well before any measurable deficiencies in neurological function. Read more ›
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Researchers have discovered proteins with emulsifying action that can be readily released from yeast cell walls. One of them exhibited emulsifying activity comparable to that of casein, a milk-derived emulsifier. Read more ›
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Analysis of the remains of at least 37 individuals from Early Bronze Age England finds they were killed, butchered, and probably consumed before being thrown down a 15m-deep shaft. It is the largest-scale example of interpersonal violence from British prehistory. The treatment of the remains was likely a means to dehumanize or 'other' the victims. This massacre was probably revenge for a perceived offense, implying a cycle of violence and... Read more ›
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It's that time of the year when most of us get the chance to sit back and enjoy some well-deserved down time. But whether you reach for the TV controller, or a favorite book, your choice could have implications for your long-term brain health, say researchers. Read more ›
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A newly developed tool that harnesses computer vision and artificial intelligence (AI) may help clinicians from around the globe rapidly evaluate placentas at birth, potentially improving neonatal and maternal care. Early identification of placental infection could help mothers and babies receive antibiotics. The tool would be helpful for doctors in low-resource areas with no pathology labs or specialists to quickly spot issues. And in well-resourced hospitals, it could help doctors... Read more ›
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Immune checkpoint blockades, or ICBs, have revolutionized treatment for various advanced cancers. However, their effectiveness has plateaued due to therapeutic resistance that renders tumor-infiltrating lymphocytes, or TILs, ineffective. Thus, finding ways to disarm that resistance and rejuvenate anti-cancer TILs so they can kill tumor cells is an important goal for cancer clinicians. Read more ›
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A new study offers new evidence that dietary changes may help reduce cancer cell growth in patients undergoing active surveillance, a treatment approach that involves regular monitoring of the cancer without immediate intervention. Men on active surveillance who followed a low omega-6, high omega-3 diet with fish oil supplements had significantly lower levels of cancer cell proliferation after one year. Read more ›
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An analysis of national data found that short-term mortality was not impacted for patients with advanced cancers during the shortage of the generic platinum chemotherapy drugs cisplatin and carboplatin that began in early 2023. Read more ›
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25.06.2026 12:12
Last update: 12:06 EDT.
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