Spinal muscular atrophy (SMA) is a severe neurological disease for which there is presently no cure, although current therapies can alleviate symptoms. In the search for better treatment options, scientists are now drawing attention to previously unnoticed abnormalities in embryonic development. They base their argument on studies of so-called organoids: Laboratory-grown tissue cultures that can reconstruct disease processes. Read more ›
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Engineering researchers have demonstrated a state-of-the-art hardware device that could reduce energy consumption for artificial intelligent (AI) computing applications by a factor of at least 1,000. Read more ›
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The brain contains many cell types, from the prominent neurons to the lesser-known microglia. The latter are integral to the brain's immune system and play a crucial role as the brain's cleanup crew. A recent study highlights that microglia establish connections with neurons through tunneling nanotubes. The researchers observed that microglia utilize these tubes to facilitate the clearance of toxic proteins from neurons and to promote neuronal health. Read more ›
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When doctors sit at hospitalized patients' bedsides, it can have a more positive impact than if they stand, a review of data suggests -- but a new study seeks to find out for sure. Read more ›
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Lampreys are one of only two living jawless vertebrates Jaws are formed by a key stem cell population called the neural crest New research reveals the gene regulatory changes that may explain morphological differences between jawed and jawless vertebrates. Read more ›
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Researchers explain a new mechanism for ice formation. Ice can form near the free surface of a water droplet via small precursors with a structure resembling ice 0. These are readily formed by negative pressure effects due to surface tension, creating ring-like structures with the same characteristics as ice 0, which act as seeds for nucleation, providing a mechanism for the bulk formation of ice. Read more ›
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An experimental drug originally developed to treat cancer may help clear HIV from infected cells in the brain, according to a new study. By targeting infected cells in the brain, drug may clear virus from hidden areas that have been a major challenge in HIV treatment. Read more ›
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What puts the electronic pep in peptides? A folded structure, according to a new study. Researchers combined single-molecule experiments, molecular dynamics simulations and quantum mechanics to validate the findings. Read more ›
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The key to developing quantum electronics may have a few kinks. According to researchers, that's not a bad thing when it comes to the precise control needed to fabricate and operate such devices, including advanced sensors and lasers. The researchers fabricated a switch to turn on and off the presence of kink states, which are electrical conduction pathways at the edge of semiconducting materials. Read more ›
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Chemists have synthesized materials that can improve solar elements for indoor use. Such photovoltaic cells, which can also be integrated into various electronic devices, generate electricity even in low-light conditions. Read more ›
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An international team of researchers has found that nitrogen emissions from fertilizers and fossil fuels have a net cooling effect on the climate. But they warn increasing atmospheric nitrogen has further damaging effects on the environment, calling for an urgent reduction in greenhouse gas emissions to halt global warming. Read more ›
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Danish Tycho Brahe was most famous for his contributions to astronomy. However, he also had a well-equipped alchemical laboratory where he produced secret medicines for Europe's elite. Read more ›
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A new study brings researchers closer to better understanding the pathology of the fatty liver disease MASH, which stands for metabolic dysfunction-associated steatohepatitis. MASH is a consequence of poor diet and obesity and results in severe damage to the liver. In MASH, the liver becomes filled with active and rapidly multiplying T cells, which are a type of immune cell. In today's study researchers examine what these T cells look... Read more ›
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Researchers have found New Zealand's endangered flightless birds are seeking refuge in the locations where six species of moa last lived before going extinct. Read more ›
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Non-reciprocal interactions allow the design of more efficient molecular systems. Scientists now propose a mechanism on how energy barriers in complex systems can be overcome. These findings can help to engineer molecular machines and to understand the self-organization of active matter. Read more ›
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Findings from a small, proof-of-concept clinical trial have suggested that fecal microbiota transplants (FMTs) can boost the effectiveness of immunotherapy in a range of gastrointestinal cancers. In the study, six of 13 patients who had previously shown resistance to immune checkpoint inhibitors benefited from receiving FMTs from donors who had previously responded to treatment. The investigators also identified specific strains of bacteria associated with better or worse responses to FMT... Read more ›
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Mammals that have evolved more developed brains tend to have a smaller size difference between males and females of that species, according to new research. Read more ›
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Aerosol scientists quantify the extent of light absorption by black carbon in fire clouds to better model climate impacts of extreme wildfire events. Read more ›
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A gentle rumble ran under a researcher's feet as a rocket carrying her research -- live, human muscle cells grown on scaffolds fixed on tiny chips -- lifted off, climbed, and disappeared into the sky to the International Space Station National Laboratory. These chips would help her better understand muscle impairment, often seen in astronauts and older adults, and test drugs to counter the condition. Read more ›
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A new mathematical method, validated with experimental animal data, provides a fast, reliable and minimally invasive way of determining how to treat critical blood pressure changes during surgery or intensive care. Read more ›
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29.11.2024 21:49
Last update: 21:25 EDT.
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